Composite setup radar
40
Balanced read
NASDAQ Equity Snapshot
IONS Weekly Equity Report
Ionis Pharmaceuticals Inc
Latest Close
73.28 USD
12 Jun 2026
1W Return
-1.6%
latest completed week
4W Return
-1.3%
short-term follow-through
12W Return
3.2%
quarterly tape
Trend Breadth
71.2%
37 of 52 weeks active
Volume Ratio
1.0x
vs 13-week average
Company Brief
What the company does
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.
Snapshot
What the weekly tape is saying
IONS closed the latest completed week at 73.28 USD. The 4-week return is -1.3% and the 12-week return is 3.2%. Trend Signal is inactive, Market Dynamics is -0.56. Setup signature: Balanced read with a 40/100 composite read.
Trend Signal
Inactive
Market Dynamics
No fresh buy
Price vs Trend
-5.4%
Volume
1.0x
Setup Cockpit
A compressed read of the whole setup
The radar blends trend persistence, momentum, Market Dynamics, Relative Strength, volume confirmation, and risk control into one weekly cockpit.
Scoreboard
Trend
39
Persistence of active Trend Signal over the last year and current streak.
Momentum
50
Blend of 4-week and 12-week follow-through.
Dynamics
43
Latest Market Dynamics and whether pressure has improved over four weeks.
Relative Strength
10
Relative leadership and short-term RS change.
Volume
42
Participation compared with the 13-week volume baseline.
Risk Control
58
Drawdown and recent weekly volatility pressure.
16-week signal tape
27 Feb
6 Mar
13 Mar
20 Mar
27 Mar
2 Apr
10 Apr
17 Apr
24 Apr
1 May
8 May
15 May
22 May
29 May
5 Jun
12 Jun
Weekly return bar
Trend Signal dot
Positive Market Dynamics dot
Price Action
Price, Trend Line, and Fair Value
Weekly price context with the latest close, trend position, Fair Value gap, drawdown, and 52-week range location.
52-week price path
Price
Trend Line
Fair Value
Price map
- Trend Line
- 77.46 USD
- Vs Trend Line
- -5.4%
- Fair Value
- 49.92 USD
- Vs Fair Value
- 46.8%
- 52W High
- 86.74 USD
- 52W Low
- 34.77 USD
- Drawdown
- -15.5%
- Range Position
- 74.1%
Momentum
Returns and trend persistence
Return windows separate the latest week from short-term and medium-term follow-through.
Return windows
Trend read
- Active Streak
- 0 weeks
- 52W Active Weeks
- 37
- 52W Active Breadth
- 71.2%
- Sector Scope
- US Healthcare
- Sector Rank
- 671 of 1038
- Sector Percentile
- 35.4%
Peer Context
Sector and industry pulse
Peer breadth helps separate a stock-specific move from a broader group rotation.
US Healthcare
- Tracked Peers
- 100
- 4W Rank
- 75 of 100
- Avg 1W
- 0.8%
- Avg 4W
- 3.5%
- Trend Breadth
- 33.0%
- Positive MD
- 41.0%
US Biotechnology
- Tracked Peers
- 100
- 4W Rank
- 58 of 100
- Avg 1W
- 4.9%
- Avg 4W
- 1.7%
- Trend Breadth
- 46.0%
- Positive RS
- 47.0%
Market Dynamics
Pressure, Relative Strength, and expectation
Market Dynamics and Relative Strength show whether buying pressure and relative leadership are confirming the price move.
Dynamics path
Market Dynamics
Relative Strength
Signal state
- Market Dynamics
- -0.56
- 4W MD Change
- 41.5%
- Relative Strength
- -8.31
- 4W RS Change
- -183.0%
- Expectation
- Undecided
- Probability
- 54.60%
Volume
Participation and confirmation
Volume tells us whether the latest weekly move is being confirmed by unusual participation.
