Sharemaestro company-news research for Sionna Therapeutics, Inc. Common Stock (SION), showing current tone, evidence confidence, direct company coverage, sector and industry context, completed price response and the source headlines used on the page. Scores describe published news evidence. Confidence describes the amount, freshness, source breadth and direct company relevance of that evidence. Price context is shown separately.

NASDAQ United States Measured evidence

Company news sentiment

Latest SION news and sentiment

Sionna Therapeutics, Inc. Common Stock

Company headlines from the last 30 days, weighted by freshness, relevance, publisher quality and the strength of the wording. Price is shown separately.

30-day score36Neutral is 50
Cautious news tone 38/100 evidence confidence 100% direct company focus 58 current stories across 25 publishers
Latest weekly closeUSD 7.18week of 4 Sep 2026
Main news subjectEarnings74/100 share of current news
News data statusPartial63 duplicate stories removed

Current company news

Cautious news tone

The score uses 58 current company stories from 25 publishers.

Observed headline tone26/100 Published 30-day score36/100

Older, less relevant and less reliable stories count for less. Confidence is shown separately.

Latest source headline Sionna Therapeutics, Inc. (SION) Investigation: Bronstein, Gewirtz & Grossman, LLC Encourages Shareholders to Contact the Firm to Learn More About the Investigation The National Law Review ยท 26 Aug 2026 23:04

What supports the score

Direct evidence

58 current stories are mapped specifically to SION.

Source breadth

The score uses 25 publishers rather than depending on one outlet.

Story agreement

The current stories agree at 94/100.

Price response

Cautious headlines are being absorbed by price, which can signal underlying demand.

What limits the score

No major limit stands out.

36/100
News scoreCautious news tone
38/100
Confidencethin evidence
100%/100
Company news58 company stories
94/100
Story agreement6/100 difference

News history

Daily score and story count over 30 days

Daily weighted evidence
07 Aug: 1 stories08 Aug: 2 stories10 Aug: 18 stories11 Aug: 10 stories12 Aug: 4 stories13 Aug: 3 stories15 Aug: 1 stories16 Aug: 1 stories18 Aug: 1 stories19 Aug: 2 stories20 Aug: 2 stories21 Aug: 1 stories23 Aug: 1 stories24 Aug: 1 stories25 Aug: 4 stories26 Aug: 1 stories 07 Aug: tone 41, 1 stories08 Aug: tone 44, 2 stories10 Aug: tone 33, 18 stories11 Aug: tone 34, 10 stories12 Aug: tone 20, 4 stories13 Aug: tone 50, 3 stories15 Aug: tone 30, 1 stories16 Aug: tone 22, 1 stories18 Aug: tone 19, 1 stories19 Aug: tone 23, 2 stories20 Aug: tone 26, 2 stories21 Aug: tone 50, 1 stories23 Aug: tone 28, 1 stories24 Aug: tone 50, 1 stories25 Aug: tone 31, 4 stories26 Aug: tone 25, 1 stories 95505
07 Aug22 Aug05 Sep
News scoreStory count50 baseline

Confidence

How reliable the score is

Separate from direction

Confidence uses the amount of news, separate publishers, direct company relevance, freshness and agreement. A high or low score is not automatically reliable.

Amount of evidence23
1.155 after freshness weighting
Source breadth100
25 independent publishers
Company relevance100
share tied directly to this company
Freshness9
recency-weighted evidence
Agreement94
how closely stories agree
Publisher mix64
less reliance on one publisher

Price and news history

Weekly price and news-score history

Bad news being absorbed

Cautious headlines are being absorbed by price, which can signal underlying demand.

