- The trend backdrop is active with a 16-week active streak.
- Price is above the Trend Line, keeping the weekly tape constructive.
- Price is above Fair Value, showing premium demand versus the model.
- Activity pressure is positive on the latest completed week.
7427
TWO
Week ended 14 Aug 2026
Weekly Investor Report
Great Novel Therapeutics Biotech & Medicals · Healthcare · Biotechnology
Latest close
71.50 TWD
2.4%
latest week
Weekly setup
Constructive, but selective
The weekly trend is active. Price is 69.4% above the Trend Line and sits at 79.2% of its 52-week range. The latest completed week returned 2.4%, after a 5.9% four-week move. Near-term considerations: volume confirmation is below normal.
Setup score
61
out of 100
Latest Close
71.50 TWD
14 Aug 2026
1W Return
2.4%
latest completed week
4W Return
5.9%
short-term follow-through
12W Return
81.0%
quarterly tape
Trend Breadth
44.2%
23 of 52 weeks active
Volume Ratio
0.7x
vs 13-week average
- Next-week expectancy is negative at 42.52% based on similar historical setup states.
- Trend Line remains the key weekly regime level.
- Activity pressure is the gauge to monitor for confirmation or fade.
- A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through
2.4%
Latest completed week; four-week move 5.9%.
Indicator stack
69/80
Trend and activity pressure are weighted against the latest 12-week confirmation window.
Trend backdrop
Active
The trend backdrop defines the current weekly regime.
Patient Capital
Recent
Activity-pressure buy-signal status for institutional accumulation timing.
Next-Week Expectancy
Negative 42.52%
Historical one-week expectancy contributes to the evidence score when direction is confirmed.
01 · Price action
Study the full chart
Where price is—and whether the trend supports it
The weekly trend is active. Price is 69.4% above the Trend Line and sits at 79.2% of its 52-week range. The latest completed week returned 2.4%, after a 5.9% four-week move.
52-week price path
Price vs Trend Line and Fair Value
Price
Trend Line
Fair Value
02 · Volume and demand
Is real participation confirming the move?
Latest weekly volume is 0.7x the 13-week average. Participation is below its recent norm, so price strength is not receiving full volume confirmation.
26-week volume confirmation
Bar height shows volume; colour shows the weekly price direction
13 Feb
27 Feb
6 Mar
13 Mar
20 Mar
27 Mar
3 Apr
10 Apr
17 Apr
24 Apr
1 May
8 May
15 May
22 May
29 May
5 Jun
12 Jun
19 Jun
26 Jun
3 Jul
10 Jul
17 Jul
24 Jul
31 Jul
7 Aug
14 Aug
Up week
Down week
Demand beneath price
Activity pressure and institutional-style signals
These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.
Activity pressure path
Latest 0.8312-week average 0.66
12-week confirmation
Trend active12/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure12/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership5/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.83Current proprietary activity-pressure read.
Buy signals1Accumulation signal count in the latest 12 weeks.
Reversal markers0No reversal markers
No recent accumulation markers. No reversal markers.
03 · Momentum and leadership
Is performance persistent—and is the stock leading?
Performance is 5.9% over four weeks, 81.0% over 12 weeks, and 102.5% over one year. The current trend has remained active for 16 consecutive weeks.
Performance by holding period
Active trend streak16 weeks
Active weeks in one year23
Trend breadth44.2%
Activity pressure vs relative leadership
Activity pressureRelative leadership
Pressure1.53Latest activity-pressure read.
Pressure change34.5%Four-week change in activity pressure.
Leadership36.32Latest relative-leadership reading.
RS change-5.7%Four-week change in relative leadership.
04 · Fundamentals and valuation
Open full factor analysis
What investors are paying for—and the quality behind it
A published fundamentals and factor snapshot is not available for this company.
No published fundamental snapshot is available for this company.
05 · Ownership, options, and sentiment
What other market participants are doing
Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.
Insider activity-
No recent insider transactions are stored for this company.
News sentiment-
No current sentiment snapshot is stored.
Patient CapitalRecent
Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.
Recent buy signal in the last 8 weeks
06 · Catalysts and risk
What can move the shares—and how volatile the path has been
Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.
Next earnings-No event is currently stored.
Options expected move-Nearest-chain priced movement where available.
52-week drawdown-13.6%Distance below the 52-week high.
13-week volatility13.0%Standard deviation of weekly returns.
Weekly gains and losses
Latest 26 completed weeksEach bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.
13 Feb
20 Mar
17 Apr
15 May
12 Jun
10 Jul
14 Aug
Weeks higher10 of 2616 weeks finished lower.
