{"ticker": {"uuid": "d613420e-7080-43b0-b7e0-435c91da54a9", "symbol": "2162", "name": "Keymed Biosciences Inc.", "exchange": "HKG", "asset_type": "equity"}, "latest_week": "2026-06-12", "summary": "2162 closed the latest completed week at 58.60 HKD. The 4-week return is -11.3% and the 12-week return is 14.9%. The trend backdrop is inactive, with activity pressure at -0.11.", "description": "Keymed Biosciences Inc., a biotechnology company, engages in the discovery and development of biological therapies in the autoimmune and oncology therapeutic areas in Mainland China, the United States, and the United Kingdom. The company develops Kangyueda for the treatment of moderate-to-severe atopic dermatitis in adults, chronic rhinosinusitis with nasal polyps, and seasonal allergic rhinitis; CMG901/AZD0901, an antibody drug conjugate for treatment of advanced solid tumors; CM512, a TSLP x IL-13 bispecific antibody in Phase I clinical study; and CM518D1, an antibody drug conjugate drug in open-label Phase I/II clinical trial. It is also developing CM336, a CMA x CD3 bispecific antibody in an open-label Phase I/II clinical study for the treatment of patients with relapsed or refractory multiple myeloma; CM313 in Phase II clinical study in subjects with primary immune thrombocytopenia; CM383, an A\u00df protofibrils antibody in Phase Ib clinical study; and CM559, a N3pG A\u00df antibody in Phase I clinical study. In addition, the company is involved in the development of CM350, a GPC3 x CD3 bispecific antibody in Phase I/II clinical study; CM326, a TSLP antibody; CM355/ICP-B02/PRO-203, a CD20 x CD3 bispecific antibody; and CM369/ICP-B05, an anti-C-C motif chemokine receptor 8 monoclonal antibody. It has an out-licence agreement with Belenos Biosciences, Inc.; Platina Medicines Ltd; Prolium Biosciences, Inc.; and Timberlyne Therapeutics, Inc. The company was formerly known as 2Health Biosciences, Inc. Keymed Biosciences Inc. was founded in 2016 and is headquartered in Chengdu, the People's Republic of China.", "setup_signature": "Risk-first tape", "composite_score": "35", "kpis": [{"label": "Latest Close", "value": "58.60 HKD", "hint": "2026-06-12"}, {"label": "1W Return", "value": "0.3%", "tone": "positive", "hint": "latest completed week"}, {"label": "4W Return", "value": "-11.3%", "tone": "negative", "hint": "short-term follow-through"}, {"label": "12W Return", "value": "14.9%", "tone": "positive", "hint": "quarterly tape"}, {"label": "Trend Breadth", "value": "57.7%", "hint": "30 of 52 weeks active"}, {"label": "Volume Ratio", "value": "1.0x", "hint": "vs 13-week average"}], "classification": {"exchange": "HKG", "country": "HK", "sector": "Healthcare", "industry": "Biotechnology", "currency": "HKD", "market_cap": "17.9B"}, "price": {"trend_line": "60.55 HKD", "fair_value": "47.52 HKD", "vs_trend": "-3.2%", "vs_fair_value": "23.3%", "high_52": "81.85 HKD", "low_52": "43.80 HKD", 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"return_tone": "negative", "volume_height": 40.048211040772166, "volume": "9.3M"}, {"week": "5 Jun", "return": -5.501613357631283, "return_label": "-5.5%", "return_tone": "negative", "volume_height": 49.9606830857071, "volume": "11.7M"}, {"week": "12 Jun", "return": 0.3424588923815426, "return_label": "0.3%", "return_tone": "positive", "volume_height": 48.16721060598343, "volume": "11.2M"}], "insights": [{"label": "Participation", "value": "1.0x", "detail": "Latest volume versus the 13-week average.", "tone": "neutral"}, {"label": "Baseline", "value": "11.5M", "detail": "13-week average volume.", "tone": "neutral"}, {"label": "One-year base", "value": "12.5M", "detail": "52-week average volume.", "tone": "neutral"}]}, "risk": {"volatility_13": "8.2%", "volatility_52": "7.2%", "downside_weeks": 30, "upside_weeks": 22, "downside_breadth": "57.7%", "average_gain": "7.1%", "average_loss": "-4.1%", "buckets": [{"label": "Strong gains", "count": 5, "share": 19.230769230769234, "share_label": "19.2%", "tone": "positive"}, {"label": "Modest gains", "count": 5, "share": 19.230769230769234, "share_label": "19.2%", "tone": "positive"}, {"label": "Flat weeks", "count": 0, "share": 0.0, "share_label": "0.0%", "tone": "neutral"}, {"label": "Modest losses", "count": 9, "share": 34.61538461538461, "share_label": "34.6%", "tone": "negative"}, {"label": "Sharp losses", "count": 7, "share": 26.923076923076923, "share_label": "26.9%", "tone": "negative"}], "insights": [{"label": "Recent vol", "value": "8.2%", "detail": "13-week weekly-return volatility.", "tone": "neutral"}, {"label": "Base vol", "value": "7.2%", "detail": "52-week weekly-return volatility.", "tone": "neutral"}, {"label": "Up/down split", "value": "22/30", "detail": "Count