26 completed price weeks11 comparable news-score weeks
One scoring method across the chart.Stored company headlines are recalculated at each weekly point with the current 30-day freshness weighting. Old published snapshots are left unchanged.
13 Mar 2026: close 37.32, indexed 100.020 Mar 2026: close 36.39, indexed 97.527 Mar 2026: close 36.16, indexed 96.903 Apr 2026: close 40.49, indexed 108.510 Apr 2026: close 37.89, indexed 101.517 Apr 2026: close 43.54, indexed 116.724 Apr 2026: close 38.11, indexed 102.101 May 2026: close 39.15, indexed 104.908 May 2026: close 44.23, indexed 118.515 May 2026: close 40.22, indexed 107.822 May 2026: close 41.13, indexed 110.229 May 2026: close 42.82, indexed 114.705 Jun 2026: close 35.37, indexed 94.812 Jun 2026: close 35.92, indexed 96.219 Jun 2026: close 37.3, indexed 99.926 Jun 2026: close 42.18, indexed 113.003 Jul 2026: close 43.99, indexed 117.910 Jul 2026: close 45.29, indexed 121.417 Jul 2026: close 49.41, indexed 132.424 Jul 2026: close 45.7, indexed 122.531 Jul 2026: close 47.13, indexed 126.307 Aug 2026: close 51.04, indexed 136.814 Aug 2026: close 6.46, indexed 17.321 Aug 2026: close 5.29, indexed 14.228 Aug 2026: close 5.87, indexed 15.704 Sep 2026: close 7.18, indexed 19.2 26 Jun 2026: news score 50, close 42.18, 3 stories5003 Jul 2026: news score 50, close 43.99, 5 stories10 Jul 2026: news score 49, close 45.29, 9 stories4917 Jul 2026: news score 50, close 49.41, 15 stories24 Jul 2026: news score 49, close 45.7, 21 stories4931 Jul 2026: news score 49, close 47.13, 25 stories07 Aug 2026: news score 53, close 51.04, 35 stories5314 Aug 2026: news score 39, close 6.46, 72 stories21 Aug 2026: news score 33, close 5.29, 68 stories3328 Aug 2026: news score 34, close 5.87, 70 stories04 Sep 2026: news score 38, close 7.18, 62 stories38 Price index 151.5 75.5 -0.5 News score 100 50 0
13 Mar09 Jun04 Sep
Weekly close, indexedSentiment score
26-week price-80.8%latest close 7.18
News score change-12first to latest comparable week
One-week response+11.0%Price confirming higher
Fair-value position-79.9%Below fair value
WeekNews scoreCloseWeekly move
04 Sep 202638USD 7.18+22.3%
28 Aug 202634USD 5.87+11.0%
21 Aug 202633USD 5.29-18.1%
14 Aug 202639USD 6.46-87.3%
07 Aug 202653USD 51.04+8.3%
31 Jul 202649USD 47.13+3.1%
24 Jul 202649USD 45.7-7.5%
17 Jul 202650USD 49.41+9.1%
Caution agrees with inactive trend

News subjects

What is shaping the score

Earnings
Earnings3723 stories ยท 40%
Market update5012 stories ยท 21%
Regulatory and legal2511 stories ยท 19%
Analyst action4610 stories ยท 17%
Balance sheet312 stories ยท 3%

Source mix

Where the evidence comes from

64/100 independence
MarketBeat407 stories ยท 12%
Simply Wall St.504 stories ยท 7%
PR Newswire243 stories ยท 5%
GlobeNewswire293 stories ยท 5%
Stock Titan423 stories ยท 5%
TradingView503 stories ยท 5%
Business Wire222 stories ยท 3%

Recurring subjects

Subjects appearing most often

Current evidence
Life Sciences39Financial Markets28Earnings25Finance13IPO3Clinical Trials3CLINICAL-TRIALS3Biotech3BIOTECH3EARNINGS2

Earlier readings

How the score has changed

42 comparable readings ยท 76 days
Past and present use the same method.Each point recalculates the previous 30 days of stored company headlines with today's scoring rules. The original stored snapshots remain unchanged.
Comparable move-1250 to 38 ยท Weakening
Observed range33โ€“5450 is the neutral baseline
Evidence depth59stories at latest stored reading ยท +58
Confidence33/100Measured ยท +33
21 Jun50 neutral05 Sep 13:25
ConstructiveBalanced or withheldCautious

Changes in the stored score

Scores are rebuilt from stored headlines with the current 30-day method. Days with no change are collapsed.

ObservedScoreMoveConfidenceStoriesStatus
05 Sep 13:2538+533/100 (-22)59 (-12)Measured
26 Aug 23:5933-155/100 (0)71 (-1)Measured
25 Aug 23:5934+055/100 (+5)72 (+4)Measured
24 Aug 23:5934+050/100 (-3)68 (-1)Measured
23 Aug 23:5934+153/100 (-3)69 (+1)Measured
21 Aug 23:5933+056/100 (-4)68 (0)Measured
20 Aug 23:5933-160/100 (+4)68 (0)Measured
19 Aug 23:5934-256/100 (+4)68 (+1)Measured

Source headlines

The news behind the score

Showing 1-30 of 58

Only company-specific stories enter this score. The latest 30 days are shown newest first, with newer stories weighted more heavily and duplicate coverage combined.

