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๐Ÿ‡บ๐Ÿ‡ธ NASDAQ ยท Healthcare ยท Biotechnology

TIL beta and relative strength

Instil Bio Inc.

TIL is recovering from below benchmark with lower sensitivity to QQQ.

Week ending Latest completed weekly edition
Next update 15:40 UK ยท after Stage Analysis
One-year beta 0.16Lower sensitivity ยท Rising
Movement explained 0%5% weekly correlation
Relative strength-41.02Recovering from below benchmark
Downside beta 0.09Upside beta 0.48
One-year excess return-97.1%-71.9% stock ยท 25.2% benchmark
Directional participation

TIL in rising and falling QQQ weeks

These percentages count what actually happened in completed weeks. They describe historical participation, not certainty about the next move.

Latest 52-week reading More dependable when the benchmark falls

The stock has joined falling benchmark weeks more consistently than rising ones.

59% of directional weeks moved the same way.
When QQQ rose48%

TIL also rose in 48% of 29 rising benchmark weeks.

When QQQ fell70%

TIL also fell in 70% of 23 falling benchmark weeks.

Market state now Range-bound market with active movement
-0.5% over 13 weeks21.8% volatility

After 17 earlier matches by direction and movement level, directional participation is mixed.

Joined rising weeks54%
Joined falling weeks25%
Limited sample ยท 47% same-direction rate ยท 18.59 beta
Benchmark fit

TIL sensitivity to QQQ

The benchmark relationship is weak and explains 0% of weekly movement over the latest year. Current beta is 0.16 and is rising.

Likely beta range-0.80 to 1.12

A wider range means the beta estimate is less precise.

Beta stability34/100

How consistently rolling beta has held its level and direction.

Annualised alpha-106.6%

The weekly regression intercept annualised; it is historical, not expected return.

Tracking error65.0%

Annualised volatility of returns above or below the benchmark.

Relationship directionRelationship strengthening

+14.0 point change in movement explained across two distinct 26-week windows.

Beta and benchmark fitBeta is secondary evidence only
Weaker benchmark fitStronger benchmark fitLower sensitivityHigher sensitivity

The benchmark fit is too weak for the headline beta to be treated as a dependable description on its own.

Historical one-week sensitivity
If QQQ rises 1%+0.48%historically associated TIL move
If QQQ falls 1%-0.09%historically associated TIL move
Likely beta range -0.80 to 1.12 ยท width 1.92
Can the beta be trusted?Weak relationship
Movement explained0%
Stability34%
Directional agreement59%

Rolling beta

26-week estimates show whether market sensitivity is rising or falling.

Move across the chart to inspect a completed week.
Rolling betaMarket-like beta 1.00

Rolling relationship strength

Correlation shows direction; explained movement shows how useful the relationship has been.

Move across the chart to inspect a completed week.
CorrelationMovement explained
PeriodBetaCorrelationMovement explainedAlphaExcess returnTracking error
6 months0.5641%17%-52.5%-34.6%28.8%
1 year0.165%0%-106.6%-97.1%65.0%
2 years3.9122%5%+79.7%-94.1%354.5%
3 years2.9119%4%+58.6%-115.5%292.0%
5 years2.3521%5%-15.8%-193.4%232.1%
Relative strength

TIL relative strength against QQQ

The score compares the stock/benchmark ratio with its trailing 52-week average. Above zero means the ratio is above trend; direction shows whether that advantage is building or fading.

Relative-strength trend

Current score -41.02 ยท 13-week change +18.20

Move across the chart to inspect a completed week.
Relative strengthZero baseline

Stock, benchmark and worthwhile peers

Each path starts at 100. Sector and industry appear only when their Market Structure indexes have enough constituents.

Move across the chart to inspect a completed week.
Sector ยท Healthcare-14.7 points

versus sector over 13 weeks ยท 948 constituents ยท 16% correlation

Industry ยท Biotechnology-12.2 points

versus industry over 13 weeks ยท 529 constituents ยท 20% correlation

Sensitivity to Healthcare0.50 beta

3% of weekly movement explained by the sector over one year.

Sensitivity to Biotechnology0.51 beta

4% of weekly movement explained by the industry over one year.

Return components

13-week and 52-week returns relative to QQQ

This is a return bridge, not a claim of cause. It starts with the benchmark return, then shows the difference added at sector, industry and ticker level.

