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The company also develops OBP-601(Censavudine), which is in phase II clinical trial to treat progressive supranuclear palsy, amyotrophic lateral sclerosis, and aicardi-goutieres syndrome; OBP-702, which is in preclinical trial to treat pancreatic cancer; OBP-201, which is in preclinical trial to treat viral infections; OBP-702 for the treatment of ophthalmology which is in preclinical trial. In addition, it develops TelomeScan (OBP-401 and OBP-1101), which is in pilot study trial to treat cancer testing. The company was incorporated in 2004 and is headquartered in Minato, Japan.", "setup_signature": "Balanced read", "composite_score": "63", "kpis": [{"label": "Latest Close", "value": "2,848 JPY", "hint": "2026-08-07"}, {"label": "1W Return", "value": "6.9%", "tone": "positive", "hint": "latest completed week"}, {"label": "4W Return", "value": "10.6%", "tone": "positive", "hint": "short-term follow-through"}, {"label": "12W Return", "value": "6.3%", "tone": "positive", "hint": "quarterly tape"}, {"label": "Trend Breadth", "value": "100.0%", "hint": "52 of 52 weeks active"}, {"label": "Volume Ratio", "value": "1.1x", "hint": "vs 13-week average"}], "classification": {"exchange": "JPX", "country": "JP", "sector": "Healthcare", "industry": "Biotechnology", "currency": "JPY", "market_cap": "81.0B"}, "price": {"trend_line": "2,522 JPY", "fair_value": "1,011 JPY", "vs_trend": "12.9%", "vs_fair_value": "181.6%", "high_52": "3,695 JPY", "low_52": "601.0 JPY", "drawdown": "-22.9%", 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"3 Jul", "return": -1.9392608854738382, "return_label": "-1.9%", "return_tone": "negative", "volume_height": 5.808139666022571, "volume": "772.5K"}, {"week": "10 Jul", "return": -3.9179104477611943, "return_label": "-3.9%", "return_tone": "negative", "volume_height": 22.166417298857922, "volume": "2.9M"}, {"week": "17 Jul", "return": -8.699029126213592, "return_label": "-8.7%", "return_tone": "negative", "volume_height": 20.039397607572763, "volume": "2.7M"}, {"week": "24 Jul", "return": 5.019140791152701, "return_label": "5.0%", "return_tone": "positive", "volume_height": 11.732066193995625, "volume": "1.6M"}, {"week": "31 Jul", "return": 7.938436614013771, "return_label": "7.9%", "return_tone": "positive", "volume_height": 18.368006736690152, "volume": "2.4M"}, {"week": "7 Aug", "return": 6.866791744840525, "return_label": "6.9%", "return_tone": "positive", "volume_height": 34.84207123147598, "volume": "4.6M"}], "insights": [{"label": "Participation", "value": "1.1x", "detail": "Latest volume versus the 13-week average.", "tone": "neutral"}, {"label": "Baseline", "value": "4.1M", "detail": "13-week average volume.", "tone": "neutral"}, {"label": "One-year base", "value": "7.8M", "detail": "52-week average volume.", "tone": "neutral"}]}, "risk": {"volatility_13": "5.8%", "volatility_52": "12.5%", "downside_weeks": 21, "upside_weeks": 30, "downside_breadth": "40.4%", "average_gain": "12.3%", "average_loss": "-8.2%", "distribution_scale": "31%", "return_callouts": [{"label": "Weeks higher", "value": "14 of 26", "detail": "12 weeks finished lower.", "tone": "positive"}, {"label": "Best week", "value": "+30.3%", "detail": "Week of 13 Feb.", "tone": "positive"}, {"label": "Worst week", "value": "-16.9%", "detail": "Week of 20 Mar.", "tone": "negative"}, {"label": "Latest week", "value": "+6.9%", "detail": "Week of 7 Aug.", "tone": "positive"}], "buckets": [{"label": "Strong gains", "count": 14, "share": 53.84615384615385, "share_label": "53.8%", "tone": "positive"}, {"label": "Modest gains", "count": 0, "share": 0.0, "share_label": "0.0%", "tone": "positive"}, {"label": "Flat weeks", "count": 0, "share": 0.0, "share_label": "0.0%", "tone": "neutral"}, {"label": "Modest losses", "count": 4, "share": 15.384615384615385, "share_label": "15.4%", "tone": "negative"}, {"label": "Sharp