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It is also developing Roxadustat, a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase activity, which has completed Phase III clinical development for the treatment of anemia in chronic kidney disease in the United States, Europe, Japan, and other countries, as well as in Phase III clinical development for anemia related with myelodysplastic syndromes. The company has collaboration agreements with Astellas Pharma Inc. and AstraZeneca AB. The company was formerly known as FibroGen, Inc. and change its name to Kyntra Bio, Inc. in January 2026. Kyntra Bio, Inc. was incorporated in 1993 and is headquartered in San Francisco, California.", "setup_signature": "Risk-first tape", "composite_score": "31", "kpis": [{"label": "Latest Close", "value": "127.9 MXN", "hint": "2026-07-24"}, {"label": "1W Return", "value": "0.0%", "tone": "neutral", "hint": "latest completed week"}, {"label": "4W Return", "value": "7.9%", "tone": "positive", "hint": "short-term follow-through"}, {"label": "12W Return", "value": "6.6%", "tone": "positive", "hint": "quarterly tape"}, {"label": "Trend Breadth", "value": "19.2%", "hint": "10 of 52 weeks active"}, {"label": "Volume Ratio", "value": "-", "hint": "vs 13-week average"}], "classification": {"exchange": "MEX", "country": "MX", "sector": "Healthcare", "industry": "Biotechnology", "currency": "MXN", "market_cap": "479.7M"}, "price": {"trend_line": "130.7 MXN", "fair_value": "341.7 MXN", "vs_trend": "-2.2%", "vs_fair_value": "-62.6%", "high_52": "225.0 MXN", "low_52": "118.2 MXN", "drawdown": "-43.2%", 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"return_label": "7.9%", "return_tone": "positive", "volume_height": 4, "volume": "5"}, {"week": "17 Jul", "return": 0.0, "return_label": "0.0%", "return_tone": "neutral", "volume_height": 4, "volume": "0"}, {"week": "24 Jul", "return": 0.0, "return_label": "0.0%", "return_tone": "neutral", "volume_height": 4, "volume": "0"}], "insights": [{"label": "Participation", "value": "-", "detail": "Latest volume versus the 13-week average.", "tone": "neutral"}, {"label": "Baseline", "value": "15", "detail": "13-week average volume.", "tone": "neutral"}, {"label": "One-year base", "value": "177", "detail": "52-week average volume.", "tone": "neutral"}]}, "risk": {"volatility_13": "2.2%", "volatility_52": "6.7%", "downside_weeks": 13, "upside_weeks": 10, "downside_breadth": "25.0%", "average_gain": "8.7%", "average_loss": "-6.7%", "distribution_scale": "15%", "return_callouts": [{"label": "Weeks higher", "value": "2 of 26", "detail": "4 weeks finished lower.", "tone": "negative"}, {"label": "Best week", "value": "+7.9%", "detail": "Week of 10 Jul.", "tone": "positive"}, {"label": "Worst week", "value": "-14.5%", "detail": "Week of 20 Mar.", "tone": "negative"}, {"label": "Latest week", "value": "+0.0%", "detail": "Week of 24 Jul.", "tone": "neutral"}], "buckets": [{"label": "Strong gains", "count": 1, "share": 3.8461538461538463, "share_label": "3.8%", "tone": "positive"}, {"label": "Modest gains", "count": 1, "share": 3.8461538461538463, "share_label": "3.8%", "tone": "positive"}, {"label": "Flat weeks", "count": 20, "share": 76.92307692307693, "share_label": "76.9%", "tone": "neutral"}, {"label": "Modest losses", "count": 2, "share": 7.6923076923076925, "share_label": "7.7%", "tone": "negative"}, {"label": "Sharp losses", "count": 2, "share": 7.6923076923076925, "share_label": "7.7%", "tone": "negative"}], "insights": [{"label": "Recent vol", "value": "2.2%", "detail": "13-week weekly-return volatility.", "tone": "neutral"}, {"label": "Base vol", "value": "6.7%", "detail": "52-week weekly-return volatility.", "tone": "neutral"}, {"label": "Up/down split", "value": "10/13", "detail": "Count of positive and negative weeks in the 52-week window.", "tone": "negative"}, {"label": "Average skew", "value": "8.7% / -6.7%", "detail": "Average positive week versus average negative week.", "tone": "neutral"}]}, "signals": [{"label": "Trend backdrop", "value": "Inactive", "tone": "negative"}, {"label": "Activity pressure", "value": "No fresh buy", "tone": "neutral"}, {"label": "Price vs Trend", "value": "-2.2%", "tone": "negative"}, {"label": "Volume", "value": "-", "tone": "neutral"}], "opportunities": ["Activity pressure is positive on the latest completed week."], "risks": ["The trend backdrop is inactive, so price action has not confirmed a constructive regime.", "Price is below the Trend Line, which keeps downside pressure in focus.", "Price is below Fair Value, so the market is still discounting the latest tape.", "Next-week expectancy is negative at 25.00% based on similar historical setup states.", "Activity pressure is weak, so confirmation is not yet broad enough."