#125Tone
The National Law ReviewDirect company coverageStored article

Sionna Therapeutics, Inc. (SION) Investigation: Bronstein, Gewirtz & Grossman, LLC Encourages Shareholders to Contact the Firm to Learn More About the Investigation

Bronstein, Gewirtz & Grossman, LLC has launched an investigation into Sionna Therapeutics, Inc. (NASDAQ: SION) following a significant drop in its stock price. This comes after Sionna reported disappointing topline data from its PreciSION CF Phase 2a trial and announced it would not advance SION-719. The firm is encouraging shareholders who purchased Sionna securities to contact them to learn more about potential claims.

FinanceIPOLife Sciences
Published
26 Aug 2026 23:04
News subject
Regulatory and legal
Why this score
Legal or regulatory risk
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 61/100
30-day weight
12.8% of the score ยท 8.4d old
Duplicates
1 consolidated
#231Tone
GlobeNewswireDirect company coverageStored article

Robbins LLP Reminds Investors it is Investigating Sionna Therapeutics for Potential Securities Violations

Robbins LLP is investigating Sionna Therapeutics (NASDAQ: SION) for potential securities violations and breaches of fiduciary duties after its stock plunged 92% following disappointing Phase 2a clinical trial results for SION-719 in cystic fibrosis. The trial failed to meet its primary endpoint, leading the company to consider capital preservation measures. Shareholders who lost money are encouraged to contact Robbins LLP for more information.

Financial MarketsLife Sciences
Published
25 Aug 2026 20:12
News subject
Earnings
Why this score
Large negative market reaction, Failed To Meet, Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 51/100
30-day weight
6.5% of the score ยท 9.5d old
Duplicates
1 consolidated
#327Tone
GlobeNewswireDirect company coverageStored article

Securities Fraud Investigation Into Sionna Therapeutics,

The Law Offices of Frank R. Cruz is continuing its investigation into Sionna Therapeutics, Inc. (SION) regarding potential violations of federal securities laws after the company announced a primary endpoint miss in its PreciSION CF Phase 2a trial. This news led to a 91.2% stock drop, injuring investors. Shareholders who lost money are encouraged to contact the firm to potentially pursue a claim.

EarningsLife Sciences
Published
25 Aug 2026 19:12
News subject
Regulatory and legal
Why this score
Legal or regulatory risk, Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 58/100
30-day weight
11.7% of the score ยท 9.6d old
Duplicates
1 consolidated
#4Not directional
TradingViewDirect company coverageScored from headline

Net income before discontinued operations of Sionna Therapeutics, Inc. โ€“ BMV:SION

Published
25 Aug 2026 17:26
News subject
Market update
Why this score
The headline reports news without a clear direction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 9.7d old
Duplicates
1 consolidated
#5Not directional
TradingViewDirect company coverageStored article

SION Forecast โ€” Price Target โ€” Prediction for 2027

This article provides a forecast and price target for Sionna Therapeutics, Inc. (SION), based on analyst opinions. It details maximum and minimum price estimates, upcoming earnings reports, historical financial data such as EPS, revenue, and net income, and confirms that SION does not pay dividends.

EarningsFinancial MarketsLife Sciences
Published
25 Aug 2026 17:12
News subject
Earnings
Why this score
The headline reports news without a clear direction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 9.7d old
Duplicates
1 consolidated
#6Not directional
MoomooDirect company coverageStored article

Raymond James Initiates Sionna Therapeutics(SION.US) With Hold Rating

Raymond James has initiated coverage on Sionna Therapeutics (SION.US) with a Hold rating. This indicates a neutral stance on the stock by the brokerage firm.