losses", "count": 8, "share": 30.76923076923077, "share_label": "30.8%", "tone": "negative"}], "insights": [{"label": "Recent vol", "value": "5.8%", "detail": "13-week weekly-return volatility.", "tone": "neutral"}, {"label": "Base vol", "value": "12.5%", "detail": "52-week weekly-return volatility.", "tone": "neutral"}, {"label": "Up/down split", "value": "30/21", "detail": "Count of positive and negative weeks in the 52-week window.", "tone": "positive"}, {"label": "Average skew", "value": "12.3% / -8.2%", "detail": "Average positive week versus average negative week.", "tone": "neutral"}]}, "signals": [{"label": "Trend backdrop", "value": "Active", "tone": "positive"}, {"label": "Activity pressure", "value": "No fresh buy", "tone": "neutral"}, {"label": "Price vs Trend", "value": "12.9%", "tone": "positive"}, {"label": "Volume", "value": "1.1x", "tone": "neutral"}], "opportunities": ["The trend backdrop is active with a 52-week active streak.", "Price is above the Trend Line, keeping the weekly tape constructive.", "Price is above Fair Value, showing premium demand versus the model.", "Activity pressure is constructive, supporting the smart-money activity read.", "Latest weekly return ranks in the strongest part of its sector group."], "risks": ["Activity pressure is negative, which weakens the current setup.", "The share remains more than 20% below its 52-week high."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade.", "A volume ratio above 1.5x would show stronger participation in the next move."], "recent_rows": [{"week": "2026-08-07", "close": "2,848 JPY", "return": null, "return_tone": null, "trend_line": "2,522 JPY", "fair_value": "1,011 JPY", "activity_pressure": "-0.85", "relative_leadership": "36.93", "volume": "4.6M", "trend_backdrop": null}, {"week": "2026-07-31", "close": "2,665 JPY", "return": null, "return_tone": null, "trend_line": "2,478 JPY", "fair_value": "997.0 JPY", "activity_pressure": "-1.00", "relative_leadership": "32.95", "volume": "2.4M", "trend_backdrop": null}, {"week": "2026-07-24", "close": "2,469 JPY", "return": null, "return_tone": null, "trend_line": "2,435 JPY", "fair_value": "983.3 JPY", "activity_pressure": "-0.94", "relative_leadership": "24.79", "volume": "1.6M", "trend_backdrop": null}, {"week": "2026-07-17", "close": "2,351 JPY", "return": null, "return_tone": null, "trend_line": "2,389 JPY", "fair_value": "970.9 JPY", "activity_pressure": "-0.75", "relative_leadership": "21.52", "volume": "2.7M", "trend_backdrop": null}, {"week": "2026-07-10", "close": "2,575 JPY", "return": null, "return_tone": null, "trend_line": "2,340 JPY", "fair_value": "959.2 JPY", "activity_pressure": "-0.70", "relative_leadership": "26.24", "volume": "2.9M", "trend_backdrop": null}, {"week": "2026-07-03", "close": "2,680 JPY", "return": null, "return_tone": null, "trend_line": "2,289 JPY", "fair_value": "946.2 JPY", "activity_pressure": "-0.79", "relative_leadership": "30.96", "volume": "772.5K", "trend_backdrop": null}, {"week": "2026-06-26", "close": "2,733 JPY", "return": null, "return_tone": null, "trend_line": "2,231 JPY", "fair_value": "932.9 JPY", "activity_pressure": "-0.85", "relative_leadership": "36.37", "volume": "627.1K", "trend_backdrop": null}, {"week": "2026-06-19", "close": "2,591 JPY", "return": null, "return_tone": null, "trend_line": "2,179 JPY", "fair_value": "919.7 JPY", "activity_pressure": "-0.79", "relative_leadership": "27.88", "volume": "839.2K", "trend_backdrop": null}, {"week": "2026-06-12", "close": "2,467 JPY", "return": null, "return_tone": null, "trend_line": "2,125 JPY", "fair_value": "907.6 JPY", "activity_pressure": "-0.55", "relative_leadership": "33.24", "volume": "1.5M", "trend_backdrop": null}, {"week": "2026-06-05", "close": "2,614 JPY", "return": null, "return_tone": null, "trend_line": "2,078 JPY", "fair_value": "895.9 