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade."], "recent_rows": [{"week": "2026-07-24", "close": "127.9 MXN", "return": null, "return_tone": null, "trend_line": "130.7 MXN", "fair_value": "341.7 MXN", "activity_pressure": "0.91", "relative_leadership": "-18.65", "volume": "0", "trend_backdrop": null}, {"week": "2026-07-17", "close": "127.9 MXN", "return": null, "return_tone": null, "trend_line": "131.6 MXN", "fair_value": "395.6 MXN", "activity_pressure": "0.75", "relative_leadership": "-19.36", "volume": "0", "trend_backdrop": null}, {"week": "2026-07-10", "close": "127.9 MXN", "return": null, "return_tone": null, "trend_line": "132.5 MXN", "fair_value": "449.5 MXN", "activity_pressure": "0.47", "relative_leadership": "-19.62", "volume": "5", "trend_backdrop": null}, {"week": "2026-07-03", "close": "118.5 MXN", "return": null, "return_tone": null, "trend_line": "133.4 MXN", "fair_value": "503.3 MXN", "activity_pressure": "0.15", "relative_leadership": "-26.22", "volume": "0", "trend_backdrop": null}, {"week": "2026-06-26", "close": "118.5 MXN", "return": null, "return_tone": null, "trend_line": "134.5 MXN", "fair_value": "557.2 MXN", "activity_pressure": "-0.05", "relative_leadership": "-26.48", "volume": "0", "trend_backdrop": null}, {"week": "2026-06-19", "close": "118.5 MXN", "return": null, "return_tone": null, "trend_line": "136.1 MXN", "fair_value": "611.2 MXN", "activity_pressure": "-0.18", "relative_leadership": "-27.08", "volume": "0", "trend_backdrop": null}, {"week": "2026-06-12", "close": "118.2 MXN", "return": null, "return_tone": null, "trend_line": "137.7 MXN", "fair_value": "665.1 MXN", "activity_pressure": "-0.31", "relative_leadership": "-27.60", "volume": "0", "trend_backdrop": null}, {"week": "2026-06-05", "close": "118.2 MXN", "return": null, "return_tone": null, "trend_line": "139.3 MXN", "fair_value": "719.0 MXN", "activity_pressure": "-0.46", "relative_leadership": "-26.01", "volume": "0", "trend_backdrop": null}, {"week": "2026-05-29", "close": "118.5 MXN", "return": null, "return_tone": null, "trend_line": "142.3 MXN", "fair_value": "772.9 MXN", "activity_pressure": "-0.63", "relative_leadership": "-28.91", "volume": "185", "trend_backdrop": null}, {"week": "2026-05-22", "close": "120.0 MXN", "return": null, "return_tone": null, "trend_line": "145.0 MXN", "fair_value": "826.8 MXN", "activity_pressure": "-0.92", "relative_leadership": "-28.30", "volume": "0", "trend_backdrop": null}, {"week": "2026-05-15", "close": "120.0 MXN", "return": null, "return_tone": null, "trend_line": "147.6 MXN", "fair_value": "880.8 MXN", "activity_pressure": "-1.06", "relative_leadership": "-28.36", "volume": "0", "trend_backdrop": null}, {"week": "2026-05-08", "close": "120.0 MXN", "return": null, "return_tone": null, "trend_line": "150.3 MXN", "fair_value": "934.7 MXN", "activity_pressure": "-1.15", "relative_leadership": "-30.71", "volume": "0", "trend_backdrop": null}, {"week": "2026-05-01", "close": "120.0 MXN", "return": null, "return_tone": null, "trend_line": "153.1 MXN", "fair_value": "988.6 MXN", "activity_pressure": "-1.14", "relative_leadership": "-29.29", "volume": "0", "trend_backdrop": null}, {"week": "2026-04-24", "close": "120.0 MXN", "return": null, "return_tone": null, "trend_line": "156.4 MXN", "fair_value": "1,042 MXN", "activity_pressure": "-1.09", "relative_leadership": "-31.34", "volume": "0", "trend_backdrop": null}], "intelligence": {"rating": "Caution", "rating_tone": "negative", "overall_score": "33", "primary_driver": {"label": "Sentiment", "score": 51.0, "score_label": "51", "tone": "neutral", "summary": "Weighted news tone is neutral across 15 relevant articles.", "detail": "Kyntra Bio, Inc. Revenue Breakdown \u2013 NASDAQ:KYNB", "metric": "51/100", "url": "/sentiment/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 