FinanceLife Sciences
Published
24 Aug 2026 09:49
News subject
Analyst action
Why this score
The headline reports news without a clear direction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 11.0d old
Duplicates
1 consolidated
#728Tone
ACCESS NewswireDirect company coverageStored article

Bronstein, Gewirtz & Grossman, LLC Initiates an Investigation into Allegations Against Sionna Therapeutics, Inc. (SION) And Encourages Stockholders to Reach Out

Bronstein, Gewirtz & Grossman, LLC has launched an investigation into Sionna Therapeutics, Inc. (SION) following a significant drop in its stock price. This comes after Sionna reported a primary endpoint miss in its PreciSION CF Phase 2a trial and announced it would not advance SION-719. The law firm is encouraging investors who purchased Sionna securities to contact them to assist with the investigation into potential claims.

Financial MarketsIPOLife Sciences
Published
23 Aug 2026 22:12
News subject
Regulatory and legal
Why this score
Legal or regulatory risk
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 55/100
30-day weight
8.8% of the score ยท 11.5d old
Duplicates
1 consolidated
#922Tone
Business WireDirect company coverageStored article

Investigation Launched into Sionna Therapeutics, Inc. (SION), Robbins Geller Rudman & Dowd LLP Attorneys Encourage Investors and Potential Witnesses to Contact Law Firm

Robbins Geller Rudman & Dowd LLP has launched an investigation into potential violations of U.S. federal securities laws by Sionna Therapeutics, Inc. (NASDAQ: SION). This follows an announcement by Sionna Therapeutics on August 10, 2026, that its SION-719 Phase 2a trial did not meet its key activity endpoint, causing a stock price drop of over 91%. The law firm is encouraging investors who suffered losses and potential witnesses to contact them for more information.

FinanceFinancial MarketsLife Sciences
Published
20 Aug 2026 06:12
News subject
Regulatory and legal
Why this score
Legal or regulatory risk, Large negative market reaction, Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 60/100
30-day weight
8.8% of the score ยท 15.1d old
Duplicates
1 consolidated
#1030Tone
PR NewswireDirect company coverageStored article

Robbins LLP Reminds Stockholders it is Investigating the Recent Stock Drop of Sionna Therapeutics

Robbins LLP, a shareholder rights law firm, is investigating Sionna Therapeutics (NASDAQ: SION) following a 92% stock drop. The investigation comes after the company reported disappointing results from its Phase 2a study of SION-719 for cystic fibrosis, failing to meet its key activity endpoint. Shareholders who have lost money investing in Sionna Therapeutics are encouraged to contact Robbins LLP for more information.

EarningsFinanceFinancial MarketsLife Sciences
Published
20 Aug 2026 02:41
News subject
Regulatory and legal
Why this score
Negative market reaction, Legal or regulatory risk
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 52/100
30-day weight
7.4% of the score ยท 15.3d old
Duplicates
1 consolidated
#1123Tone
PR NewswireDirect company coverageStored article

Sionna Therapeutics (SION) Securities Investigation Notice - Levi & Korsinsky

Levi & Korsinsky, LLP has announced a securities investigation into Sionna Therapeutics (NASDAQ: SION) following a significant 92% drop in its share price. This decline occurred after the company revealed that its Phase 2a PreciSION CF trial for SION-719 failed to meet its primary endpoint, leading to the decision not to advance the candidate as an add-on therapy. The investigation will examine whether investors received adequate disclosure regarding the company's reliance on its NBD1 stabilizer programs and the associated risks.

FinanceLife Sciences
Published
19 Aug 2026 17:10
News subject
Regulatory and legal
Why this score
Legal or regulatory risk, Failed To Meet
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 59/100
30-day weight
8.3% of the score ยท 15.7d old
Duplicates
2 consolidated
#1223Tone
ACCESS NewswireDirect company coverageStored article

Bronstein, Gewirtz & Grossman, LLC Announces an Investigation Against Sionna Therapeutics, Inc. (SION) and Encourages Stockholders to Learn More About the Investigation

Bronstein, Gewirtz & Grossman, LLC has launched an investigation into Sionna Therapeutics, Inc. (SION) following a significant drop in its stock price. The investigation stems from Sionna's August 10, 2026, announcement of topline data from its PreciSION CF Phase 2a trial, which included a primary endpoint miss and the decision not to advance SION-719 as an add-on therapy. The firm encourages Sionna stockholders to join the investigation, which aims to recover investor capital.

