OPK NASDAQ Week ended 31 Jul 2026

Weekly Investor Report

Opko Health Inc · Healthcare · Diagnostics & Research

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Latest close 1.32 USD
8.2% latest week
Weekly setup

Mixed setup

The weekly trend is active. Price is 4.3% above the Trend Line and sits at 45.6% of its 52-week range. The latest completed week returned 8.2%, after a -13.2% four-week move. The latest factor snapshot indicates quality ranks weakly versus its universe; growth ranks weakly; valuation is neither clearly cheap nor expensive. Options positioning is mixed with 38/100 conviction, while the latest news-sentiment score is 53/100.

Setup score 40 out of 100
Latest Close 1.32 USD 31 Jul 2026
1W Return 8.2% latest completed week
4W Return -13.2% short-term follow-through
12W Return 15.8% quarterly tape
Trend Breadth 19.2% 10 of 52 weeks active
Volume Ratio 3.3x vs 13-week average
What is working
  • The trend backdrop is active with a 6-week active streak.
  • Price is above the Trend Line, keeping the weekly tape constructive.
  • Activity pressure is positive on the latest completed week.
  • Volume is elevated versus the 13-week average, confirming attention.
What could go wrong
  • Price is below Fair Value, so the market is still discounting the latest tape.
  • The share remains more than 20% below its 52-week high.
  • Recent volatility is running well above the one-year baseline.
What to watch next
  • Trend Line remains the key weekly regime level.
  • Activity pressure is the gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through 8.2% Latest completed week; four-week move -13.2%. Indicator stack 31/49 Trend and activity pressure are weighted against the latest 12-week confirmation window. Trend backdrop Active The trend backdrop defines the current weekly regime. Patient Capital Quiet Activity-pressure buy-signal status for institutional accumulation timing. Options pressure Mixed 38/100 conviction; expected move 15.9%. News sentiment 53/100 53 relevant articles in the latest sentiment read. Event risk 30 Jul Latest stored earnings date was 30 Jul 2026.
01 · Price action

Where price is—and whether the trend supports it

The weekly trend is active. Price is 4.3% above the Trend Line and sits at 45.6% of its 52-week range. The latest completed week returned 8.2%, after a -13.2% four-week move.

Study the full chart

52-week price path

Price vs Trend Line and Fair Value
Price Trend Line Fair Value
02 · Volume and demand

Is real participation confirming the move?

Latest weekly volume is 3.3x the 13-week average. Participation is unusually strong and confirms that the move is attracting attention.

26-week volume confirmation

Bar height shows volume; colour shows the weekly price direction
6 Feb 13 Feb 20 Feb 27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 3 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun 19 Jun 26 Jun 3 Jul 10 Jul 17 Jul 24 Jul 31 Jul
Up week Down week
Demand beneath price

Activity pressure and institutional-style signals

These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.

Activity pressure path

Latest 0.6212-week average 0.33

12-week confirmation

Trend active6/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure10/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership1/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.62Current proprietary activity-pressure read.
Buy signals0Accumulation signal count in the latest 12 weeks.
Reversal markers0No reversal markers

No recent accumulation markers. No reversal markers.

03 · Momentum and leadership

Is performance persistent—and is the stock leading?

Performance is -13.2% over four weeks, 15.8% over 12 weeks, and 10.9% over one year. The current trend has remained active for 6 consecutive weeks.

Performance by holding period

1W8.2%
4W-13.2%
12W15.8%
26W4.8%
52W10.9%
Active trend streak6 weeks
Active weeks in one year10
Trend breadth19.2%

Activity pressure vs relative leadership

Activity pressureRelative leadership
Pressure0.31Latest activity-pressure read.
Pressure change-76.7%Four-week change in activity pressure.
Leadership-8.28Latest relative-leadership reading.
RS change-29033.9%Four-week change in relative leadership.
04 · Fundamentals and valuation

What investors are paying for—and the quality behind it

The latest factor snapshot indicates quality ranks weakly versus its universe; growth ranks weakly; valuation is neither clearly cheap nor expensive.

Open full factor analysis
Factor week 26 Jul 2026 Financial statements through 31 Mar 2026 Field coverage 82% Model confidence 78%

Relative factor standing

Higher display scores are better. Each score is converted from the underlying universe rank, where rank 1 is best.

Overall factor strength7/100Blend of value, momentum, and quality. Underlying universe rank 94; rank 1 is best.
Value31/100Relative valuation strength. Underlying universe rank 70; rank 1 is best.
Quality2/100Profitability and accounting quality. Underlying universe rank 99; rank 1 is best.
Momentum25/100Medium-term price momentum. Underlying universe rank 76; rank 1 is best.
Growth15/100Revenue and earnings growth. Underlying universe rank 86; rank 1 is best.
How to read this

Quality and valuation are separate questions

A strong company can still carry a demanding valuation. This report shows profitability, growth, balance-sheet strength, and the price paid for those characteristics separately.

Valuation

How much investors are paying for earnings, sales, and cash flow.

P/E
-
Price divided by trailing earnings.
Price / sales
1.6x
Market value relative to trailing revenue.
EV / EBITDA
-
Enterprise value relative to operating cash earnings.
Free-cash-flow yield
-15.6%
Free cash flow as a share of enterprise value.

Business quality

Margins and the return generated on invested capital.

