NASDAQ Equity Snapshot

SION Weekly Equity Report

Sionna Therapeutics, Inc. Common Stock

Interactive chart JSON snapshot
Latest Close 35.92 USD 12 Jun 2026
1W Return 1.6% latest completed week
4W Return -10.7% short-term follow-through
12W Return -1.3% quarterly tape
Trend Breadth 63.5% 33 of 52 weeks active
Volume Ratio 0.9x vs 13-week average
Company Brief

What the company does

Sionna Therapeutics, Inc. is at the forefront of biotechnology innovation, focusing on the development of advanced therapies for neurodegenerative disorders characterized by protein misfolding, notably Alzheimer's and Parkinson's diseases. Leveraging proprietary technologies and a strong pipeline, Sionna addresses crucial unmet medical needs within this therapeutic area. The company's strategic partnerships and robust commitment to research and development position it as a key player in the biopharmaceutical industry, dedicated to enhancing patient quality of life through transformative neurological advancements.

Snapshot

What the weekly tape is saying

SION closed the latest completed week at 35.92 USD. The 4-week return is -10.7% and the 12-week return is -1.3%. Trend Signal is inactive, Market Dynamics is -0.02. Setup signature: Risk-first tape with a 25/100 composite read.

Trend Signal Inactive
Market Dynamics No fresh buy
Price vs Trend -9.4%
Volume 0.9x
Setup Cockpit

A compressed read of the whole setup

The radar blends trend persistence, momentum, Market Dynamics, Relative Strength, volume confirmation, and risk control into one weekly cockpit.

Composite setup radar

Scoreboard

Trend 35 Persistence of active Trend Signal over the last year and current streak.
Momentum 24 Blend of 4-week and 12-week follow-through.
Dynamics 41 Latest Market Dynamics and whether pressure has improved over four weeks.
Relative Strength 9 Relative leadership and short-term RS change.
Volume 36 Participation compared with the 13-week volume baseline.
Risk Control 5 Drawdown and recent weekly volatility pressure.

16-week signal tape

27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 2 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun
Weekly return bar Trend Signal dot Positive Market Dynamics dot
Price Action

Price, Trend Line, and Fair Value

Weekly price context with the latest close, trend position, Fair Value gap, drawdown, and 52-week range location.

52-week price path

Price Trend Line Fair Value

Price map

Trend Line
39.63 USD
Vs Trend Line
-9.4%
Fair Value
28.44 USD
Vs Fair Value
26.3%
52W High
48.45 USD
52W Low
13.51 USD
Drawdown
-25.9%
Range Position
64.1%
Momentum

Returns and trend persistence

Return windows separate the latest week from short-term and medium-term follow-through.

Return windows

1W 1.6%
4W -10.7%
12W -1.3%
26W -16.0%
52W 119.3%

Trend read

Active Streak
0 weeks
52W Active Weeks
33
52W Active Breadth
63.5%
Sector Scope
US Healthcare
Sector Rank
436 of 1038
Sector Percentile
58.1%
Peer Context

Sector and industry pulse

Peer breadth helps separate a stock-specific move from a broader group rotation.

Market Dynamics

Pressure, Relative Strength, and expectation

Market Dynamics and Relative Strength show whether buying pressure and relative leadership are confirming the price move.

Dynamics path

Market Dynamics Relative Strength

Signal state

Market Dynamics
-0.02
4W MD Change
-113.2%
Relative Strength
-8.36
4W RS Change
-201.5%
Expectation
Undecided
Probability
47.11%
Volume

Participation and confirmation

Volume tells us whether the latest weekly move is being confirmed by unusual participation.

52-week volume profile

Volume map

Latest Volume
1.6M
13W Average
1.9M
52W Average
1.5M
Vs 13W
0.9x
Vs 52W
1.1x
Risk Anatomy

Volatility, downside weeks, and return shape

A compact risk profile shows whether the move is steady, volatile, or being driven by sharp one-week jumps.

26-week return distribution

Risk map

13W Volatility
9.4%
52W Volatility
10.6%
Upside Weeks
28
Downside Weeks
24
Downside Breadth
46.2%
Avg Gain / Loss
9.4% / -6.5%
Context

Classification, opportunities, risks, and watch points

Top-level read across company classification, constructive evidence, caution points, and the next things that matter.

Classification

Exchange
NASDAQ
Country
US
Sector
Healthcare
Industry
Biotechnology
Currency
USD
Market Cap
1.9B

Opportunity signals

  • Price is above Fair Value, showing premium demand versus the model.

Risk signals

  • Trend Signal is inactive, so price action has not confirmed a constructive regime.
  • Price is below the Trend Line, which keeps downside pressure in focus.
  • Market Dynamics is negative, which weakens the current setup.
  • The share remains more than 20% below its 52-week high.

Watch next

  • Trend Line remains the key weekly regime level.
  • Market Dynamics is the pressure gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Weekly Tape

Recent completed weeks

The latest weekly rows behind the report snapshot.

Week Close Return Trend Fair Value MD RS Volume Signal
12 Jun 2026 35.92 USD 1.6% 39.63 USD 28.44 USD -0.02 -8.36 1.6M Off
5 Jun 2026 35.37 USD -17.4% 39.67 USD 28.33 USD 0.22 -7.07 2.1M Off
29 May 2026 42.82 USD 4.1% 39.64 USD 28.23 USD 0.42 8.12 1.4M Off
22 May 2026 41.13 USD 2.3% 39.49 USD 28.01 USD 0.27 8.08 1.5M Off
15 May 2026 40.22 USD -9.1% 39.43 USD 27.81 USD 0.19 8.23 2.3M Off
8 May 2026 44.23 USD 13.0% 39.15 USD 27.62 USD 0.23 20.00 2.2M Off
1 May 2026 39.15 USD 2.7% 38.66 USD 27.36 USD -0.04 13.61 1.8M Off
24 Apr 2026 38.11 USD -12.5% 38.35 USD 27.18 USD -0.02 13.59 2.1M On
17 Apr 2026 43.54 USD 14.9% 38.05 USD 27.00 USD -0.17 34.40 3.4M On
10 Apr 2026 37.89 USD -6.4% 37.37 USD 26.73 USD -0.55 26.23 1.4M Off
2 Apr 2026 40.49 USD 12.0% 36.86 USD 26.54 USD -0.65 43.42 2.0M On
27 Mar 2026 36.16 USD -0.6% 36.31 USD 26.31 USD -0.81 35.64 1.7M On
20 Mar 2026 36.39 USD -2.5% 35.93 USD 26.14 USD -0.87 34.25 1.5M On
13 Mar 2026 37.32 USD 3.9% 35.53 USD 25.96 USD -0.90 36.89 1.3M On