Sanofi's Oral TREM2 Agonist SAR448851 Advances to Phase 2 TREMHANCE Trial in Early Alzheimer Disease
Sanofi's oral TREM2 agonist, SAR448851, is progressing to a Phase 2 clinical trial named TREMHANCE for early Alzheimer's disease. The trial will evaluate the drug's efficacy and safety, with the primary endpoint being the change in plasma p-tau217 at week 48, aiming to shift …