{"ticker": {"uuid": "adbc8547-2152-4123-86b9-f5e77c6920f1", "symbol": "6446", "name": "PharmaEssentia Corporation", "exchange": "TAI", "asset_type": "equity"}, "latest_week": "2026-08-07", "summary": "6446 closed the latest completed week at 1,240 TWD. The 4-week return is -3.5% and the 12-week return is 66.7%. The trend backdrop is active, with activity pressure at 0.95.", "description": "PharmaEssentia Corporation, a biopharmaceutical company engages in medicine discovery, supplements in developing specialty pharmaceutical reagents, API, and new drug patterns developments in the Americas, Europe, Asia, and Taiwan. Its products include BESREMi, an interferon therapy indicated for polycythemia vera, essential thrombocythemia, PMF, and adult T-cell leukemias. The company also develops Ropeg + anti PD-1; PEG-IL-2 (P11838); PEG-Cytokines; PD-1-IL-2v; ADC; ADCS; NY-ESO-1 TCR-T; and Novel TCR-T for the treatment of solid tumor and immunology. 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"11.0M"}, {"week": "31 Jul", "return": -6.607929515418502, "return_label": "-6.6%", "return_tone": "negative", "volume_height": 50.07580004680698, "volume": "14.5M"}, {"week": "7 Aug", "return": 16.9811320754717, "return_label": "17.0%", "return_tone": "positive", "volume_height": 64.54669384637631, "volume": "18.6M"}], "insights": [{"label": "Participation", "value": "1.1x", "detail": "Latest volume versus the 13-week average.", "tone": "neutral"}, {"label": "Baseline", "value": "17.0M", "detail": "13-week average volume.", "tone": "neutral"}, {"label": "One-year base", "value": "13.2M", "detail": "52-week average volume.", "tone": "neutral"}]}, "risk": {"volatility_13": "9.2%", "volatility_52": "7.4%", "downside_weeks": 23, "upside_weeks": 28, "downside_breadth": "44.2%", "average_gain": "7.0%", "average_loss": "-3.1%", "distribution_scale": "21%", "return_callouts": [{"label": "Weeks higher", "value": "14 of 26", "detail": "11 weeks finished lower.", "tone": "positive"}, {"label": "Best week", "value": "+20.8%", "detail": "Week of 3 Jul.", "tone": "positive"}, {"label": "Worst week", "value": "-7.0%", "detail": "Week of 17 Jul.", "tone": "negative"}, {"label": "Latest week", "value": "+17.0%", "detail": "Week of 7 Aug.", "tone": "positive"}], "buckets": [{"label": "Strong gains", "count": 8, "share": 30.76923076923077, "share_label": "30.8%", "tone": "positive"}, {"label": "Modest gains", "count": 6, "share": 23.076923076923077, "share_label": "23.1%", "tone": "positive"}, {"label": "Flat weeks", "count": 1, "share": 3.8461538461538463, "share_label": "3.8%", "tone": "neutral"}, {"label": "Modest losses", "count": 5, "share": 19.230769230769234, "share_label": "19.2%", "tone": "negative"}, {"label": "Sharp losses", "count": 6, "share": 23.076923076923077, "share_label": "23.1%", "tone": "negative"}], "insights": [{"label": "Recent vol", "value": "9.2%", "detail": "13-week weekly-return volatility.", "tone": "neutral"}, {"label": "Base vol", "value": "7.4%", "detail": "52-week weekly-return volatility.", "tone": "neutral"}, {"label": "Up/down split", "value": "28/23", "detail": "Count of positive and negative weeks in the 52-week window.", "tone": "positive"}, {"label": "Average skew", "value": "7.0% / -3.1%", "detail": "Average positive week versus average negative week.", "tone": "neutral"}]}, "signals": [{"label": "Trend backdrop", "value": "Active", "tone": "positive"}, {"label": "Activity pressure", "value": "No fresh buy", "tone": "neutral"}, {"label": "Price vs Trend", "value": "59.9%", "tone": "positive"}, {"label": "Volume", "value": "1.1x", "tone": "neutral"}], "opportunities": ["The trend backdrop is active with a 44-week active streak.", "Price is above the Trend Line, keeping the weekly tape constructive.", "Price is above Fair Value, showing premium demand versus the model.", "Activity pressure is positive on the latest completed week.", "Activity pressure is constructive, supporting the smart-money activity read."], "risks": ["No major top-level risk cluster is currently dominant."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade.", "A volume ratio above 1.5x would show stronger participation in the next move."], "recent_rows": [{"week": "2026-08-07", "close": "1,240 TWD", "return": null, "return_tone": null, "trend_line": "775.7 TWD", "fair_value": "473.3 TWD", "activity_pressure": "0.95", "relative_leadership": "51.73", "volume": "18.6M", "trend_backdrop": null}, {"week": "2026-07-31", "close": "1,060 TWD", "return": null, "return_tone": null, "trend_line": "749.2 TWD", "fair_value": "467.1 TWD", "activity_pressure": "1.11", "relative_leadership": "34.50", "volume": "14.5M", "trend_backdrop": null}, {"week": "2026-07-24", "close": "1,135 TWD", "return": null, "return_tone": null, "trend_line": "728.6 TWD", "fair_value": "462.2 