Healthcare ยท Biotechnology ยท Completed evidence

CRSP relative to BEAM

Crispr Therapeutics AG is the relatively depressed leg. Beam Therapeuticsย Inc is the relatively extended leg.

Weekly separation 0.35ฯƒpercentile rank 62
Daily timing Gap stable-1.00ฯƒ latest
Relationship quality 89/100156 completed weeks
Evidence alignment 44/100depressed leg versus extended leg
Stability 92/10015 mean crossings
Break risk 13/100lower is more dependable
Specific pair strategy

What is the play in CRSP / BEAM?

This is a relative trade. The result depends on which security performs better, not on whether the whole market rises or falls.

No active pair setup

Keep CRSP / BEAM on routine watch

The two securities are not far enough apart, with enough confirmation, to support a useful convergence case.

Potential long leg Long CRSP Crispr Therapeutics AG

This is the relatively depressed leg. The case needs it to recover or at least hold up better than the other leg.

Potential short leg Short BEAM Beam Therapeuticsย Inc

This is the relatively extended leg. The case needs it to lag or weaken relative to the long leg.

How the pair can make money

A favourable relative move means CRSP rises more than BEAM, falls less than BEAM, or rises while BEAM falls. If BEAM outperforms CRSP, the pair moves against the case.

What triggers it

A future case would need an unusual separation, a dependable relationship and evidence favouring CRSP over BEAM.

What keeps it valid

There is no reason to force a long or short leg while the relationship remains near normal.

What cancels the case

There is no active case to invalidate because no relative-value position is currently supported.

What would confirm the research case?

Keep the pair on the relationship map and wait for a meaningful, evidence-backed separation.

Evidence now

  • BEAM Market Dynamics is weakening.

What would invalidate it?

There is no current dislocation edge; transaction costs can dominate small spread movements.

Possible setup paths

How the relative-value idea could be expressed

These are research structures, not recommendations or position-size instructions. The current course above determines whether any structure is ready to study now.

Two-leg convergence structure

Long CRSP / short BEAM

Treat both legs as one relative position. The setup looks for CRSP to outperform BEAM; CRSP can rise faster, fall less, or rise while BEAM falls. The pair loses ground when BEAM outperforms CRSP.

When it becomes relevantThis is a structure to study only after the current course changes from โ€œNo setup at presentโ€ to confirmed convergence. A new, unusual separation would need to develop while the historical relationship remains dependable.Principal riskRequires a live review of both legs, borrow availability and cost, event dates, liquidity and the research normalisation.
Depressed-leg recovery study

Study CRSP alone if its own evidence confirms

This simpler expression focuses on recovery in CRSP. It avoids short-borrow mechanics, but it no longer isolates relative value: the result is exposed to the broad market, the sector and CRSP-specific news.

When it becomes relevantA stronger case needs improving CRSP price structure and supporting evidence, not just a wide relationship gap.Principal riskCarries full single-security and broad-market direction risk.
Extended-leg rollover study

Study BEAM alone if its support continues to weaken

This expression focuses on weakness in BEAM. It may fit a leader-rollover case, but it also abandons the relative hedge and adds direct market direction, squeeze and company-event risk.

When it becomes relevantWeakening in BEAM must be visible in its own completed evidence; relative extension alone is not enough.Principal riskShort selling can involve unlimited loss, borrow fees, recalls and forced close-outs.

Any practical expression needs an independent review of suitability, portfolio risk, liquidity, current news and earnings, borrow availability and cost, transaction costs and tax.

Relationship gap ยท technical name: standardised residual

How far apart are they compared with normal?

Zero is the pair's historical centre. The outer guides show increasingly unusual departures from it.

What this chart is

This is the relationship gap after allowing for the pair's usual co-movement. Zero is its historical centre; the distance is measured in standard deviations, so different pairs can be compared on the same scale.

What it says now

The latest gap is 0.35 standard deviations from normal. CRSP is the relatively depressed leg and BEAM is the relatively extended leg. That is unusual separation, not proof that either security is cheap or expensive.

What matters next

A move toward zero means convergence. A move farther from zero means the separation is extending and raises the risk that the old relationship is changing.

Historical standardised relationship residualThe line shows how far the relationship sat above or below its fitted centre over completed weekly observations.
Common-base price paths

Which security created the gap?

Both paths begin at 100 so their relative movement is visible without mixing different share prices.

What this chart is

Both securities are reset to 100 at the first date. This removes the distraction of different share prices and shows how their completed weekly price paths diverged. It is not a valuation chart.