Financial MarketsIPOLife Sciences
Published
19 Aug 2026 13:00
News subject
Regulatory and legal
Why this score
Legal or regulatory risk
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 58/100
30-day weight
6.7% of the score ยท 15.8d old
Duplicates
1 consolidated
#1319Tone
WBOC TVDirect company coverageStored article

Securities Fraud Investigation Into Sionna Therapeutics, Inc. (SION) Announced โ€“ Shareholders Who Lost Money Urged To Contact Glancy Prongay Wolke & Rotter LLP, a Leading Securities Fraud Law Firm

Glancy Prongay Wolke & Rotter LLP has initiated a securities fraud investigation into Sionna Therapeutics, Inc. (SION) following a significant stock drop. The investigation comes after Sionna announced a primary endpoint miss in its PreciSION CF Phase 2a trial and decided not to advance SION-719, causing its stock to fall over 91%. Shareholders who suffered losses are encouraged to contact the firm to learn about potentially recovering their investments.

EarningsFinanceFinancial MarketsLife Sciences
Published
18 Aug 2026 14:42
News subject
Regulatory and legal
Why this score
Legal or regulatory risk, Large negative market reaction, Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 62/100
30-day weight
7.3% of the score ยท 16.8d old
Duplicates
2 consolidated
#1422Tone
Business WireDirect company coverageStored article

SION Investors Have Opportunity to Join Sionna Therapeutics, Inc. Fraud Investigation with SBS Law

Schall, Brown & Schwartz LLP (SBS) has initiated an investigation into Sionna Therapeutics, Inc. (NASDAQ: SION) for potential securities law violations. This investigation follows a significant drop in Sionna's share price after its SION-719 Phase 2a trial failed to meet its primary endpoint of sweat chloride reduction. SBS is inviting shareholders who suffered losses to participate in the investigation to discuss their rights.

FinanceFinancial MarketsLife Sciences
Published
16 Aug 2026 21:42
News subject
Regulatory and legal
Why this score
Legal or regulatory risk, Failed To Meet
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 59/100
30-day weight
6.6% of the score ยท 18.5d old
Duplicates
1 consolidated
#1530Tone
MarketBeatDirect company coverageStored article

Sionna Therapeutics (NASDAQ:SION) Lowered to Strong Sell Rating by Wall Street Zen

Wall Street Zen downgraded Sionna Therapeutics (NASDAQ:SION) to a "strong sell" rating. This comes amidst broader analyst sentiment leaning towards "hold," with the stock opening significantly below its 52-week high and reporting a quarterly loss that missed estimates. Insider selling has occurred, though some institutional investors increased their positions.

EarningsFinancial MarketsLife Sciences
Published
15 Aug 2026 05:42
News subject
Analyst action
Why this score
Sell Rating, Missed expectations
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 44/100
30-day weight
0.2% of the score ยท 20.1d old
Duplicates
1 consolidated
#1643Tone
Simply Wall St.Direct company coverageScored from headline

Sionna Therapeutics (SION) Resets After Trial Miss, Is The Discount Now Too Deep?

Published
13 Aug 2026 09:11
News subject
Market update
Why this score
Negative financial language
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Low ยท 28/100
30-day weight
<0.1% of the score ยท 22.0d old
Duplicates
1 consolidated
#18Not directional
Simply Wall St.Direct company coverageStored article

Sionna Therapeutics (SION) Is Down 86.8% After Halting SION-719 And Refocusing Its CF Pipeline โ€“ Has The Bull Case Changed?

Sionna Therapeutics (SION) experienced an 86.8% stock drop after discontinuing its lead cystic fibrosis candidate, SION-719, due to failing a Phase 2a trial. The company is now refocusing its pipeline on the SION-451 plus SION-2222 combination, aiming to preserve its US$268.30 million cash balance. This shift raises questions about the company's investment narrative and future clinical inflection points.

Financial MarketsLife Sciences
Published
13 Aug 2026 05:13
News subject
Balance sheet
Why this score
Negative market reaction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 22.2d old
Duplicates
1 consolidated
#1918Tone
PR NewswireDirect company coverageStored article

SION ALERT: Investigation Launched into Sionna Therapeutics, Inc., RGRD Law Attorneys Encourage Investors and Potential Witnesses to Contact Law Firm

Robbins Geller Rudman & Dowd LLP has initiated an investigation into Sionna Therapeutics, Inc. (NASDAQ: SION) following a significant drop in its stock price. The investigation stems from the company's announcement on August 10, 2026, that its SION-719 Phase 2a trial failed to meet a key activity endpoint, causing Sionna Therapeutics stock to fall over 91%. Investors who suffered losses and have information are encouraged to contact the law firm for potential securities fraud litigation.