52-week volume profile
Volume map
- Latest Volume
- 9.0M
- 13W Average
- 9.0M
- 52W Average
- 10.7M
- Vs 13W
- 1.0x
- Vs 52W
- 0.8x
Risk Anatomy
Volatility, downside weeks, and return shape
A compact risk profile shows whether the move is steady, volatile, or being driven by sharp one-week jumps.
26-week return distribution
Risk map
- 13W Volatility
- 2.0%
- 52W Volatility
- 7.0%
- Upside Weeks
- 30
- Downside Weeks
- 22
- Downside Breadth
- 42.3%
- Avg Gain / Loss
- 4.8% / -2.7%
Context
Classification, opportunities, risks, and watch points
Top-level read across company classification, constructive evidence, caution points, and the next things that matter.
Classification
- Exchange
- NASDAQ
- Country
- US
- Sector
- Healthcare
- Industry
- Biotechnology
- Currency
- USD
- Market Cap
- 12.5B
Opportunity signals
- Price is above Fair Value, showing premium demand versus the model.
Risk signals
- Trend Signal is inactive, so price action has not confirmed a constructive regime.
- Price is below the Trend Line, which keeps downside pressure in focus.
- Market Dynamics is negative, which weakens the current setup.
Watch next
- Trend Line remains the key weekly regime level.
- Market Dynamics is the pressure gauge to monitor for confirmation or fade.
- A volume ratio above 1.5x would show stronger participation in the next move.
Weekly Tape
Recent completed weeks
The latest weekly rows behind the report snapshot.
| Week | Close | Return | Trend | Fair Value | MD | RS | Volume | Signal |
|---|---|---|---|---|---|---|---|---|
| 12 Jun 2026 | 73.28 USD | -1.6% | 77.46 USD | 49.92 USD | -0.56 | -8.31 | 9.0M | Off |
| 5 Jun 2026 | 74.48 USD | -2.6% | 77.40 USD | 49.71 USD | -0.79 | -4.09 | 8.1M | Off |
| 29 May 2026 | 76.50 USD | 1.2% | 77.37 USD | 49.49 USD | -0.89 | -5.28 | 5.9M | Off |
| 22 May 2026 | 75.56 USD | 1.8% | 77.30 USD | 49.27 USD | -0.85 | -3.08 | 9.6M | Off |
| 15 May 2026 | 74.23 USD | -2.0% | 77.14 USD | 49.05 USD | -0.96 | -2.94 | 8.2M | Off |
| 8 May 2026 | 75.71 USD | 0.6% | 77.10 USD | 48.82 USD | -0.93 | -0.61 | 7.9M | Off |
| 1 May 2026 | 75.28 USD | 2.7% | 76.91 USD | 48.57 USD | -0.98 | 5.01 | 12.6M | Off |
| 24 Apr 2026 | 73.27 USD | -3.2% | 76.71 USD | 48.32 USD | -1.15 | 4.63 | 8.1M | Off |
| 17 Apr 2026 | 75.71 USD | 0.7% | 76.40 USD | 48.07 USD | -1.15 | 11.58 | 8.1M | Off |
| 10 Apr 2026 | 75.17 USD | 0.5% | 75.91 USD | 47.82 USD | -1.17 | 18.78 | 6.6M | Off |
| 2 Apr 2026 | 74.79 USD | 3.7% | 75.51 USD | 47.58 USD | -1.17 | 24.87 | 7.4M | Off |
| 27 Mar 2026 | 72.15 USD | 1.6% | 75.06 USD | 47.34 USD | -1.14 | 26.77 | 12.9M | Off |
| 20 Mar 2026 | 70.99 USD | -0.3% | 74.08 USD | 47.11 USD | -0.99 | 22.13 | 12.6M | Off |
| 13 Mar 2026 | 71.19 USD | -3.8% | 73.13 USD | 46.87 USD | -0.82 | 21.32 | 12.3M | On |