What it says now

Since the common starting point, BEAM is +15.3% and CRSP is +7.8%. The chart shows which price path contributed to the separation; the fitted relationship measure is more precise than the raw visual distance.

What matters next

For convergence, watch for CRSP to catch up, BEAM to lose ground, or both. The relationship can close even if both securities rise or both fall.

Indexed completed weekly price pathsIndexed paths for both securities in the relationship, beginning at 100.
BEAMCRSP
Completed daily timing

Is the gap closing yet?

The daily relationship adds timing context inside the slower weekly case. It does not replace the weekly validity checks.

What this chart is

This applies the same relationship to completed daily bars. It is the timing layer inside the weekly case, not a separate trading signal.

What it says now

Gap stable: The completed daily gap is broadly unchanged. There is no clear short-term turn yet.

What matters next

A sustained move toward zero would add confirmation; continued flat action keeps the case on watch.

Completed daily standardised relationship residualThe daily path shows whether the current separation has narrowed or extended across the latest completed sessions.
Relatively depressed leg

CRSP ยท Crispr Therapeutics AG

17/100 evidence score
Market Dynamics
-0.45 ยท change -1.146
Trend
Negative
Stage
Stage 4 ยท Declining
Smart Money
Neutral
News sentiment
Neutral
Options
Mixed
Open CRSP research terminal โ†’
Relatively extended leg

BEAM ยท Beam Therapeuticsย Inc

29/100 evidence score
Market Dynamics
-1.168 ยท change -1.977
Trend
Positive
Stage
Stage 3 ยท Distribution
Smart Money
Neutral
Short interest
Crowded
Options
Volatility
Open BEAM research terminal โ†’
Relationship diagnostics

Why this pair is on the map

Return co-movement0.72

How closely completed weekly returns moved together across the measurement window.

Residual stability92/100

How consistent the fitted relationship remained across earlier and later parts of the sample.

Typical decay6.4 weeks

An observed mean-reversion clock, not a deadline or a forecast.

Mean crossings15

How often the residual crossed its historical centre; repeated crossings matter more than a single fit.

Spread percentile62th

The latest residual's location inside its own completed history.

Tradability context79/100

Stored price, volume and size context only. It does not include a live short locate or cost.

Held-out resolution 100%

2 of 2 non-overlapping historical separations resolved after the relationship was fitted on earlier data.

Typical resolution7.5 weeks

Median time to return near the earlier fitted centre among the held-out cases that resolved.

Worst extension+0.13ฯƒ

The largest further move recorded after a measured held-out separation, before resolution or the observation window ended.

State history

What changed and when

Daily timing changed

Completed daily timing changed to gap stable through 2026-08-18.

Daily timing changed

Completed daily timing changed to gap extending through 2026-08-17.

Relationship discovered

Published as Balanced relationship after the completed 2026-08-14 observation.

Same-industry map
Measure guide

Weekly separation

How far the latest completed weekly relationship sits from its own historical centre.

A larger reading means the two securities are unusually far apart relative to this relationship's completed history. It identifies a dislocation; it does not, by itself, predict convergence.

Measure guide

Daily timing

The direction of the gap across the latest completed daily sessions.

Narrowing means the daily gap has begun to close, extending means it has widened, and stable means the change is not yet material. The weekly relationship remains the primary research clock.

Measure guide

Relationship quality

A public summary of how dependable the completed historical relationship has been.

It brings together repeatability, stability and later-sample behaviour. Higher is stronger, but no score guarantees that a historical relationship will continue.

Measure guide

Evidence alignment

Whether the wider stored evidence supports the depressed leg relative to the extended leg.

The comparison uses published price structure and supporting research for both securities. Higher alignment means more of that evidence points in the same relative direction; construction weights are not disclosed.

Measure guide

Stability

How consistently the relationship held across earlier and later completed observations.

Higher stability means the relationship changed less across the sample. It is a durability check, not a forecast or a guarantee of mean reversion.

Measure guide

Break risk

The risk that the earlier relationship is no longer a dependable reference point.

Lower is better. A high reading warns that the separation may reflect new information or a structural change rather than a temporary gap.

Measure guide

Research normalisation

A common scale used to compare the two historical price paths.

It describes the fitted relationship for research. It is not a position size, hedge instruction or risk target, and it excludes live borrow, fees, slippage and portfolio constraints.

Measure guide

Held-out resolution

How often earlier measured separations later moved back near their fitted centre.

Each historical check is fitted only on information that came before it. The result is descriptive evidence from this relationship's history, not an expected return or future probability.

Evidence context