NASDAQ Equity Snapshot

SEPN Weekly Equity Report

Septerna, Inc. Common Stock

Interactive chart JSON snapshot
Latest Close 35.95 USD 12 Jun 2026
1W Return 15.4% latest completed week
4W Return 33.4% short-term follow-through
12W Return 48.7% quarterly tape
Trend Breadth 71.2% 37 of 52 weeks active
Volume Ratio 1.2x vs 13-week average
Company Brief

What the company does

Septerna, Inc. is a pioneering biotechnology firm dedicated to advancing transformative therapeutics through selective protein modulation. The company harnesses proprietary technologies and unparalleled scientific expertise to develop a promising pipeline of next-generation drug candidates aimed at addressing unmet medical needs across various disease areas. With a strong emphasis on research and development, Septerna is strategically positioned for growth, presenting a compelling investment opportunity for institutional investors in the rapidly evolving biopharmaceutical landscape.

Snapshot

What the weekly tape is saying

SEPN closed the latest completed week at 35.95 USD. The 4-week return is 33.4% and the 12-week return is 48.7%. Trend Signal is active, Market Dynamics is 0.70. Setup signature: Leadership continuation with a 75/100 composite read.

Trend Signal Active
Market Dynamics No fresh buy
Price vs Trend 34.2%
Volume 1.2x
Setup Cockpit

A compressed read of the whole setup

The radar blends trend persistence, momentum, Market Dynamics, Relative Strength, volume confirmation, and risk control into one weekly cockpit.

Composite setup radar

Scoreboard

Trend 50 Persistence of active Trend Signal over the last year and current streak.
Momentum 100 Blend of 4-week and 12-week follow-through.
Dynamics 85 Latest Market Dynamics and whether pressure has improved over four weeks.
Relative Strength 100 Relative leadership and short-term RS change.
Volume 48 Participation compared with the 13-week volume baseline.
Risk Control 69 Drawdown and recent weekly volatility pressure.

16-week signal tape

27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 2 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun
Weekly return bar Trend Signal dot Positive Market Dynamics dot
Price Action

Price, Trend Line, and Fair Value

Weekly price context with the latest close, trend position, Fair Value gap, drawdown, and 52-week range location.

52-week price path

Price Trend Line Fair Value

Price map

Trend Line
26.79 USD
Vs Trend Line
34.2%
Fair Value
18.88 USD
Vs Fair Value
90.5%
52W High
36.26 USD
52W Low
9.85 USD
Drawdown
-0.9%
Range Position
98.8%
Momentum

Returns and trend persistence

Return windows separate the latest week from short-term and medium-term follow-through.

Return windows

1W 15.4%
4W 33.4%
12W 48.7%
26W 41.3%
52W 253.5%

Trend read

Active Streak
3 weeks
52W Active Weeks
37
52W Active Breadth
71.2%
Sector Scope
US Healthcare
Sector Rank
51 of 1034
Sector Percentile
95.2%
Peer Context

Sector and industry pulse

Peer breadth helps separate a stock-specific move from a broader group rotation.

Market Dynamics

Pressure, Relative Strength, and expectation

Market Dynamics and Relative Strength show whether buying pressure and relative leadership are confirming the price move.

Dynamics path

Market Dynamics Relative Strength

Signal state

Market Dynamics
0.70
4W MD Change
277.8%
Relative Strength
39.67
4W RS Change
215.2%
Expectation
Undecided
Probability
49.85%
Volume

Participation and confirmation

Volume tells us whether the latest weekly move is being confirmed by unusual participation.

52-week volume profile

Volume map

Latest Volume
1.8M
13W Average
1.5M
52W Average
1.5M
Vs 13W
1.2x
Vs 52W
1.2x
Risk Anatomy

Volatility, downside weeks, and return shape

A compact risk profile shows whether the move is steady, volatile, or being driven by sharp one-week jumps.

26-week return distribution

Risk map

13W Volatility
7.3%
52W Volatility
8.7%
Upside Weeks
30
Downside Weeks
22
Downside Breadth
42.3%
Avg Gain / Loss
8.7% / -5.2%
Context

Classification, opportunities, risks, and watch points

Top-level read across company classification, constructive evidence, caution points, and the next things that matter.

Classification

Exchange
NASDAQ
Country
US
Sector
Healthcare
Industry
Biotechnology
Currency
USD
Market Cap
1.4B

Opportunity signals

  • Trend Signal is active with a 3-week active streak.
  • Price is above the Trend Line, keeping the weekly tape constructive.
  • Price is above Fair Value, showing premium demand versus the model.
  • Market Dynamics is positive on the latest completed week.

Risk signals

  • No major top-level risk cluster is currently dominant.

Watch next

  • Price is close to its 52-week high; watch for continuation or exhaustion.
  • Trend Line remains the key weekly regime level.
  • Market Dynamics is the pressure gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Weekly Tape

Recent completed weeks

The latest weekly rows behind the report snapshot.

Week Close Return Trend Fair Value MD RS Volume Signal
12 Jun 2026 35.95 USD 15.4% 26.79 USD 18.88 USD 0.70 39.67 1.8M On
5 Jun 2026 31.15 USD 3.1% 26.37 USD 18.67 USD 0.35 25.89 1.8M On
29 May 2026 30.20 USD 6.5% 25.95 USD 18.52 USD -0.01 18.16 1.0M On
22 May 2026 28.36 USD 5.2% 25.63 USD 18.38 USD -0.27 15.65 1.5M Off
15 May 2026 26.95 USD 12.9% 25.41 USD 18.26 USD -0.39 12.59 2.0M Off
8 May 2026 23.87 USD 1.1% 25.24 USD 18.15 USD -0.44 0.49 1.4M Off
1 May 2026 23.61 USD -4.3% 25.22 USD 18.07 USD -0.55 6.07 1.5M Off
24 Apr 2026 24.67 USD -5.6% 25.12 USD 18.00 USD -0.63 13.85 2.2M Off
17 Apr 2026 26.13 USD 13.2% 24.88 USD 17.92 USD -0.76 25.11 2.0M Off
10 Apr 2026 23.09 USD -8.3% 24.53 USD 17.81 USD -0.94 19.30 1.3M Off
2 Apr 2026 25.18 USD 5.5% 24.24 USD 17.74 USD -0.90 38.01 979.6K On
27 Mar 2026 23.87 USD -1.3% 23.88 USD 17.64 USD -0.74 38.61 971.0K On
20 Mar 2026 24.18 USD -3.8% 23.49 USD 17.55 USD -0.51 38.43 1.6M On
13 Mar 2026 25.14 USD -12.6% 23.08 USD 17.46 USD -0.40 43.79 1.6M On