Gross margin
22.7%
Gross profit retained from each unit of revenue.
Operating margin
-21.5%
Operating profit retained from revenue.
Free-cash-flow margin
-26.2%
Free cash flow generated from revenue.
Return on invested capital
-7.4%
Operating return generated on invested capital.

Growth and financial strength

Recent business growth and accounting strength.

Revenue growth
-15.7%
Latest one-year revenue growth.
EPS growth
-
Latest one-year earnings-per-share growth.
Free-cash-flow growth
-
Latest one-year free-cash-flow growth.
Piotroski F-score
3/9
Nine-point accounting-strength checklist.

Shareholder return and balance sheet

Cash returned to owners and financial leverage.

Dividend yield
-
Cash dividends relative to market value.
Buyback yield
5.6%
Net share repurchases relative to market value.
Shareholder yield
5.6%
Dividend yield plus net buyback yield.
Net debt / EBITDA
-1.6x
Balance-sheet debt relative to operating cash earnings.
05 · Ownership, options, and sentiment

What other market participants are doing

Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.

Options positioningMixed

OPK shows mixed options pressure with a 38/100 conviction score, put-call volume ratio of 1.41, expected move of 15.9%, and Sharemaestro trend signal active.

Conviction38/100
Expected move15.9%
Put/call volume1.41
Pressure-6
Speculation7
Volatility96
Trend agreement95
Open options detail
Insider activity6 / 0

6 acquisitions and 0 disposals in the latest 180-day insider tape.

Acquisitions / disposals over the latest 180 days. Insider activity is context, not a stand-alone signal.
News sentiment53/100

Weighted news tone is neutral across 53 relevant articles.

14 positive · 32 neutral · 7 negative
Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal
06 · Catalysts and risk

What can move the shares—and how volatile the path has been

Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.

Next earnings30 JulLatest stored earnings date was 30 Jul 2026.
Options expected move15.9%Nearest-chain priced movement where available.
52-week drawdown-23.7%Distance below the 52-week high.
13-week volatility8.1%Standard deviation of weekly returns.

Weekly gains and losses

Latest 26 completed weeks

Each bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.

Weeks higher10 of 2613 weeks finished lower.
Best week+15.5%Week of 22 May.
Worst week-11.9%Week of 17 Jul.
Latest week+8.2%Week of 31 Jul.

Shape of recent returns

Strong gains5
Modest gains5
Flat weeks3
Modest losses9
Sharp losses4
Recent vol8.1%13-week weekly-return volatility.
Base vol5.6%52-week weekly-return volatility.
Up/down split22/26Count of positive and negative weeks in the 52-week window.
Average skew5.3% / -3.8%Average positive week versus average negative week.
07 · Sector and peer context

Is this stock leading—or simply moving with its group?

Sector and industry breadth distinguish company-specific strength from a broad group move.

08 · Evidence and weekly data

The underlying research record

Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.

Weekly tape39/100

Trend, activity pressure, participation, and risk combine to a 39/100 tape read.

 Indicator analysis51/100

Latest 12-week confirmation: trend 6/12, activity pressure 10/12, relative leadership 1/12.

Activity pressure 0.62; No reversal markers Factors14/100

O'Shaughnessy factor stack blends value, quality, momentum, and confidence.

Buyback Yield rank 11; Small Cap Core rank 24 Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal Options59/100

OPK shows mixed options pressure with a 38/100 conviction score, put-call volume ratio of 1.41, expected move of 15.9%, and Sharemaestro trend signal active.

Mixed · Options-market disagreement · Expected move 15.9% Sentiment53/100

Weighted news tone is neutral across 53 relevant articles.

OPKO Health (OPK) Is Up 14.1% After Narrower Q2 Loss and New 2026 Revenue Guidance – Has The Bull Case Changed? Insiders6 / 0

6 acquisitions and 0 disposals in the latest 180-day insider tape.

 Earnings30 Jul

Latest stored earnings date was 30 Jul 2026.
WeekCloseReturnTrend LineFair ValuePressureLeadershipVolumeTrend
31 Jul 20261.32 USD8.2%1.26 USD1.38 USD0.31-8.2854.2MOn
24 Jul 20261.22 USD2.5%1.26 USD1.38 USD0.54-14.9514.0MOn
17 Jul 20261.19 USD-11.9%1.27 USD1.39 USD0.94-18.8515.5MOn
10 Jul 20261.35 USD-11.2%1.27 USD1.39 USD1.19-12.3311.1MOn
3 Jul 20261.52 USD-0.7%1.27 USD1.40 USD1.34-0.0313.2MOn
26 Jun 20261.53 USD7.7%1.26 USD1.40 USD1.391.2019.3MOn
19 Jun 20261.42 USD0.0%1.26 USD1.41 USD1.34-10.5011.9MOff
12 Jun 20261.42 USD-1.4%1.26 USD1.41 USD1.36-8.5510.0MOff
5 Jun 20261.44 USD-1.4%1.25 USD1.41 USD0.94-5.6018.1MOff
29 May 20261.46 USD15.0%1.25 USD1.41 USD0.47-9.0313.0MOff
22 May 20261.27 USD15.5%1.24 USD1.41 USD-0.06-19.0514.4MOff
15 May 20261.10 USD-3.5%1.25 USD1.41 USD-0.31-29.4710.0MOff
8 May 20261.14 USD3.6%1.27 USD1.41 USD-0.24-27.789.9MOff
1 May 20261.10 USD-10.6%1.28 USD1.42 USD-0.41-27.0817.6MOff
How to use this report

This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.