JPY", "activity_pressure": "-0.34", "relative_leadership": "42.04", "volume": "1.4M", "trend_backdrop": null}, {"week": "2026-05-29", "close": "2,765 JPY", "return": null, "return_tone": null, "trend_line": "2,019 JPY", "fair_value": "883.4 JPY", "activity_pressure": "-0.19", "relative_leadership": "53.14", "volume": "11.5M", "trend_backdrop": null}, {"week": "2026-05-22", "close": "2,797 JPY", "return": null, "return_tone": null, "trend_line": "1,952 JPY", "fair_value": "869.5 JPY", "activity_pressure": "-0.25", "relative_leadership": "65.17", "volume": "13.3M", "trend_backdrop": null}, {"week": "2026-05-15", "close": "2,680 JPY", "return": null, "return_tone": null, "trend_line": "1,882 JPY", "fair_value": "855.5 JPY", "activity_pressure": "-0.22", "relative_leadership": "66.87", "volume": "8.5M", "trend_backdrop": null}, {"week": "2026-05-08", "close": "2,918 JPY", "return": null, "return_tone": null, "trend_line": "1,816 JPY", "fair_value": "842.2 JPY", "activity_pressure": "-0.15", "relative_leadership": "81.87", "volume": "1.2M", "trend_backdrop": null}], "intelligence": {"rating": "Neutral", "rating_tone": "neutral", "overall_score": "58", "primary_driver": {"label": "Weekly tape", "score": 63.547734366920935, "score_label": "64", "tone": "neutral", "summary": "Trend, activity pressure, participation, and risk combine to a 64/100 tape read.", "detail": "", "metric": "64/100", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 1.6}, "primary_conflict": {"label": "Weekly tape", "score": 63.547734366920935, "score_label": "64", "tone": "neutral", "summary": "Trend, activity pressure, participation, and risk combine to a 64/100 tape read.", "detail": "", "metric": "64/100", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 1.6}, "options_tone": "neutral", "options": null, "evidence": [{"label": "Weekly tape", "score": 63.547734366920935, "score_label": "64", "tone": "neutral", "summary": "Trend, activity pressure, participation, and risk combine to a 64/100 tape read.", "detail": "", "metric": "64/100", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 1.6}, {"label": "Indicator analysis", "score": 63.14583333333333, "score_label": "63", "tone": "neutral", "summary": "Latest 12-week confirmation: trend 12/12, activity pressure 0/12, relative leadership 12/12.", "detail": "Activity pressure 0.59; No reversal markers", "metric": "63/100", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 1.45}, {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, {"label": "Sentiment", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "Weighted news tone is neutral across 2 relevant articles.", "detail": "Japan backs Oncolys virus therapy for esophageal cancer", "metric": "50/100", "url": "/sentiment/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 0.95}, {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}], "positives": [], "negatives": [], "conclusion": ["The strongest supporting evidence is weekly tape: Trend, activity pressure, participation, and risk combine to a 64/100 tape read.", "The combined read is balanced, making the next change in trend, sentiment, or options pressure especially important."], "weekly_changes": [{"label": "Price follow-through", "value": "6.9%", "detail": "Latest completed week; four-week move 10.6%.", "tone": "positive", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}, {"label": "Indicator stack", "value": "100/33", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "negative", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}, {"label": "News sentiment", "value": "50/100", "detail": "2 relevant articles in the latest sentiment read.", "tone": "neutral", "url": "/sentiment/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}]}, "investor_view": {"stance": "Constructive, but selective", "stance_tone": "positive", "setup_score": "63", "bottom_line": "The weekly trend is active. Price