Best week+39.9%Week of 24 Apr.
Worst week-9.8%Week of 31 Jul.
Latest week+2.4%Week of 14 Aug.
Shape of recent returns
Strong gains7
Modest gains3
Flat weeks0
Modest losses11
Sharp losses5
Recent vol13.0%13-week weekly-return volatility.
Base vol10.5%52-week weekly-return volatility.
Up/down split20/32Count of positive and negative weeks in the 52-week window.
Average skew11.1% / -3.9%Average positive week versus average negative week.
07 · Sector and peer context
Is this stock leading—or simply moving with its group?
Sector and industry breadth distinguish company-specific strength from a broad group move.
SectorTW Healthcare
4-week rank20 / 100
Group average0.1%
Trend breadth34.0%
Trend34.0%active weekly trend signals
MD60.0%positive activity pressure
RS9.0%positive relative leadership
Four-week leaders
IndustryTW Biotechnology
4-week rank10 / 96
Group average-2.7%
Trend breadth24.0%
Trend24.0%active weekly trend signals
MD39.6%positive activity pressure
RS6.2%positive relative leadership
Four-week leaders
08 · Evidence and weekly data
The underlying research record
Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.
Weekly tape58/100
Trend, activity pressure, participation, and risk combine to a 58/100 tape read.
Indicator analysis78/100Latest 12-week confirmation: trend 12/12, activity pressure 12/12, relative leadership 5/12.
Activity pressure 0.83; No reversal markers Next-Week ExpectancyNegative 42.52%Next-week expectancy is negative with a 42.52% historical one-week setup read.
Adds short-term historical context without overriding trend, activity, or relative leadership. Factors50/100No published factor snapshot is available yet.
Patient CapitalRecentActivity-pressure buy-signal evidence highlights potential institutional accumulation windows.
Recent buy signal in the last 8 weeks Sentiment50/100No sentiment snapshot is stored yet.
Insiders50/100No recent insider transaction evidence is stored.
Earnings50/100No stored earnings event is currently attached to this ticker.
| Week | Close | Return | Trend Line | Fair Value | Pressure | Leadership | Volume | Trend |
|---|---|---|---|---|---|---|---|---|
| 14 Aug 2026 | 71.50 TWD | 2.4% | 42.20 TWD | 45.44 TWD | 1.53 | 36.32 | 2.7M | On |
| 7 Aug 2026 | 69.80 TWD | 4.2% | 40.87 TWD | 45.49 TWD | 1.61 | 38.06 | 2.4M | On |
| 31 Jul 2026 | 67.00 TWD | -9.8% | 39.59 TWD | 45.61 TWD | 1.67 | 36.05 | 4.5M | On |
| 24 Jul 2026 | 74.30 TWD | 10.1% | 38.50 TWD | 45.75 TWD | 1.45 | 48.86 | 14.1M | On |
| 17 Jul 2026 | 67.50 TWD | 37.5% | 37.20 TWD | 45.90 TWD | 1.13 | 38.51 | 12.4M | On |
| 10 Jul 2026 | 49.10 TWD | 23.5% | 36.16 TWD | 46.11 TWD | 0.86 | -4.95 | 5.6M | On |
| 3 Jul 2026 | 39.75 TWD | 3.1% | 35.66 TWD | 46.43 TWD | 0.50 | -25.94 | 1.9M | On |
| 26 Jun 2026 | 38.55 TWD | -4.0% | 35.47 TWD | 46.86 TWD | 0.45 | -25.57 | 2.5M | On |
| 19 Jun 2026 | 40.15 TWD | 14.7% | 35.47 TWD | 47.25 TWD | 0.48 | -26.63 | 2.1M | On |
| 12 Jun 2026 | 35.00 TWD | -0.6% | 35.56 TWD | 47.64 TWD | 0.52 | -33.63 | 1.4M | On |
| 5 Jun 2026 | 35.20 TWD | -8.6% | 35.57 TWD | 48.03 TWD | 0.75 | -35.58 | 2.2M | On |
| 29 May 2026 | 38.50 TWD | -2.5% | 35.46 TWD | 48.47 TWD | 0.86 | -30.16 | 1.3M | On |
| 22 May 2026 | 39.50 TWD | -4.6% | 35.23 TWD | 48.79 TWD | 0.95 | -25.26 | 1.2M | On |
| 15 May 2026 | 41.40 TWD | 5.6% | 35.04 TWD | 49.08 TWD | 1.08 | -20.51 | 1.1M | On |
How to use this report
This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.