NAUT NASDAQ Week ended 07 Aug 2026

Weekly Investor Report

Nautilus Biotechnology Inc · Healthcare · Biotechnology

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Latest close 0.90 USD
-7.9% latest week
Weekly setup

Weak trend

The weekly trend is not active. Price is -61.3% below the Trend Line and sits at 7.6% of its 52-week range. The latest completed week returned -7.9%, after a -52.4% four-week move. The latest factor snapshot indicates quality ranks weakly versus its universe; growth ranks weakly; valuation is neither clearly cheap nor expensive. Options positioning is bullish with 36/100 conviction, while the latest news-sentiment score is 49/100.

Setup score 25 out of 100
Latest Close 0.90 USD 7 Aug 2026
1W Return -7.9% latest completed week
4W Return -52.4% short-term follow-through
12W Return -64.1% quarterly tape
Trend Breadth 67.3% 35 of 52 weeks active
Volume Ratio 1.5x vs 13-week average
What is working
  • No strong opportunity cluster is confirmed yet; monitor trend and activity pressure.
What could go wrong
  • The trend backdrop is inactive, so price action has not confirmed a constructive regime.
  • Price is below the Trend Line, which keeps downside pressure in focus.
  • Price is below Fair Value, so the market is still discounting the latest tape.
  • Activity pressure is negative, which weakens the current setup.
What to watch next
  • Trend Line remains the key weekly regime level.
  • Activity pressure is the gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through -7.9% Latest completed week; four-week move -52.4%. Indicator stack 37/25 Trend and activity pressure are weighted against the latest 12-week confirmation window. Trend backdrop Active The trend backdrop defines the current weekly regime. Patient Capital Quiet Activity-pressure buy-signal status for institutional accumulation timing. Next-Week Expectancy Negative 39.85% Historical one-week expectancy contributes to the evidence score when direction is confirmed. Options pressure Bullish 36/100 conviction; expected move 180.5%. News sentiment 49/100 15 relevant articles in the latest sentiment read. Event risk 30 Jul Latest stored earnings date was 30 Jul 2026.
01 · Price action

Where price is—and whether the trend supports it

The weekly trend is not active. Price is -61.3% below the Trend Line and sits at 7.6% of its 52-week range. The latest completed week returned -7.9%, after a -52.4% four-week move.

Study the full chart

52-week price path

Price vs Trend Line and Fair Value
Price Trend Line Fair Value
02 · Volume and demand

Is real participation confirming the move?

Latest weekly volume is 1.5x the 13-week average. Participation is unusually strong and confirms that the move is attracting attention.

26-week volume confirmation

Bar height shows volume; colour shows the weekly price direction
13 Feb 20 Feb 27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 3 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun 19 Jun 26 Jun 3 Jul 10 Jul 17 Jul 24 Jul 31 Jul 7 Aug
Up week Down week
Demand beneath price

Activity pressure and institutional-style signals

These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.

Activity pressure path

Latest 0.1512-week average 0.42

12-week confirmation

Trend active4/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure0/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership5/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.15Current proprietary activity-pressure read.
Buy signals0Accumulation signal count in the latest 12 weeks.
Reversal markers0No reversal markers

No recent accumulation markers. No reversal markers.

03 · Momentum and leadership

Is performance persistent—and is the stock leading?

Performance is -52.4% over four weeks, -64.1% over 12 weeks, and 23.1% over one year. The current trend has remained active for 0 consecutive weeks.

Performance by holding period

1W-7.9%
4W-52.4%
12W-64.1%
26W-55.7%
52W23.1%
Active trend streak0 weeks
Active weeks in one year35
Trend breadth67.3%

Activity pressure vs relative leadership

Activity pressureRelative leadership
Pressure-1.25Latest activity-pressure read.
Pressure change-26.1%Four-week change in activity pressure.
Leadership-58.67Latest relative-leadership reading.
RS change-380.6%Four-week change in relative leadership.
04 · Fundamentals and valuation

What investors are paying for—and the quality behind it

The latest factor snapshot indicates quality ranks weakly versus its universe; growth ranks weakly; valuation is neither clearly cheap nor expensive.

Open full factor analysis
Factor week 09 Aug 2026 Financial statements through 30 Jun 2026 Field coverage 82% Model confidence 82%

Relative factor standing

Higher display scores are better. Each score is converted from the underlying universe rank, where rank 1 is best.

Overall factor strength19/100Blend of value, momentum, and quality. Underlying universe rank 82; rank 1 is best.
Value33/100Relative valuation strength. Underlying universe rank 68; rank 1 is best.
Quality1/100Profitability and accounting quality. Underlying universe rank 100; rank 1 is best.
Momentum74/100Medium-term price momentum. Underlying universe rank 27; rank 1 is best.
Growth10/100Revenue and earnings growth. Underlying universe rank 91; rank 1 is best.
How to read this

Quality and valuation are separate questions

A strong company can still carry a demanding valuation. This report shows profitability, growth, balance-sheet strength, and the price paid for those characteristics separately.

Valuation

How much investors are paying for earnings, sales, and cash flow.

P/E
-
Price divided by trailing earnings.
Price / sales
602.0x
Market value relative to trailing revenue.
EV / EBITDA
-
Enterprise value relative to operating cash earnings.
Free-cash-flow yield
-37.7%
Free cash flow as a share of enterprise value.

Business quality

Margins and the return generated on invested capital.

Gross margin
-1771.6%
Gross profit retained from each unit of revenue.
Operating margin
-31425.3%
Operating profit retained from revenue.
Free-cash-flow margin
-25583.7%
Free cash flow generated from revenue.
Return on invested capital
-30.7%
Operating return generated on invested capital.