0.95}, "primary_conflict": {"label": "Indicator analysis", "score": 16.777777777777775, "score_label": "17", "tone": "negative", "summary": "Latest 12-week confirmation: trend 0/12, activity pressure 4/12, relative leadership 0/12.", "detail": "Activity pressure 0.08; No reversal markers", "metric": "17/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.45}, "options_tone": "neutral", "options": null, "evidence": [{"label": "Weekly tape", "score": 26.558236929086537, "score_label": "27", "tone": "negative", "summary": "Trend, activity pressure, participation, and risk combine to a 27/100 tape read.", "detail": "", "metric": "27/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.6}, {"label": "Indicator analysis", "score": 16.777777777777775, "score_label": "17", "tone": "negative", "summary": "Latest 12-week confirmation: trend 0/12, activity pressure 4/12, relative leadership 0/12.", "detail": "Activity pressure 0.08; No reversal markers", "metric": "17/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.45}, {"label": "Next-Week Expectancy", "score": 37.5, "score_label": "38", "tone": "negative", "summary": "Next-week expectancy is negative with a 25.00% historical one-week setup read.", "detail": "Adds short-term historical context without overriding trend, activity, or relative leadership.", "metric": "Negative 25.00%", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.05}, {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, {"label": "Sentiment", "score": 51.0, "score_label": "51", "tone": "neutral", "summary": "Weighted news tone is neutral across 15 relevant articles.", "detail": "Kyntra Bio, Inc. Revenue Breakdown \u2013 NASDAQ:KYNB", "metric": "51/100", "url": "/sentiment/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 0.95}, {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}], "positives": [], "negatives": [{"label": "Indicator analysis", "score": 16.777777777777775, "score_label": "17", "tone": "negative", "summary": "Latest 12-week confirmation: trend 0/12, activity pressure 4/12, relative leadership 0/12.", "detail": "Activity pressure 0.08; No reversal markers", "metric": "17/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.45}, {"label": "Weekly tape", "score": 26.558236929086537, "score_label": "27", "tone": "negative", "summary": "Trend, activity pressure, participation, and risk combine to a 27/100 tape read.", "detail": "", "metric": "27/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.6}, {"label": "Next-Week Expectancy", "score": 37.5, "score_label": "38", "tone": "negative", "summary": "Next-week expectancy is negative with a 25.00% historical one-week setup read.", "detail": "Adds short-term historical context without overriding trend, activity, or relative leadership.", "metric": "Negative 25.00%", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.05}], "conclusion": ["The strongest supporting evidence is sentiment: Weighted news tone is neutral across 15 relevant articles.", "The main constraint is indicator analysis: Latest 12-week confirmation: trend 0/12, activity pressure 4/12, relative leadership 0/12.", "The combined read is defensive, so risk control and evidence of stabilization matter more than headline upside."], "weekly_changes": [{"label": "Price follow-through", "value": "0.0%", "detail": "Latest completed week; four-week move 7.9%.", "tone": "neutral", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "Indicator stack", "value": "11/100", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "negative", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}, {"label": "Next-Week Expectancy", "value": "Negative 25.00%", "detail": "Historical one-week expectancy contributes to the evidence score when direction is confirmed.", "tone": "negative", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "News sentiment", "value": "51/100", "detail": "15 relevant articles in the latest sentiment read.", "tone": "neutral", "url": "/sentiment/acf4e837-cb0e-4313-bee2-27be0e439350/"}]}, "investor_view": {"stance": "Mixed setup", "stance_tone": "neutral", "setup_score": "31", "bottom_line": "The weekly trend is not active. Price is -2.2% below the Trend Line and sits at 9.1% of its 52-week range. The latest completed