of positive and negative weeks in the 52-week window.", "tone": "negative"}, {"label": "Average skew", "value": "7.1% / -4.1%", "detail": "Average positive week versus average negative week.", "tone": "neutral"}]}, "signals": [{"label": "Trend backdrop", "value": "Inactive", "tone": "negative"}, {"label": "Activity pressure", "value": "No fresh buy", "tone": "neutral"}, {"label": "Price vs Trend", "value": "-3.2%", "tone": "negative"}, {"label": "Volume", "value": "1.0x", "tone": "neutral"}], "opportunities": ["Price is above Fair Value, showing premium demand versus the model.", "Activity pressure is constructive, supporting the smart-money activity read."], "risks": ["The trend backdrop is inactive, so price action has not confirmed a constructive regime.", "Price is below the Trend Line, which keeps downside pressure in focus.", "Activity pressure is negative, which weakens the current setup.", "2 reversal markers appear in the recent smart-money tape.", "The share remains more than 20% below its 52-week high."], "watch_points": ["Trend Line remains the key weekly regime level.", "Activity pressure is the gauge to monitor for confirmation or fade.", "A volume ratio above 1.5x would show stronger participation in the next move."], "recent_rows": [{"week": "2026-06-12", "close": "58.60 HKD", "return": null, "return_tone": null, "trend_line": "60.55 HKD", "fair_value": "47.52 HKD", "activity_pressure": "-0.11", "relative_leadership": "-1.04", "volume": "11.2M", "trend_backdrop": null}, {"week": "2026-06-05", "close": "58.40 HKD", "return": null, "return_tone": null, "trend_line": "60.61 HKD", "fair_value": "47.43 HKD", "activity_pressure": "0.12", "relative_leadership": "-2.04", "volume": "11.7M", "trend_backdrop": null}, {"week": "2026-05-29", "close": "61.80 HKD", "return": null, "return_tone": null, "trend_line": "60.58 HKD", "fair_value": "47.33 HKD", "activity_pressure": "0.36", "relative_leadership": "3.03", "volume": "9.3M", "trend_backdrop": null}, {"week": "2026-05-22", "close": "62.80 HKD", "return": null, "return_tone": null, "trend_line": "60.53 HKD", "fair_value": "47.21 HKD", "activity_pressure": "0.62", "relative_leadership": "3.43", "volume": "9.9M", "trend_backdrop": null}, {"week": "2026-05-15", "close": "66.05 HKD", "return": null, "return_tone": null, "trend_line": "60.40 HKD", "fair_value": "47.14 HKD", "activity_pressure": "0.95", "relative_leadership": "7.94", "volume": "10.6M", "trend_backdrop": null}, {"week": "2026-05-08", "close": "71.95 HKD", "return": null, "return_tone": null, "trend_line": "60.30 HKD", "fair_value": "47.08 HKD", "activity_pressure": "1.24", "relative_leadership": "16.42", "volume": "4.1M", "trend_backdrop": null}, {"week": "2026-05-01", "close": "75.55 HKD", "return": null, "return_tone": null, "trend_line": "60.24 HKD", "fair_value": "47.01 HKD", "activity_pressure": "1.40", "relative_leadership": "26.09", "volume": "4.3M", "trend_backdrop": null}, {"week": "2026-04-24", "close": "76.00 HKD", "return": null, "return_tone": null, "trend_line": "60.21 HKD", "fair_value": "46.93 HKD", "activity_pressure": "1.54", "relative_leadership": "26.69", "volume": "14.9M", "trend_backdrop": null}, {"week": "2026-04-17", "close": "79.25 HKD", "return": null, "return_tone": null, "trend_line": "60.02 HKD", "fair_value": "46.84 HKD", "activity_pressure": "1.46", "relative_leadership": "32.29", "volume": "16.0M", "trend_backdrop": null}, {"week": "2026-04-10", "close": "75.00 HKD", "return": null, "return_tone": null, "trend_line": "59.78 HKD", "fair_value": "46.73 HKD", "activity_pressure": "0.89", "relative_leadership": "27.60", "volume": "8.8M", "trend_backdrop": null}, {"week": "2026-04-03", "close": "71.35 HKD", "return": null, "return_tone": null, "trend_line": "59.81 HKD", "fair_value": "46.71 HKD", "activity_pressure": "0.44", "relative_leadership": "26.00", "volume": "23.3M", "trend_backdrop": null}, {"week": "2026-03-27", "close": "60.55 HKD", "return": null, "return_tone": null, "trend_line": "60.05 HKD", "fair_value": "46.64 HKD", "activity_pressure": "-0.02", "relative_leadership": "8.32", "volume": "19.5M", "trend_backdrop": null}, {"week": "2026-03-20", "close": "51.00 HKD", "return": null, "return_tone": null, "trend_line": "60.34 HKD", "fair_value": "46.63 HKD", "activity_pressure": "-0.45", "relative_leadership": "-9.55", "volume": "6.2M", "trend_backdrop": null}, {"week": "2026-03-13", "close": "52.60 HKD", "return": null, "return_tone": null, "trend_line": "61.07 HKD", "fair_value": "46.67 HKD", "activity_pressure": "-0.48", "relative_leadership": "-7.08", "volume": "6.9M", "trend_backdrop": null}], "intelligence": {"rating": "Neutral", "rating_tone": "neutral", "overall_score": "49", "primary_driver": {"label": "Indicator