FULC NASDAQ Week ended 31 Jul 2026

Weekly Investor Report

Fulcrum Therapeutics Inc · Healthcare · Biotechnology

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Latest close 3.58 USD
-3.8% latest week
Weekly setup

Weak trend

The weekly trend is not active. Price is -48.8% below the Trend Line and sits at 5.8% of its 52-week range. The latest completed week returned -3.8%, after a -6.8% four-week move. The latest factor snapshot indicates quality is middle-of-the-pack; growth is moderate; valuation is neither clearly cheap nor expensive. Options positioning is volatility with 52/100 conviction, while the latest news-sentiment score is 43/100. Near-term considerations: volume confirmation is below normal; earnings are due in 2d.

Setup score 19 out of 100
Latest Close 3.58 USD 31 Jul 2026
1W Return -3.8% latest completed week
4W Return -6.8% short-term follow-through
12W Return -48.9% quarterly tape
Trend Breadth 57.7% 30 of 52 weeks active
Volume Ratio 0.6x vs 13-week average
What is working
  • No strong opportunity cluster is confirmed yet; monitor trend and activity pressure.
What could go wrong
  • The trend backdrop is inactive, so price action has not confirmed a constructive regime.
  • Price is below the Trend Line, which keeps downside pressure in focus.
  • Price is below Fair Value, so the market is still discounting the latest tape.
  • Activity pressure is negative, which weakens the current setup.
What to watch next
  • Trend Line remains the key weekly regime level.
  • Activity pressure is the gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through -3.8% Latest completed week; four-week move -6.8%. Indicator stack 32/23 Trend and activity pressure are weighted against the latest 12-week confirmation window. Trend backdrop Active The trend backdrop defines the current weekly regime. Patient Capital Quiet Activity-pressure buy-signal status for institutional accumulation timing. Options pressure Volatility 52/100 conviction; expected move 20.5%. News sentiment 43/100 59 relevant articles in the latest sentiment read. Event risk 2d Next report is scheduled for 04 Aug 2026; event risk rises as the date approaches.
01 · Price action

Where price is—and whether the trend supports it

The weekly trend is not active. Price is -48.8% below the Trend Line and sits at 5.8% of its 52-week range. The latest completed week returned -3.8%, after a -6.8% four-week move.

Study the full chart

52-week price path

Price vs Trend Line and Fair Value
Price Trend Line Fair Value
02 · Volume and demand

Is real participation confirming the move?

Latest weekly volume is 0.6x the 13-week average. Participation is below its recent norm, so price strength is not receiving full volume confirmation.

26-week volume confirmation

Bar height shows volume; colour shows the weekly price direction
6 Feb 13 Feb 20 Feb 27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 3 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun 19 Jun 26 Jun 3 Jul 10 Jul 17 Jul 24 Jul 31 Jul
Up week Down week
Demand beneath price

Activity pressure and institutional-style signals

These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.

Activity pressure path

Latest 0.0312-week average 0.04

12-week confirmation

Trend active0/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure0/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership0/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.03Current proprietary activity-pressure read.
Buy signals0Accumulation signal count in the latest 12 weeks.
Reversal markers0No reversal markers

No recent accumulation markers. No reversal markers.

03 · Momentum and leadership

Is performance persistent—and is the stock leading?

Performance is -6.8% over four weeks, -48.9% over 12 weeks, and -47.6% over one year. The current trend has remained active for 0 consecutive weeks.

Performance by holding period

1W-3.8%
4W-6.8%
12W-48.9%
26W-66.6%
52W-47.6%
Active trend streak0 weeks
Active weeks in one year30
Trend breadth57.7%

Activity pressure vs relative leadership

Activity pressureRelative leadership
Pressure-1.30Latest activity-pressure read.
Pressure change-49.1%Four-week change in activity pressure.
Leadership-58.85Latest relative-leadership reading.
RS change1.0%Four-week change in relative leadership.
04 · Fundamentals and valuation

What investors are paying for—and the quality behind it

The latest factor snapshot indicates quality is middle-of-the-pack; growth is moderate; valuation is neither clearly cheap nor expensive.

Open full factor analysis
Factor week 26 Jul 2026 Financial statements through 31 Mar 2026 Field coverage 67% Model confidence 64%

Relative factor standing

Higher display scores are better. Each score is converted from the underlying universe rank, where rank 1 is best.

Overall factor strength60/100Blend of value, momentum, and quality. Underlying universe rank 41; rank 1 is best.
Value54/100Relative valuation strength. Underlying universe rank 47; rank 1 is best.
Quality53/100Profitability and accounting quality. Underlying universe rank 48; rank 1 is best.
Momentum55/100Medium-term price momentum. Underlying universe rank 46; rank 1 is best.
Growth55/100Revenue and earnings growth. Underlying universe rank 46; rank 1 is best.
How to read this

Quality and valuation are separate questions

A strong company can still carry a demanding valuation. This report shows profitability, growth, balance-sheet strength, and the price paid for those characteristics separately.

Valuation

How much investors are paying for earnings, sales, and cash flow.

P/E
-
Price divided by trailing earnings.
Price / sales
-
Market value relative to trailing revenue.
EV / EBITDA
-
Enterprise value relative to operating cash earnings.
Free-cash-flow yield
-31.1%
Free cash flow as a share of enterprise value.

Business quality

Margins and the return generated on invested capital.