is 12.9% above the Trend Line and sits at 72.6% of its 52-week range. The latest completed week returned 6.9%, after a 10.6% four-week move. The latest news-sentiment score is 50/100.", "price_summary": "The weekly trend is active. Price is 12.9% above the Trend Line and sits at 72.6% of its 52-week range. The latest completed week returned 6.9%, after a 10.6% four-week move.", "volume_summary": "Latest weekly volume is 1.1x the 13-week average. Participation is around or above normal and provides reasonable confirmation.", "momentum_summary": "Performance is 10.6% over four weeks, 6.3% over 12 weeks, and 373.1% over one year. The current trend has remained active for 52 consecutive weeks.", "fundamentals": {"available": false, "summary": "A published fundamentals and factor snapshot is not available for this company.", "rank_scores": [], "groups": []}, "weekly_change": [{"label": "Price follow-through", "value": "6.9%", "detail": "Latest completed week; four-week move 10.6%.", "tone": "positive", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}, {"label": "Indicator stack", "value": "100/33", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "negative", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}, {"label": "News sentiment", "value": "50/100", "detail": "2 relevant articles in the latest sentiment read.", "tone": "neutral", "url": "/sentiment/40cf0b38-b790-4af4-96d1-1b07d4b3929d/"}], "strengths": ["The trend backdrop is active with a 52-week active streak.", "Price is above the Trend Line, keeping the weekly tape constructive.", "Price is above Fair Value, showing premium demand versus the model.", "Activity pressure is constructive, supporting the smart-money activity read."], "risks": ["Activity pressure is negative, which weakens the current setup.", "The share remains more than 20% below its 52-week high."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade.", "A volume ratio above 1.5x would show stronger participation in the next move."], "evidence": {"weekly_tape": {"label": "Weekly tape", "score": 63.547734366920935, "score_label": "64", "tone": "neutral", "summary": "Trend, activity pressure, participation, and risk combine to a 64/100 tape read.", "detail": "", "metric": "64/100", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 1.6}, "indicator_analysis": {"label": "Indicator analysis", "score": 63.14583333333333, "score_label": "63", "tone": "neutral", "summary": "Latest 12-week confirmation: trend 12/12, activity pressure 0/12, relative leadership 12/12.", "detail": "Activity pressure 0.59; No reversal markers", "metric": "63/100", "url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 1.45}, "factors": {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, "patient_capital": {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, "sentiment": {"label": "Sentiment", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "Weighted news tone is neutral across 2 relevant articles.", "detail": "Japan backs Oncolys virus therapy for esophageal cancer", "metric": "50/100", "url": "/sentiment/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "available": true, "weight": 0.95}, "insiders": {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, "earnings": {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}}, "section_nav": [{"id": "overview", "label": "Overview"}, {"id": "price-action", "label": "Price"}, {"id": "volume-demand", "label": "Volume"}, {"id": "momentum", "label": "Momentum"}, {"id": "fundamentals", "label": "Fundamentals"}, {"id": "ownership-flow", "label": "Ownership & Flow"}, {"id": "catalysts-risk", "label": "Catalysts & Risk"}, {"id": "peer-context", "label": "Peer Context"}, {"id": "weekly-data", "label": "Weekly Data"}]}, "chart_url": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/", "api_path": "/terminal/40cf0b38-b790-4af4-96d1-1b07d4b3929d/report/api/"}