LXRX NASDAQ Week ended 31 Jul 2026

Weekly Investor Report

Lexicon Pharmaceuticals Inc · Healthcare · Biotechnology

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Latest close 2.31 USD
0.9% latest week
Weekly setup

Mixed setup

The weekly trend is active. Price is 27.2% above the Trend Line and sits at 77.7% of its 52-week range. The latest completed week returned 0.9%, after a -0.4% four-week move. The latest factor snapshot indicates quality ranks weakly versus its universe; growth ranks strongly; valuation is expensive relative to peers. Options positioning is volatility with 53/100 conviction, while the latest news-sentiment score is 56/100. Near-term considerations: volume confirmation is below normal; earnings are due in 3d.

Setup score 64 out of 100
Latest Close 2.31 USD 31 Jul 2026
1W Return 0.9% latest completed week
4W Return -0.4% short-term follow-through
12W Return 15.5% quarterly tape
Trend Breadth 98.1% 51 of 52 weeks active
Volume Ratio 0.8x vs 13-week average
What is working
  • The trend backdrop is active with a 29-week active streak.
  • Price is above the Trend Line, keeping the weekly tape constructive.
  • Price is above Fair Value, showing premium demand versus the model.
  • Activity pressure is positive on the latest completed week.
What could go wrong
  • No major top-level risk cluster is currently dominant.
What to watch next
  • Trend Line remains the key weekly regime level.
  • Activity pressure is the gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through 0.9% Latest completed week; four-week move -0.4%. Indicator stack 99/63 Trend and activity pressure are weighted against the latest 12-week confirmation window. Trend backdrop Active The trend backdrop defines the current weekly regime. Patient Capital Quiet Activity-pressure buy-signal status for institutional accumulation timing. Options pressure Volatility 53/100 conviction; expected move 26.2%. News sentiment 56/100 62 relevant articles in the latest sentiment read. Event risk 3d Next report is scheduled for 05 Aug 2026; event risk rises as the date approaches.
01 · Price action

Where price is—and whether the trend supports it

The weekly trend is active. Price is 27.2% above the Trend Line and sits at 77.7% of its 52-week range. The latest completed week returned 0.9%, after a -0.4% four-week move.

Study the full chart

52-week price path

Price vs Trend Line and Fair Value
Price Trend Line Fair Value
02 · Volume and demand

Is real participation confirming the move?

Latest weekly volume is 0.8x the 13-week average. Participation is below its recent norm, so price strength is not receiving full volume confirmation.

26-week volume confirmation

Bar height shows volume; colour shows the weekly price direction
6 Feb 13 Feb 20 Feb 27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 3 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun 19 Jun 26 Jun 3 Jul 10 Jul 17 Jul 24 Jul 31 Jul
Up week Down week
Demand beneath price

Activity pressure and institutional-style signals

These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.

Activity pressure path

Latest 0.9812-week average 0.92

12-week confirmation

Trend active12/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure12/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership12/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.98Current proprietary activity-pressure read.
Buy signals0Accumulation signal count in the latest 12 weeks.
Reversal markers0No reversal markers

No recent accumulation markers. No reversal markers.

03 · Momentum and leadership

Is performance persistent—and is the stock leading?

Performance is -0.4% over four weeks, 15.5% over 12 weeks, and 115.9% over one year. The current trend has remained active for 29 consecutive weeks.

Performance by holding period

1W0.9%
4W-0.4%
12W15.5%
26W99.1%
52W115.9%
Active trend streak29 weeks
Active weeks in one year51
Trend breadth98.1%

Activity pressure vs relative leadership

Activity pressureRelative leadership
Pressure0.78Latest activity-pressure read.
Pressure change-18.4%Four-week change in activity pressure.
Leadership34.59Latest relative-leadership reading.
RS change-3.7%Four-week change in relative leadership.
04 · Fundamentals and valuation

What investors are paying for—and the quality behind it

The latest factor snapshot indicates quality ranks weakly versus its universe; growth ranks strongly; valuation is expensive relative to peers.

Open full factor analysis
Factor week 26 Jul 2026 Financial statements through 31 Mar 2026 Field coverage 82% Model confidence 78%

Relative factor standing

Higher display scores are better. Each score is converted from the underlying universe rank, where rank 1 is best.

Overall factor strength19/100Blend of value, momentum, and quality. Underlying universe rank 82; rank 1 is best.
Value18/100Relative valuation strength. Underlying universe rank 83; rank 1 is best.
Quality8/100Profitability and accounting quality. Underlying universe rank 93; rank 1 is best.
Momentum96/100Medium-term price momentum. Underlying universe rank 5; rank 1 is best.
Growth89/100Revenue and earnings growth. Underlying universe rank 12; rank 1 is best.
How to read this

Quality and valuation are separate questions

A strong company can still carry a demanding valuation. This report shows profitability, growth, balance-sheet strength, and the price paid for those characteristics separately.

Valuation

How much investors are paying for earnings, sales, and cash flow.

P/E
-
Price divided by trailing earnings.
Price / sales
14.6x
Market value relative to trailing revenue.
EV / EBITDA
-
Enterprise value relative to operating cash earnings.
Free-cash-flow yield
-3.7%
Free cash flow as a share of enterprise value.

Business quality

Margins and the return generated on invested capital.