Gross margin
-
Gross profit retained from each unit of revenue.
Operating margin
-
Operating profit retained from revenue.
Free-cash-flow margin
-
Free cash flow generated from revenue.
Return on invested capital
-19.8%
Operating return generated on invested capital.

Growth and financial strength

Recent business growth and accounting strength.

Revenue growth
-
Latest one-year revenue growth.
EPS growth
-
Latest one-year earnings-per-share growth.
Free-cash-flow growth
-884.7%
Latest one-year free-cash-flow growth.
Piotroski F-score
3/9
Nine-point accounting-strength checklist.

Shareholder return and balance sheet

Cash returned to owners and financial leverage.

Dividend yield
-
Cash dividends relative to market value.
Buyback yield
-66.4%
Net share repurchases relative to market value.
Shareholder yield
-66.4%
Dividend yield plus net buyback yield.
Net debt / EBITDA
0.6x
Balance-sheet debt relative to operating cash earnings.
05 · Ownership, options, and sentiment

What other market participants are doing

Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.

Options positioningVolatility

FULC shows volatility options pressure with a 53/100 conviction score, put-call volume ratio of 0.03, expected move of 20.5%, and Sharemaestro trend signal inactive.

Conviction53/100
Expected move20.5%
Put/call volume0.03
Pressure100
Speculation4
Volatility96
Trend agreement0
Open options detail
Insider activity15 / 1

15 acquisitions and 1 disposals in the latest 180-day insider tape.

Acquisitions / disposals over the latest 180 days. Insider activity is context, not a stand-alone signal.
News sentiment43/100

Weighted news tone is neutral across 59 relevant articles.

5 positive · 38 neutral · 16 negative
Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal
06 · Catalysts and risk

What can move the shares—and how volatile the path has been

Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.

Next earnings2dNext report is scheduled for 04 Aug 2026; event risk rises as the date approaches.
Options expected move20.5%Nearest-chain priced movement where available.
52-week drawdown-77.3%Distance below the 52-week high.
13-week volatility13.1%Standard deviation of weekly returns.

Weekly gains and losses

Latest 26 completed weeks

Each bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.

Weeks higher10 of 2616 weeks finished lower.
Best week+19.5%Week of 3 Apr.
Worst week-46.7%Week of 5 Jun.
Latest week-3.8%Week of 31 Jul.

Shape of recent returns

Strong gains6
Modest gains4
Flat weeks0
Modest losses4
Sharp losses12
Recent vol13.1%13-week weekly-return volatility.
Base vol13.1%52-week weekly-return volatility.
Up/down split22/29Count of positive and negative weeks in the 52-week window.
Average skew10.0% / -8.2%Average positive week versus average negative week.
07 · Sector and peer context

Is this stock leading—or simply moving with its group?

Sector and industry breadth distinguish company-specific strength from a broad group move.

08 · Evidence and weekly data

The underlying research record

Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.

Weekly tape22/100

Trend, activity pressure, participation, and risk combine to a 22/100 tape read.

 Indicator analysis9/100

Latest 12-week confirmation: trend 0/12, activity pressure 0/12, relative leadership 0/12.

Activity pressure 0.03; No reversal markers Factors55/100

O'Shaughnessy factor stack blends value, quality, momentum, and confidence.

Buyback Yield rank 98; Small Cap Core rank 51 Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal Options36/100

FULC shows volatility options pressure with a 53/100 conviction score, put-call volume ratio of 0.03, expected move of 20.5%, and Sharemaestro trend signal inactive.

Volatility · Volatility expansion watch · Expected move 20.5% Sentiment43/100

Weighted news tone is neutral across 59 relevant articles.

Fulcrum Therapeutics: Buy It For The Strategic Reset (NASDAQ:FULC) Insiders15 / 1

15 acquisitions and 1 disposals in the latest 180-day insider tape.

 Earnings2d

Next report is scheduled for 04 Aug 2026; event risk rises as the date approaches.
WeekCloseReturnTrend LineFair ValuePressureLeadershipVolumeTrend
31 Jul 20263.58 USD-3.8%6.99 USD6.53 USD-1.30-58.857.6MOff
24 Jul 20263.72 USD1.9%7.24 USD6.53 USD-1.21-57.475.2MOff
17 Jul 20263.65 USD4.3%7.50 USD6.53 USD-1.07-59.459.1MOff
10 Jul 20263.50 USD-8.9%7.79 USD6.53 USD-0.94-63.2010.2MOff
3 Jul 20263.84 USD1.1%8.10 USD6.54 USD-0.87-59.457.3MOff
26 Jun 20263.80 USD2.7%8.27 USD6.53 USD-0.84-59.9417.4MOff
19 Jun 20263.70 USD7.2%8.51 USD6.53 USD-0.91-63.1525.9MOff
12 Jun 20263.45 USD-6.5%8.76 USD6.53 USD-1.03-65.1313.6MOff
5 Jun 20263.69 USD-46.7%8.94 USD6.52 USD-1.06-62.2850.3MOff
29 May 20266.92 USD5.3%9.07 USD6.52 USD-1.15-33.241.4MOff
22 May 20266.57 USD-1.8%9.13 USD6.50 USD-1.13-35.132.3MOff
15 May 20266.69 USD-4.6%9.22 USD6.47 USD-1.04-33.462.7MOff
8 May 20267.01 USD-4.8%9.29 USD6.45 USD-0.93-30.863.0MOff
1 May 20267.36 USD-6.1%9.36 USD6.43 USD-0.93-23.544.4MOff
How to use this report

This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.