TWD", "activity_pressure": "1.39", "relative_leadership": "43.26", "volume": "11.0M", "trend_backdrop": null}, {"week": "2026-07-17", "close": "1,195 TWD", "return": null, "return_tone": null, "trend_line": "705.6 TWD", "fair_value": "456.7 TWD", "activity_pressure": "1.60", "relative_leadership": "55.47", "volume": "16.6M", "trend_backdrop": null}, {"week": "2026-07-10", "close": "1,285 TWD", "return": null, "return_tone": null, "trend_line": "680.8 TWD", "fair_value": "450.9 TWD", "activity_pressure": "1.64", "relative_leadership": "58.80", "volume": "17.3M", "trend_backdrop": null}, {"week": "2026-07-03", "close": "1,256 TWD", "return": null, "return_tone": null, "trend_line": "653.4 TWD", "fair_value": "444.4 TWD", "activity_pressure": "1.66", "relative_leadership": "51.97", "volume": "17.7M", "trend_backdrop": null}, {"week": "2026-06-26", "close": "1,040 TWD", "return": null, "return_tone": null, "trend_line": "627.0 TWD", "fair_value": "438.1 TWD", "activity_pressure": "1.57", "relative_leadership": "33.11", "volume": "14.2M", "trend_backdrop": null}, {"week": "2026-06-19", "close": "954.5 TWD", "return": null, "return_tone": null, "trend_line": "606.4 TWD", "fair_value": "433.1 TWD", "activity_pressure": "1.49", "relative_leadership": "17.72", "volume": "9.7M", "trend_backdrop": null}, {"week": "2026-06-12", "close": "854.6 TWD", "return": null, "return_tone": null, "trend_line": "589.0 TWD", "fair_value": "428.8 TWD", "activity_pressure": "1.25", "relative_leadership": "10.97", "volume": "21.5M", "trend_backdrop": null}, {"week": "2026-06-05", "close": "843.8 TWD", "return": null, "return_tone": null, "trend_line": "575.5 TWD", "fair_value": "425.1 TWD", "activity_pressure": "0.98", "relative_leadership": "7.42", "volume": "16.4M", "trend_backdrop": null}, {"week": "2026-05-29", "close": "837.5 TWD", "return": null, "return_tone": null, "trend_line": "562.4 TWD", "fair_value": "421.4 TWD", "activity_pressure": "0.62", "relative_leadership": "7.39", "volume": "19.9M", "trend_backdrop": null}, {"week": "2026-05-22", "close": "729.4 TWD", "return": null, "return_tone": null, "trend_line": "549.5 TWD", "fair_value": "417.7 TWD", "activity_pressure": "0.16", "relative_leadership": "-1.01", "volume": "15.4M", "trend_backdrop": null}, {"week": "2026-05-15", "close": "743.8 TWD", "return": null, "return_tone": null, "trend_line": "540.7 TWD", "fair_value": "414.8 TWD", "activity_pressure": "-0.12", "relative_leadership": "3.49", "volume": "28.9M", "trend_backdrop": null}, {"week": "2026-05-08", "close": "652.0 TWD", "return": null, "return_tone": null, "trend_line": "532.0 TWD", "fair_value": "412.0 TWD", "activity_pressure": "-0.34", "relative_leadership": "-10.42", "volume": "13.5M", "trend_backdrop": null}], "intelligence": {"rating": "Positive", "rating_tone": "positive", "overall_score": "67", "primary_driver": {"label": "Indicator analysis", "score": 89.72916666666666, "score_label": "90", "tone": "positive", "summary": "Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 11/12.", "detail": "Activity pressure 0.98; No reversal markers", "metric": "90/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.45}, "primary_conflict": {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, "options_tone": "neutral", "options": null, "evidence": [{"label": "Weekly tape", "score": 68.80202526449729, "score_label": "69", "tone": "positive", "summary": "Trend, activity pressure, participation, and risk combine to a 69/100 tape read.", "detail": "", "metric": "69/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.6}, {"label": "Indicator analysis", "score": 89.72916666666666, "score_label": "90", "tone": "positive", "summary": "Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 11/12.", "detail": "Activity pressure 0.98; No reversal markers", "metric": "90/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.45}, {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, {"label": "Sentiment", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "Weighted news tone is neutral across 0 relevant articles.", "detail": "", "metric": "50/100", "url": "/sentiment/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 0.95}, {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}], "positives": [{"label": "Indicator analysis", "score": 89.72916666666666, "score_label": "90", "tone": "positive", "summary": "Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 11/12.", "detail": "Activity pressure 0.98; No reversal markers", "metric": "90/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.45}, {"label": "Weekly tape", "score": 68.80202526449729, "score_label": "69", "tone": "positive", "summary": "Trend, activity pressure, participation, and risk combine to a 69/100 tape