Last 13 weeks-6.9 points vs benchmark
Broad market-0.5%
Sector difference+7.9%
Industry difference-2.5%
Ticker difference-12.2%

The largest source of relative weakness was the ticker difference. TIL returned -7.3%; QQQ returned -0.5%.

Last 52 weeks-97.1 points vs benchmark
Broad market+25.2%
Sector difference-15.5%
Industry difference+8.1%
Ticker difference-89.7%

The largest source of relative weakness was the ticker difference. TIL returned -71.9%; QQQ returned 25.2%.

Market conditions

TIL in rising and falling benchmark weeks

Upside beta is higher than downside beta, a historically favourable split.

Upside beta0.48-81% upside capture
Downside beta0.09116% downside capture
Current splitMore responsive in rising markets+0.39 beta gap
ConditionWeeksTIL averageQQQ averageBetaBeat benchmark
Benchmark up29-1.86%+2.29%0.4828%
Benchmark down23-2.13%-1.84%0.0957%
Strongest benchmark weeks10+0.88%+4.05%2.2910%
Weakest benchmark weeks10-1.44%-3.12%3.1670%
Quieter benchmark weeks26-0.99%+0.23%0.4646%
Historical extremes

Strongest and weakest 13-week relative periods

Distinct 13-week windows prevent one long move from filling the list with overlapping dates.

Strongest relative periods

2024-06-21 to 2024-09-13+710.2 pts

TIL 709.6% ยท QQQ -0.6%

The return pattern shows that the ticker moved beyond its peer backdrop.
2025-05-02 to 2025-07-25+128.0 pts

TIL 148.0% ยท QQQ 20.0%

The return pattern shows that the industry added to the move, and the ticker moved beyond its peer backdrop.
2023-12-22 to 2024-03-15+72.3 pts

TIL 79.6% ยท QQQ 7.3%

The return pattern shows that the industry added to the move, and the ticker moved beyond its peer backdrop.

Weakest relative periods

2022-10-21 to 2023-01-13-90.6 pts

TIL -82.5% ยท QQQ 8.0%

The return pattern shows that the industry added to the move, and the ticker moved beyond its peer backdrop.
2024-09-20 to 2024-12-13-85.8 pts

TIL -74.0% ยท QQQ 11.8%

The return pattern shows that the sector moved the same way, and the industry added to the move, and the ticker moved beyond its peer backdrop.
2025-09-12 to 2025-12-05-74.0 pts

TIL -65.3% ยท QQQ 8.7%

The return pattern shows that the ticker moved beyond its peer backdrop.
Pressure and timing

Drawdowns and lead/lag relationship

The strongest link is in the same week. Lead/lag evidence is treated as secondary because timing relationships can change quickly.

Drawdown from each rolling high

Worst available drawdown: TIL -98.6% ยท QQQ -35.1%

Move across the chart to inspect a completed week.
TIL drawdownQQQ drawdown
Ticker leads 2w
3%
Ticker leads 1w
0%
Same week
19%
Benchmark leads 1w
-15%
Benchmark leads 2w
-4%
Observable signals

Signals that would confirm or change the reading

These are conditions to monitor, not price targets or forecasts.

Relative strengthBelow the zero baseline

A sustained move above zero would mark a meaningful repair in the stock/benchmark ratio.

Up/down beta+0.39 upside-minus-downside gap

Upside beta is higher than downside beta. The favourable split remains intact while that gap stays positive.

Exposure trendBeta is rising

Rising beta means broad-market moves are carrying more weight; falling beta means ticker-specific forces are carrying more weight.

Peer confirmation-12.2 points versus Biotechnology over 13 weeks

Strength shared by the peer group is broader; strength confined to the ticker is more company-specific and usually less stable.

Method and limits

Data and interpretation limits

Data
Completed weekly observations from 2021-03-26 to 2026-08-21 ยท 283 aligned weeks.
Current reading
52 weeks; rolling charts use 26 weeks.
Relative strength
Stock/benchmark ratio compared with its trailing 52-week average.
Peer evidence
At least 10 sector constituents and 5 industry constituents. Thin groups are excluded.
Boundary
Historical relationship analysis, not a forecast or a statement of cause. Historical relationships can break without warning.

Evidence context