MGTX NASDAQ Week ended 31 Jul 2026

Weekly Investor Report

MeiraGTx Holdings PLC · Healthcare · Biotechnology

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Latest close 11.79 USD
0.2% latest week
Weekly setup

Mixed setup

The weekly trend is active. Price is 25.9% above the Trend Line and sits at 59.2% of its 52-week range. The latest completed week returned 0.2%, after a -15.3% four-week move. The latest factor snapshot indicates quality is middle-of-the-pack; growth is moderate; valuation is neither clearly cheap nor expensive. Options positioning is mixed with 39/100 conviction, while the latest news-sentiment score is 52/100. Near-term considerations: volume confirmation is below normal; earnings are due in 11d.

Setup score 49 out of 100
Latest Close 11.79 USD 31 Jul 2026
1W Return 0.2% latest completed week
4W Return -15.3% short-term follow-through
12W Return 20.1% quarterly tape
Trend Breadth 71.2% 37 of 52 weeks active
Volume Ratio 0.6x vs 13-week average
What is working
  • The trend backdrop is active with a 15-week active streak.
  • Price is above the Trend Line, keeping the weekly tape constructive.
  • Price is above Fair Value, showing premium demand versus the model.
  • Activity pressure is positive on the latest completed week.
What could go wrong
  • Next-week expectancy is negative at 40.97% based on similar historical setup states.
  • 3 reversal markers appear in the recent smart-money tape.
  • The share remains more than 20% below its 52-week high.
What to watch next
  • Trend Line remains the key weekly regime level.
  • Activity pressure is the gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through 0.2% Latest completed week; four-week move -15.3%. Indicator stack 84/62 Trend and activity pressure are weighted against the latest 12-week confirmation window. Trend backdrop Active The trend backdrop defines the current weekly regime. Patient Capital Quiet Activity-pressure buy-signal status for institutional accumulation timing. Next-Week Expectancy Negative 40.97% Historical one-week expectancy contributes to the evidence score when direction is confirmed. Options pressure Mixed 39/100 conviction; expected move 34.0%. News sentiment 52/100 60 relevant articles in the latest sentiment read. Event risk 11d Next report is scheduled for 13 Aug 2026; event risk rises as the date approaches.
01 · Price action

Where price is—and whether the trend supports it

The weekly trend is active. Price is 25.9% above the Trend Line and sits at 59.2% of its 52-week range. The latest completed week returned 0.2%, after a -15.3% four-week move.

Study the full chart

52-week price path

Price vs Trend Line and Fair Value
Price Trend Line Fair Value
02 · Volume and demand

Is real participation confirming the move?

Latest weekly volume is 0.6x the 13-week average. Participation is below its recent norm, so price strength is not receiving full volume confirmation.

26-week volume confirmation

Bar height shows volume; colour shows the weekly price direction
6 Feb 13 Feb 20 Feb 27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 3 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun 19 Jun 26 Jun 3 Jul 10 Jul 17 Jul 24 Jul 31 Jul
Up week Down week
Demand beneath price

Activity pressure and institutional-style signals

These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.

Activity pressure path

Latest 0.8412-week average 0.65

12-week confirmation

Trend active12/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure12/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership9/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.84Current proprietary activity-pressure read.
Buy signals0Accumulation signal count in the latest 12 weeks.
Reversal markers33 reversal markers

No recent accumulation markers. 3 reversal markers.

03 · Momentum and leadership

Is performance persistent—and is the stock leading?

Performance is -15.3% over four weeks, 20.1% over 12 weeks, and 54.1% over one year. The current trend has remained active for 15 consecutive weeks.

Performance by holding period

1W0.2%
4W-15.3%
12W20.1%
26W54.9%
52W54.1%
Active trend streak15 weeks
Active weeks in one year37
Trend breadth71.2%

Activity pressure vs relative leadership

Activity pressureRelative leadership
Pressure0.79Latest activity-pressure read.
Pressure change-29.8%Four-week change in activity pressure.
Leadership23.37Latest relative-leadership reading.
RS change-45.5%Four-week change in relative leadership.
04 · Fundamentals and valuation

What investors are paying for—and the quality behind it

The latest factor snapshot indicates quality is middle-of-the-pack; growth is moderate; valuation is neither clearly cheap nor expensive.

Open full factor analysis
Factor week 26 Jul 2026 Financial statements through 31 Mar 2026 Field coverage 76% Model confidence 73%

Relative factor standing

Higher display scores are better. Each score is converted from the underlying universe rank, where rank 1 is best.

Overall factor strength52/100Blend of value, momentum, and quality. Underlying universe rank 49; rank 1 is best.
Value50/100Relative valuation strength. Underlying universe rank 51; rank 1 is best.
Quality48/100Profitability and accounting quality. Underlying universe rank 53; rank 1 is best.
Momentum50/100Medium-term price momentum. Underlying universe rank 51; rank 1 is best.
Growth50/100Revenue and earnings growth. Underlying universe rank 51; rank 1 is best.
How to read this

Quality and valuation are separate questions

A strong company can still carry a demanding valuation. This report shows profitability, growth, balance-sheet strength, and the price paid for those characteristics separately.

Valuation

How much investors are paying for earnings, sales, and cash flow.

P/E
-
Price divided by trailing earnings.
Price / sales
13.7x
Market value relative to trailing revenue.
EV / EBITDA
-
Enterprise value relative to operating cash earnings.
Free-cash-flow yield
1.7%
Free cash flow as a share of enterprise value.

Business quality

Margins and the return generated on invested capital.