FinanceFinancial MarketsLife Sciences
Published
12 Aug 2026 22:03
News subject
Regulatory and legal
Why this score
Legal or regulatory risk, Large negative market reaction, Failed To Meet, Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 62/100
30-day weight
4.8% of the score ยท 22.5d old
Duplicates
1 consolidated
#2043Tone
Simply Wall St.Direct company coverageScored from headline

Sionna Therapeutics (SION) Stock Still Looks Cheap After The 90% Fall

Published
12 Aug 2026 10:12
News subject
Market update
Why this score
Negative financial language
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Low ยท 28/100
30-day weight
<0.1% of the score ยท 23.0d old
Duplicates
1 consolidated
#2142Tone
MarketBeatDirect company coverageStored article

Sionna Therapeutics (NASDAQ:SION) Lowered to Hold Rating by JonesTrading

JonesTrading has downgraded Sionna Therapeutics (NASDAQ:SION) from a "strong buy" to a "hold" rating following the failure of its lead cystic fibrosis drug, SION-719, to meet its primary endpoint in a Phase 2 trial. This setback led to a significant stock price drop and numerous analyst downgrades, raising concerns about the company's future pipeline and financial needs. The stock currently holds a consensus "hold" rating with an average price target of $42.22, significantly higher than its current trading price of $5.10.

EarningsFinancial MarketsLife Sciences
Published
12 Aug 2026 10:39
News subject
Analyst action
Why this score
Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Low ยท 31/100
30-day weight
<0.1% of the score ยท 22.9d old
Duplicates
1 consolidated
#23Not directional
simplywall.stDirect company coverageScored from headline

Why Sionna Therapeutics (SION) Is Down 90.9% After Ending SION-719 Add-On To Trikafta Therapy

Published
11 Aug 2026 20:45
News subject
Market update
Why this score
The headline reports news without a clear direction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 23.5d old
Duplicates
1 consolidated
#2443Tone
FinancialContentDirect company coverageStored article

Sionna Therapeutics, Inc. - Common Stock (SION) Stock Price, News, Quote & History

Sionna Therapeutics (SION) halted development of SION-719 after its Phase 2a study failed to meet the key activity endpoint for cystic fibrosis treatment, despite initially showing promise. The company is now focusing on the SION-451 combination path. This news follows previous reports on financial results, investor conferences, and insider stock transactions.

EarningsFinancial MarketsLife Sciences
Published
11 Aug 2026 20:41
News subject
Earnings
Why this score
Failed To Meet
Company focus
Shared story ยท 78%
How it is used
Direct company coverage
Story strength
Low ยท 29/100
30-day weight
0.4% of the score ยท 23.5d old
Duplicates
1 consolidated
#2538Tone
StocksToTradeDirect company coverageStored article

SION Stock Slides, Then Snaps Back As Traders Eye Volatility

Sionna Therapeutics Inc. (SION) stock experienced significant volatility, plunging from mid-$50s to around $5 before bouncing back intraday. Despite burning cash, the company boasts a strong balance sheet with $211.0M in cash and low debt, providing a substantial runway for its early-stage biotech strategy. Traders are closely monitoring SION for its price action, recognizing it as a volatile asset with clear technical levels and a substantial cash pile, making it a case study in market sentiment and technical trading.

EarningsFinancial MarketsLife Sciences
Published
11 Aug 2026 16:32
News subject
Earnings
Why this score
Negative market reaction
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 37/100
30-day weight
0.6% of the score ยท 23.7d old
Duplicates
1 consolidated
#2641Tone
GlobeNewswireDirect company coverageStored article

Sionna Therapeutics, Inc. (SION) Shares Plummet Following Clinical Trial Resultsโ€”Johnson Fistel Investigates

Johnson Fistel, PLLP is investigating Sionna Therapeutics, Inc. (SION) for potential violations of federal securities laws after the company's shares plummeted following disappointing Phase 2a clinical trial results for SION-719. The trial failed to show meaningful improvement in cystic fibrosis, leading Sionna to halt further development of SION-719 as an add-on therapy. The investigation will examine whether investors suffered losses due to misleading statements or omissions regarding SION-719's potential.

