Weekly Report - Soleno Therapeutics, Inc. (SLNO)

Entity & Brand

Company	Soleno Therapeutics, Inc.
Ticker	SLNO
Exchange	NASDAQ
Weeks Used	8

Signals Snapshot

8-week window ?

No signals in this window.

How to read this section

Left column describes the week the signal was generated (historical context). Right column shows performance and posture since that signal to the present. MFE ? and MAE ? quantify upside capture vs downside risk after the signal.

Price Overview

Tiles ?

Metric	Signal	Value	Notes
Price Window	Negative	-36.35% over 8w	Endpoint return across the selected window.
Return Volatility	Negative	4.14%	Std dev of weekly returns — low is steadier, high is whipsaw-prone.
Volume Trend	Positive	Rising	Slope of weekly volume across the window.
Vs 8w High	Negative	-36.35%	Distance to the prior-window high (latest week excluded).
Price vs MAs	Negative	Below

Trend Overview

Metric	Signal	Value
Gauge Reading	Neutral	65.2/100
Direction	Negative	Falling
Acceleration	Negative	decelerating
Trend State	Neutral	Uptrend at Risk
Momentum Drawdown	Negative	21.9 pts from 8w peak

Trend State: Uptrend at Risk — gauge 65.2/100 — 8w slope -2.78; ST slope -4.69 pts/wk — drawdown 21.9 pts from peak ?

Distribution at highs 4/4 (100.0%)

Weekly Price Action

8 weeks ?

Week ending	Open	High	Low	Close	Change %	Volume (MA) Trend
Fri, 19 Sep 2025	56.64	56.87	54.54	54.74	-3.35%
Fri, 12 Sep 2025	56.04	56.17	52.37	53.62	-4.32%
Fri, 5 Sep 2025	69.82	70.06	67.51	69.77	-0.07%
Fri, 29 Aug 2025	67.84	68.90	66.61	67.67	-0.25%
Fri, 22 Aug 2025	70.23	70.74	66.29	68.41	-2.59%
Fri, 15 Aug 2025	66.30	72.81	63.46	71.63	8.04%
Fri, 8 Aug 2025	77.60	82.57	77.33	82.35	6.12%
Fri, 1 Aug 2025	85.58	88.61	85.14	86.00	0.49%	—

Price Narrative

Stands Out	No highlights available.
What to Watch	No watch items available.

Trend Narrative

Stands Out	Trend focus for week ending Fri, 19 Sep 2025. Gauge: 65.2/100; slope -2.78 pts/wk; short-term -4.69 pts/wk; decelerating. Gauge volatility: normal. Momentum drawdown from 8w peak: 21.9 pts. High-regime (0.80–1.00) downticks 4/4 (100.0%), bias: Distributing.
What to Watch	How to read this — Gauge is elevated but momentum is rolling over; topping risk is rising.

All Price Analysis

Complete dump of monthly_analysis.series & monthly_analysis.diagnostics

Series
Close Price	Change Pct: -36.348837209302324, Slope: -4.390357142857143
Change Percent	Vol: 4.137116862925194, Slope: -1.2032142857142856
Volume	Slope: 108507.14285714286, Z Last: 0.5550597893116946
Deviation From Baseline	Last: 0.52738, Z Last: -1.1151183420263777, Slope: -0.2761260714285715
Diagnostics
Volume Trend	rising
Close Vs Recent High Pct	-36.348837209302324
Conv Div	divergence
Momentum Trend	weakening
Last Trend Label	Bullish
Close Vs Recent Low Pct	2.0887728459530113
Ma Stack	mixed
Cross 4 8	none
Price Vs Ma	below
Baseline Deviation	0.52738
Baseline Dir	narrowing

What does it mean?

8-week price move: -36.35%. Weekly return volatility: 4.14%. Close is 36.35% below the prior-window 8-week high. and 2.09% above the prior-window 8-week low. Volume trend: rising. Latest week’s volume is 0.56σ from its 8-week average. Price/volume correlation (returns vs volume): 0.14. Price/volume correlation (returns vs volume change): 0.41. 26-week move: -24.14%. 52-week move: 11.83%. Price sits 0.53% above its medium-term baseline, and the distance is narrowing.
How to read this — Price slope is downward, indicating persistent supply pressure. Elevated weekly volatility increases whipsaw risk. Volume trend diverges from price — watch for fatigue or rotation. Distance to baseline is narrowing — reverting closer to its fair-value track. Price sits below key averages, keeping pressure on the tape.
Down-slope argues for patience; rallies can fade sooner unless participation improves. Because liquidity isn’t confirming, prefer evidence of fresh demand before chasing moves.

All Trend Analysis

Complete dump of trend_analysis.series & trend_analysis.diagnostics

Series
Trend Pos	Avg: 78.982875, Med: 80.059, Rng: (65.238, 87.129), Vol: 6.670277213832646, Slope: -2.78277380952381, Last: 65.238
Diagnostics
Last Pos	65.238
Vol Band	normal
Acceleration Label	Decelerating
Last Label	Neutral
State Label	Uptrend at Risk
Slope 8W	-2.78277380952381
Slope Short	-4.687299999999999
Accel Value	-0.7998214285714279
Drawdown From Peak Pts	21.891000000000005
Time In Bull	8
Time In Bear	0
Time In Mid	0
High Breakdown Recent	False
Midline Failure Recent	False
Bear Control Recent	False
Recovery Mid Recent	False
Recovery Bull Recent	False
Acc Upticks	0
Acc Opportunities	0
Acc Rate	None
Acc Longest Streak	0
Dist Downticks	4
Dist Opportunities	4
Dist Rate	1.0
Dist Longest Streak	3
Low Regime Bias	Mixed/None
High Regime Bias	Distributing

What does it mean?

Trend focus for week ending Fri, 19 Sep 2025. Gauge: 65.2/100; slope -2.78 pts/wk; short-term -4.69 pts/wk; decelerating. Gauge volatility: normal. Momentum drawdown from 8w peak: 21.9 pts. High-regime (0.80–1.00) downticks 4/4 (100.0%), bias: Distributing.
How to read this — Gauge is elevated but momentum is rolling over; topping risk is rising.
Stay alert: protect gains or seek confirmation before adding risk.

Final Conclusion

Verdict	Negative
Stars	★☆☆☆☆
Summary	Price window: -36. Trend: Uptrend at Risk; gauge 65. In combination, liquidity diverges from price.
Strengths	None listed.
Watch-outs	High-level but rolling over (topping risk) Momentum is weak/falling Price is not above key averages Liquidity diverges from price

Disclaimer. This report is provided for educational and informational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Past performance is not indicative of future results. Markets involve risk, including possible loss of principal. Always perform your own research and consider consulting a qualified financial professional before making investment decisions.