Gross margin
99.1%
Gross profit retained from each unit of revenue.
Operating margin
-25.8%
Operating profit retained from revenue.
Free-cash-flow margin
-55.7%
Free cash flow generated from revenue.
Return on invested capital
-6.1%
Operating return generated on invested capital.

Growth and financial strength

Recent business growth and accounting strength.

Revenue growth
123.1%
Latest one-year revenue growth.
EPS growth
-
Latest one-year earnings-per-share growth.
Free-cash-flow growth
-
Latest one-year free-cash-flow growth.
Piotroski F-score
4/9
Nine-point accounting-strength checklist.

Shareholder return and balance sheet

Cash returned to owners and financial leverage.

Dividend yield
-
Cash dividends relative to market value.
Buyback yield
-9.4%
Net share repurchases relative to market value.
Shareholder yield
-9.4%
Dividend yield plus net buyback yield.
Net debt / EBITDA
-1.1x
Balance-sheet debt relative to operating cash earnings.
05 · Ownership, options, and sentiment

What other market participants are doing

Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.

Options positioningVolatility

LXRX shows volatility options pressure with a 53/100 conviction score, put-call volume ratio of 0.04, expected move of 26.2%, and Sharemaestro trend signal active.

Conviction53/100
Expected move26.2%
Put/call volume0.04
Pressure100
Speculation1
Volatility96
Trend agreement6
Open options detail
Insider activity13 / 7

13 acquisitions and 7 disposals in the latest 180-day insider tape.

Acquisitions / disposals over the latest 180 days. Insider activity is context, not a stand-alone signal.
News sentiment56/100

Weighted news tone is neutral across 62 relevant articles.

20 positive · 38 neutral · 4 negative
Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal
06 · Catalysts and risk

What can move the shares—and how volatile the path has been

Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.

Next earnings3dNext report is scheduled for 05 Aug 2026; event risk rises as the date approaches.
Options expected move26.2%Nearest-chain priced movement where available.
52-week drawdown-13.8%Distance below the 52-week high.
13-week volatility11.1%Standard deviation of weekly returns.

Weekly gains and losses

Latest 26 completed weeks

Each bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.

Weeks higher15 of 2610 weeks finished lower.
Best week+26.9%Week of 26 Jun.
Worst week-12.4%Week of 5 Jun.
Latest week+0.9%Week of 31 Jul.

Shape of recent returns

Strong gains12
Modest gains3
Flat weeks1
Modest losses4
Sharp losses6
Recent vol11.1%13-week weekly-return volatility.
Base vol10.6%52-week weekly-return volatility.
Up/down split28/22Count of positive and negative weeks in the 52-week window.
Average skew9.4% / -7.1%Average positive week versus average negative week.
07 · Sector and peer context

Is this stock leading—or simply moving with its group?

Sector and industry breadth distinguish company-specific strength from a broad group move.

08 · Evidence and weekly data

The underlying research record

Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.

Weekly tape68/100

Trend, activity pressure, participation, and risk combine to a 68/100 tape read.

 Indicator analysis91/100

Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 12/12.

Activity pressure 0.98; No reversal markers Factors32/100

O'Shaughnessy factor stack blends value, quality, momentum, and confidence.

Buyback Yield rank 86; Small Cap Core rank 88 Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal Options38/100

LXRX shows volatility options pressure with a 53/100 conviction score, put-call volume ratio of 0.04, expected move of 26.2%, and Sharemaestro trend signal active.

Volatility · Volatility expansion watch · Expected move 26.2% Sentiment56/100

Weighted news tone is neutral across 62 relevant articles.

Lexicon schedules Aug. 6 call and webcast for Q2 results Insiders13 / 7

13 acquisitions and 7 disposals in the latest 180-day insider tape.

 Earnings3d

Next report is scheduled for 05 Aug 2026; event risk rises as the date approaches.
WeekCloseReturnTrend LineFair ValuePressureLeadershipVolumeTrend
31 Jul 20262.31 USD0.9%1.82 USD1.43 USD0.7834.5913.3MOn
24 Jul 20262.29 USD-4.2%1.78 USD1.42 USD0.9635.6413.4MOn
17 Jul 20262.39 USD7.7%1.74 USD1.42 USD1.2540.8312.8MOn
10 Jul 20262.22 USD-4.3%1.70 USD1.42 USD1.1026.6114.8MOn
3 Jul 20262.32 USD-9.0%1.67 USD1.42 USD0.9635.9014.9MOn
26 Jun 20262.55 USD26.9%1.64 USD1.42 USD0.8352.6651.5MOn
19 Jun 20262.01 USD4.7%1.60 USD1.42 USD0.7516.9210.5MOn
12 Jun 20261.92 USD0.5%1.58 USD1.42 USD1.0015.909.1MOn
5 Jun 20261.91 USD-12.4%1.57 USD1.42 USD1.3619.3411.2MOn
29 May 20262.18 USD0.9%1.54 USD1.43 USD1.5931.488.5MOn
22 May 20262.16 USD-3.1%1.52 USD1.43 USD1.2236.078.9MOn
15 May 20262.23 USD11.5%1.49 USD1.44 USD0.9344.3428.2MOn
8 May 20262.00 USD22.7%1.47 USD1.44 USD0.7231.4816.9MOn
1 May 20261.63 USD-3.0%1.45 USD1.45 USD0.5114.467.1MOn
How to use this report

This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.