EarningsFinanceFinancial MarketsLife Sciences
Published
11 Aug 2026 14:41
News subject
Regulatory and legal
Why this score
Legal or regulatory risk
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Low ยท 35/100
30-day weight
1.6% of the score ยท 23.8d old
Duplicates
1 consolidated
#2716Tone
QuartzDirect company coverageStored article

Sionna Therapeutics stock falls 92% after SION-719 trial failure

Sionna Therapeutics experienced a 92% stock drop after its experimental cystic fibrosis drug, SION-719, failed to meet its key endpoint in a Phase 2a trial. The company will not advance SION-719 as an add-on therapy and is evaluating its SION-451 program, while considering workforce reductions to protect its cash runway. This outcome was unexpected by the company, which continues to analyze the data.

EarningsFinancial MarketsLife Sciences
Published
11 Aug 2026 13:14
News subject
Earnings
Why this score
Large negative market reaction, Negative market reaction, Failed To Meet
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
High ยท 62/100
30-day weight
1.3% of the score ยท 23.8d old
Duplicates
1 consolidated
#2857Tone
BitgetDirect company coverageStored article

SIONNA THERAPEUTICS, INC. : WEDBUSH CUTS TO NEUTRAL FROM OUTPERFORM; CUTS TARGET PRICE TO $5 FROM $53

Wedbush has downgraded Sionna Therapeutics Inc. (SION.O) from Outperform to Neutral and significantly cut its target price from $53 to $5. This revision reflects a more cautious outlook from the analyst firm regarding the biopharmaceutical company's prospects.

Financial MarketsLife Sciences
Published
11 Aug 2026 12:41
News subject
Analyst action
Why this score
Positive financial language
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Low ยท 28/100
30-day weight
<0.1% of the score ยท 23.9d old
Duplicates
1 consolidated
#29Not directional
MT NewswiresDirect company coverageScored from headline

BTIG Downgrades Sionna Therapeutics to Neutral From Buy

Published
11 Aug 2026 11:36
News subject
Market update
Why this score
The headline reports news without a clear direction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 23.9d old
Duplicates
1 consolidated
#30Not directional
Simply Wall St.Direct company coverageStored article

Sionna Therapeutics (SION) Halts Lead Cystic Fibrosis Drug After Phase 2 Failure

Sionna Therapeutics (SION) has stopped development of its lead cystic fibrosis drug candidate after it failed a Phase 2 trial. This setback removes a key near-term catalyst for the company and shifts its focus to earlier-stage pipeline programs, increasing the importance of its remaining drug candidates and its cash management. The company will now decide on the future of its SION 451 plus SION 2222 combination after reviewing Phase 1 data.

EarningsLife Sciences
Published
11 Aug 2026 08:12
News subject
Earnings
Why this score
The headline reports news without a clear direction
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 24.0d old
Duplicates
1 consolidated

Earlier company news

SION news archive

37 older headlines

Stored newest first for historical research. It starts after the newest three pages above and then continues through older news. Each archive page is loaded only when it is opened.

Older news is kept in the archive

There are 37 older SION headlines. Open one page at a time when you need them.

Open older archive

Provider matches checked

Provider mentions not used in the score

6 not scored

A news provider linked these stories to SION, but the headline and available text are not mainly about Sionna Therapeutics, Inc. Common Stock. They are kept here for transparency and do not affect the score, confidence, history or wider market totals.

Provider mentions are kept separate

Open the list to see which provider matches were checked and left out of SION sentiment.

Open provider mentions

How the page works

How to read the score

The score shows direction

It describes the weighted balance of qualifying headlines. A score of 50 can mean balanced news or that there is not enough evidence; the status label explains which.

Confidence is separate

Confidence measures depth, source breadth, direct relevance, freshness and agreement. It does not rise merely because the tone is extreme.

Price is confirmation

Weekly price response, trend and fair-value position test whether the market is accepting or rejecting the news. They never rewrite the news score.

What the page does

It measures news already published. It is not a forecast, recommendation or price target.

Evidence context