Growth and financial strength

Recent business growth and accounting strength.

Revenue growth
-98.0%
Latest one-year revenue growth.
EPS growth
-
Latest one-year earnings-per-share growth.
Free-cash-flow growth
-
Latest one-year free-cash-flow growth.
Piotroski F-score
1/9
Nine-point accounting-strength checklist.

Shareholder return and balance sheet

Cash returned to owners and financial leverage.

Dividend yield
-
Cash dividends relative to market value.
Buyback yield
-1.3%
Net share repurchases relative to market value.
Shareholder yield
-1.3%
Dividend yield plus net buyback yield.
Net debt / EBITDA
-0.3x
Balance-sheet debt relative to operating cash earnings.
05 · Ownership, options, and sentiment

What other market participants are doing

Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.

Options positioningBullish

NAUT shows bullish options pressure with a 36/100 conviction score, put-call volume ratio of 0.56, expected move of 180.5%, and Sharemaestro trend signal inactive.

Conviction36/100
Expected move180.5%
Put/call volume0.56
Pressure39
Speculation33
Volatility96
Trend agreement12
Open options detail
Insider activity5 / 2

5 acquisitions and 2 disposals in the latest 180-day insider tape.

Acquisitions / disposals over the latest 180 days. Insider activity is context, not a stand-alone signal.
News sentiment49/100

Weighted news tone is neutral across 15 relevant articles.

3 positive · 9 neutral · 3 negative
Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal
06 · Catalysts and risk

What can move the shares—and how volatile the path has been

Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.

Next earnings30 JulLatest stored earnings date was 30 Jul 2026.
Options expected move180.5%Nearest-chain priced movement where available.
52-week drawdown-79.1%Distance below the 52-week high.
13-week volatility12.4%Standard deviation of weekly returns.

Weekly gains and losses

Latest 26 completed weeks

Each bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.

Weeks higher11 of 2615 weeks finished lower.
Best week+30.0%Week of 20 Mar.
Worst week-42.2%Week of 31 Jul.
Latest week-7.9%Week of 7 Aug.

Shape of recent returns

Strong gains6
Modest gains5
Flat weeks0
Modest losses2
Sharp losses13
Recent vol12.4%13-week weekly-return volatility.
Base vol12.6%52-week weekly-return volatility.
Up/down split26/26Count of positive and negative weeks in the 52-week window.
Average skew10.6% / -8.1%Average positive week versus average negative week.
07 · Sector and peer context

Is this stock leading—or simply moving with its group?

Sector and industry breadth distinguish company-specific strength from a broad group move.

08 · Evidence and weekly data

The underlying research record

Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.

Weekly tape28/100

Trend, activity pressure, participation, and risk combine to a 28/100 tape read.

 Indicator analysis27/100

Latest 12-week confirmation: trend 4/12, activity pressure 0/12, relative leadership 5/12.

Activity pressure 0.15; No reversal markers Next-Week ExpectancyNegative 39.85%

Next-week expectancy is negative with a 39.85% historical one-week setup read.

Adds short-term historical context without overriding trend, activity, or relative leadership. Factors29/100

O'Shaughnessy factor stack blends value, quality, momentum, and confidence.

Buyback Yield rank 77; Small Cap Core rank 75 Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal Options43/100

NAUT shows bullish options pressure with a 36/100 conviction score, put-call volume ratio of 0.56, expected move of 180.5%, and Sharemaestro trend signal inactive.

Bullish · Call-side pressure · Expected move 180.5% Sentiment49/100

Weighted news tone is neutral across 15 relevant articles.

Biotechnology Stocks To Watch As Investors Look Past Pfizer’s Covid Revenue Drop Insiders5 / 2

5 acquisitions and 2 disposals in the latest 180-day insider tape.

 Earnings30 Jul

Latest stored earnings date was 30 Jul 2026.
WeekCloseReturnTrend LineFair ValuePressureLeadershipVolumeTrend
7 Aug 20260.90 USD-7.9%2.32 USD2.11 USD-1.25-58.675.9MOff
31 Jul 20260.98 USD-42.2%2.36 USD2.13 USD-1.19-52.876.5MOff
24 Jul 20261.69 USD-2.9%2.39 USD2.14 USD-1.18-18.002.3MOff
17 Jul 20261.74 USD-7.9%2.40 USD2.15 USD-1.02-16.323.2MOff
10 Jul 20261.89 USD9.2%2.41 USD2.16 USD-0.99-12.216.4MOff
3 Jul 20261.73 USD-13.5%2.41 USD2.17 USD-1.02-17.556.1MOff
26 Jun 20262.00 USD-12.3%2.42 USD2.18 USD-0.97-3.269.4MOff
19 Jun 20262.28 USD1.8%2.43 USD2.19 USD-0.946.411.5MOff
12 Jun 20262.24 USD-6.3%2.43 USD2.20 USD-0.818.582.0MOn
5 Jun 20262.39 USD-12.8%2.41 USD2.21 USD-0.6219.952.2MOn
29 May 20262.74 USD7.9%2.38 USD2.22 USD-0.5033.081.8MOn
22 May 20262.54 USD1.2%2.33 USD2.22 USD-0.3528.952.1MOn
15 May 20262.51 USD-6.3%2.29 USD2.22 USD-0.1730.902.9MOn
8 May 20262.68 USD-0.7%2.24 USD2.22 USD0.1341.271.2MOn
How to use this report

This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.

Evidence context