Gross margin
91.6%
Gross profit retained from each unit of revenue.
Operating margin
-136.1%
Operating profit retained from revenue.
Free-cash-flow margin
23.7%
Free cash flow generated from revenue.
Return on invested capital
-
Operating return generated on invested capital.

Growth and financial strength

Recent business growth and accounting strength.

Revenue growth
131.1%
Latest one-year revenue growth.
EPS growth
-
Latest one-year earnings-per-share growth.
Free-cash-flow growth
-
Latest one-year free-cash-flow growth.
Piotroski F-score
5/9
Nine-point accounting-strength checklist.

Shareholder return and balance sheet

Cash returned to owners and financial leverage.

Dividend yield
-
Cash dividends relative to market value.
Buyback yield
-2.3%
Net share repurchases relative to market value.
Shareholder yield
-2.3%
Dividend yield plus net buyback yield.
Net debt / EBITDA
-0.2x
Balance-sheet debt relative to operating cash earnings.
05 · Ownership, options, and sentiment

What other market participants are doing

Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.

Options positioningMixed

MGTX shows mixed options pressure with a 39/100 conviction score, put-call volume ratio of 1.00, expected move of 34.0%, and Sharemaestro trend signal active.

Conviction39/100
Expected move34.0%
Put/call volume1.00
Pressure11
Speculation8
Volatility92
Trend agreement90
Open options detail
Insider activity14 / 6

14 acquisitions and 6 disposals in the latest 180-day insider tape.

Acquisitions / disposals over the latest 180 days. Insider activity is context, not a stand-alone signal.
News sentiment52/100

Weighted news tone is neutral across 60 relevant articles.

14 positive · 36 neutral · 10 negative
Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal
06 · Catalysts and risk

What can move the shares—and how volatile the path has been

Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.

Next earnings11dNext report is scheduled for 13 Aug 2026; event risk rises as the date approaches.
Options expected move34.0%Nearest-chain priced movement where available.
52-week drawdown-23.2%Distance below the 52-week high.
13-week volatility9.5%Standard deviation of weekly returns.

Weekly gains and losses

Latest 26 completed weeks

Each bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.

Weeks higher14 of 2611 weeks finished lower.
Best week+20.5%Week of 3 Apr.
Worst week-15.5%Week of 5 Jun.
Latest week+0.2%Week of 31 Jul.

Shape of recent returns

Strong gains10
Modest gains4
Flat weeks1
Modest losses5
Sharp losses6
Recent vol9.5%13-week weekly-return volatility.
Base vol7.5%52-week weekly-return volatility.
Up/down split26/25Count of positive and negative weeks in the 52-week window.
Average skew7.0% / -5.0%Average positive week versus average negative week.
07 · Sector and peer context

Is this stock leading—or simply moving with its group?

Sector and industry breadth distinguish company-specific strength from a broad group move.

08 · Evidence and weekly data

The underlying research record

Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.

Weekly tape55/100

Trend, activity pressure, participation, and risk combine to a 55/100 tape read.

 Indicator analysis78/100

Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 9/12.

Activity pressure 0.84; 3 reversal markers Next-Week ExpectancyNegative 40.97%

Next-week expectancy is negative with a 40.97% historical one-week setup read.

Adds short-term historical context without overriding trend, activity, or relative leadership. Factors49/100

O'Shaughnessy factor stack blends value, quality, momentum, and confidence.

Buyback Yield rank 79; Small Cap Core rank 54 Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal Options58/100

MGTX shows mixed options pressure with a 39/100 conviction score, put-call volume ratio of 1.00, expected move of 34.0%, and Sharemaestro trend signal active.

Mixed · Options-market disagreement · Expected move 34.0% Sentiment52/100

Weighted news tone is neutral across 60 relevant articles.

MGTX|MeiraGTx Holdings PLC|Price:11.810|Chg%:-0.490 Insiders14 / 6

14 acquisitions and 6 disposals in the latest 180-day insider tape.

 Earnings11d

Next report is scheduled for 13 Aug 2026; event risk rises as the date approaches.
WeekCloseReturnTrend LineFair ValuePressureLeadershipVolumeTrend
31 Jul 202611.79 USD0.2%9.37 USD6.77 USD0.7923.372.5MOn
24 Jul 202611.77 USD-5.4%9.23 USD6.73 USD1.0124.402.1MOn
17 Jul 202612.44 USD-7.1%9.11 USD6.69 USD1.3029.814.7MOn
10 Jul 202613.39 USD-3.8%8.96 USD6.66 USD1.3234.375.4MOn
3 Jul 202613.92 USD14.9%8.81 USD6.62 USD1.1242.855.1MOn
26 Jun 202612.11 USD7.0%8.64 USD6.57 USD0.8426.419.3MOn
19 Jun 202611.32 USD18.0%8.51 USD6.54 USD0.7413.664.7MOn
12 Jun 20269.59 USD6.6%8.38 USD6.51 USD0.68-0.692.9MOn
5 Jun 20269.00 USD-15.5%8.33 USD6.50 USD0.78-4.553.3MOn
29 May 202610.65 USD15.3%8.32 USD6.49 USD0.958.084.3MOn
22 May 20269.24 USD-1.7%8.26 USD6.47 USD0.90-2.885.2MOn
15 May 20269.40 USD-4.3%8.25 USD6.45 USD1.000.413.1MOn
8 May 20269.82 USD4.4%8.19 USD6.44 USD1.165.122.3MOn
1 May 20269.41 USD2.0%8.12 USD6.41 USD1.246.683.2MOn
How to use this report

This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.