week returned 0.0%, after a 7.9% four-week move. The latest news-sentiment score is 51/100.", "price_summary": "The weekly trend is not active. Price is -2.2% below the Trend Line and sits at 9.1% of its 52-week range. The latest completed week returned 0.0%, after a 7.9% four-week move.", "volume_summary": "Latest weekly volume is - the 13-week average. Participation data is incomplete.", "momentum_summary": "Performance is 7.9% over four weeks, 6.6% over 12 weeks, and -11.8% over one year. The current trend has remained active for 0 consecutive weeks.", "fundamentals": {"available": false, "summary": "A published fundamentals and factor snapshot is not available for this company.", "rank_scores": [], "groups": []}, "weekly_change": [{"label": "Price follow-through", "value": "0.0%", "detail": "Latest completed week; four-week move 7.9%.", "tone": "neutral", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "Indicator stack", "value": "11/100", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "negative", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}, {"label": "Next-Week Expectancy", "value": "Negative 25.00%", "detail": "Historical one-week expectancy contributes to the evidence score when direction is confirmed.", "tone": "negative", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/"}, {"label": "News sentiment", "value": "51/100", "detail": "15 relevant articles in the latest sentiment read.", "tone": "neutral", "url": "/sentiment/acf4e837-cb0e-4313-bee2-27be0e439350/"}], "strengths": ["Activity pressure is positive on the latest completed week."], "risks": ["The trend backdrop is inactive, so price action has not confirmed a constructive regime.", "Price is below the Trend Line, which keeps downside pressure in focus.", "Price is below Fair Value, so the market is still discounting the latest tape.", "Next-week expectancy is negative at 25.00% based on similar historical setup states."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade."], "evidence": {"weekly_tape": {"label": "Weekly tape", "score": 26.558236929086537, "score_label": "27", "tone": "negative", "summary": "Trend, activity pressure, participation, and risk combine to a 27/100 tape read.", "detail": "", "metric": "27/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.6}, "indicator_analysis": {"label": "Indicator analysis", "score": 16.777777777777775, "score_label": "17", "tone": "negative", "summary": "Latest 12-week confirmation: trend 0/12, activity pressure 4/12, relative leadership 0/12.", "detail": "Activity pressure 0.08; No reversal markers", "metric": "17/100", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.45}, "next-week_expectancy": {"label": "Next-Week Expectancy", "score": 37.5, "score_label": "38", "tone": "negative", "summary": "Next-week expectancy is negative with a 25.00% historical one-week setup read.", "detail": "Adds short-term historical context without overriding trend, activity, or relative leadership.", "metric": "Negative 25.00%", "url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 1.05}, "factors": {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, "patient_capital": {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, "sentiment": {"label": "Sentiment", "score": 51.0, "score_label": "51", "tone": "neutral", "summary": "Weighted news tone is neutral across 15 relevant articles.", "detail": "Kyntra Bio, Inc. Revenue Breakdown \u2013 NASDAQ:KYNB", "metric": "51/100", "url": "/sentiment/acf4e837-cb0e-4313-bee2-27be0e439350/", "available": true, "weight": 0.95}, "insiders": {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, "earnings": {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}}, "section_nav": [{"id": "overview", "label": "Overview"}, {"id": "price-action", "label": "Price"}, {"id": "volume-demand", "label": "Volume"}, {"id": "momentum", "label": "Momentum"}, {"id": "fundamentals", "label": "Fundamentals"}, {"id": "ownership-flow", "label": "Ownership & Flow"}, {"id": "catalysts-risk", "label": "Catalysts & Risk"}, {"id": "peer-context", "label": "Peer Context"}, {"id": "weekly-data", "label": "Weekly Data"}]}, "chart_url": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/", "api_path": "/terminal/acf4e837-cb0e-4313-bee2-27be0e439350/report/api/"}