analysis", "score": 65.40277777777777, "score_label": "65", "tone": "positive", "summary": "Latest 12-week confirmation: trend 7/12, activity pressure 10/12, relative leadership 10/12.", "detail": "Activity pressure 0.72; 2 reversal markers", "metric": "65/100", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "available": true, "weight": 1.45}, "primary_conflict": {"label": "Weekly tape", "score": 35.32858405851975, "score_label": "35", "tone": "negative", "summary": "Trend, activity pressure, participation, and risk combine to a 35/100 tape read.", "detail": "", "metric": "35/100", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "available": true, "weight": 1.6}, "options_tone": "neutral", "options": null, "evidence": [{"label": "Weekly tape", "score": 35.32858405851975, "score_label": "35", "tone": "negative", "summary": "Trend, activity pressure, participation, and risk combine to a 35/100 tape read.", "detail": "", "metric": "35/100", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "available": true, "weight": 1.6}, {"label": "Indicator analysis", "score": 65.40277777777777, "score_label": "65", "tone": "positive", "summary": "Latest 12-week confirmation: trend 7/12, activity pressure 10/12, relative leadership 10/12.", "detail": "Activity pressure 0.72; 2 reversal markers", "metric": "65/100", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "available": true, "weight": 1.45}, {"label": "Factors", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No published factor snapshot is available yet.", "detail": "", "metric": "50/100", "url": "/factors/", "available": false, "weight": 0}, {"label": "Patient Capital", "score": 48.0, "score_label": "48", "tone": "neutral", "summary": "Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.", "detail": "No recent buy signal", "metric": "Quiet", "url": "/patient-capital/", "available": true, "weight": 1}, {"label": "Sentiment", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No sentiment snapshot is stored yet.", "detail": "", "metric": "50/100", "url": "/sentiment/", "available": false, "weight": 0}, {"label": "Insiders", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No recent insider transaction evidence is stored.", "detail": "", "metric": "50/100", "url": "/insider-activity/", "available": false, "weight": 0}, {"label": "Earnings", "score": 50.0, "score_label": "50", "tone": "neutral", "summary": "No stored earnings event is currently attached to this ticker.", "detail": "", "metric": "50/100", "url": "/earnings-calendar/", "available": false, "weight": 0}], "positives": [{"label": "Indicator analysis", "score": 65.40277777777777, "score_label": "65", "tone": "positive", "summary": "Latest 12-week confirmation: trend 7/12, activity pressure 10/12, relative leadership 10/12.", "detail": "Activity pressure 0.72; 2 reversal markers", "metric": "65/100", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "available": true, "weight": 1.45}], "negatives": [{"label": "Weekly tape", "score": 35.32858405851975, "score_label": "35", "tone": "negative", "summary": "Trend, activity pressure, participation, and risk combine to a 35/100 tape read.", "detail": "", "metric": "35/100", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "available": true, "weight": 1.6}], "conclusion": ["The strongest supporting evidence is indicator analysis: Latest 12-week confirmation: trend 7/12, activity pressure 10/12, relative leadership 10/12.", "The main constraint is weekly tape: Trend, activity pressure, participation, and risk combine to a 35/100 tape read.", "The combined read is balanced, making the next change in trend, sentiment, or options pressure especially important."], "weekly_changes": [{"label": "Price follow-through", "value": "0.3%", "detail": "Latest completed week; four-week move -11.3%.", "tone": "positive", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/"}, {"label": "Indicator stack", "value": "32/39", "detail": "Trend and activity pressure are weighted against the latest 12-week confirmation window.", "tone": "negative", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/"}, {"label": "Trend backdrop", "value": "Active", "detail": "The trend backdrop defines the current weekly regime.", "tone": "positive", "url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/"}, {"label": "Patient Capital", "value": "Quiet", "detail": "Activity-pressure buy-signal status for institutional accumulation timing.", "tone": "neutral", "url": "/patient-capital/"}]}, "chart_url": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/", "api_path": "/terminal/d613420e-7080-43b0-b7e0-435c91da54a9/report/api/"}