read.", "detail": "", "metric": "69/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.6}], "negatives": [], "conclusion": ["The strongest supporting evidence is indicator analysis: Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 11/12.", "The main constraint is patient capital: Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "The combined read is constructive, but confirmation should still come from follow-through in price, volume, and group structure."], "weekly_changes": [{"label": "Price follow-through", "value": "17.0%", "detail": "Latest completed week; four-week move -3.5%.", "tone": "positive", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/"}, {"label": "Indicator stack", "value": "92/64", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "positive", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}, {"label": "News sentiment", "value": "50/100", "detail": "0 relevant articles in the latest sentiment read.", "tone": "neutral", "url": "/sentiment/adbc8547-2152-4123-86b9-f5e77c6920f1/"}]}, "investor_view": {"stance": "Mixed setup", "stance_tone": "neutral", "setup_score": "70", "bottom_line": "The weekly trend is active. Price is 59.9% above the Trend Line and sits at 82.9% of its 52-week range. The latest completed week returned 17.0%, after a -3.5% four-week move. The latest news-sentiment score is 50/100.", "price_summary": "The weekly trend is active. Price is 59.9% above the Trend Line and sits at 82.9% of its 52-week range. The latest completed week returned 17.0%, after a -3.5% four-week move.", "volume_summary": "Latest weekly volume is 1.1x the 13-week average. Participation is around or above normal and provides reasonable confirmation.", "momentum_summary": "Performance is -3.5% over four weeks, 66.7% over 12 weeks, and 201.6% over one year. The current trend has remained active for 44 consecutive weeks.", "fundamentals": {"available": false, "summary": "A published fundamentals and factor snapshot is not available for this company.", "rank_scores": [], "groups": []}, "weekly_change": [{"label": "Price follow-through", "value": "17.0%", "detail": "Latest completed week; four-week move -3.5%.", "tone": "positive", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/"}, {"label": "Indicator stack", "value": "92/64", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "positive", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}, {"label": "News sentiment", "value": "50/100", "detail": "0 relevant articles in the latest sentiment read.", "tone": "neutral", "url": "/sentiment/adbc8547-2152-4123-86b9-f5e77c6920f1/"}], "strengths": ["The trend backdrop is active with a 44-week active streak.", "Price is above the Trend Line, keeping the weekly tape constructive.", "Price is above Fair Value, showing premium demand versus the model.", "Activity pressure is positive on the latest completed week."], "risks": ["No major top-level risk cluster is currently dominant."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade.", "A volume ratio above 1.5x would show stronger participation in the next move."], "evidence": {"weekly_tape": {"label": "Weekly tape", "score": 68.80202526449729, "score_label": "69", "tone": "positive", "summary": "Trend, activity pressure, participation, and risk combine to a 69/100 tape read.", "detail": "", "metric": "69/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.6}, "indicator_analysis": {"label": "Indicator analysis", "score": 89.72916666666666, "score_label": "90", "tone": "positive", "summary": "Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 11/12.", "detail": "Activity pressure 0.98; No reversal markers", "metric": "90/100", "url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 1.45}, "factors": {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, "patient_capital": {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, "sentiment": {"label": "Sentiment", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "Weighted news tone is neutral across 0 relevant articles.", "detail": "", "metric": "50/100", "url": "/sentiment/adbc8547-2152-4123-86b9-f5e77c6920f1/", "available": true, "weight": 0.95}, "insiders": {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, "earnings": {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}}, "section_nav": [{"id": "overview", "label": "Overview"}, {"id": "price-action", "label": "Price"}, {"id": "volume-demand", "label": "Volume"}, {"id": "momentum", "label": "Momentum"}, {"id": "fundamentals", "label": "Fundamentals"}, {"id": "ownership-flow", "label": "Ownership & Flow"}, {"id": "catalysts-risk", "label": "Catalysts & Risk"}, {"id": "peer-context", "label": "Peer Context"}, {"id": "weekly-data", "label": "Weekly Data"}]}, "chart_url": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/", "api_path": "/terminal/adbc8547-2152-4123-86b9-f5e77c6920f1/report/api/"}