Healthcare ยท Biotechnology ยท Completed evidence
IDYA relative to DNLI
Ideaya Biosciences Inc is the relatively depressed leg. Denali Therapeutics Inc is the relatively extended leg.
Specific pair strategy
What is the play in IDYA / DNLI?
This is a relative trade. The result depends on which security performs better, not on whether the whole market rises or falls.
Convergence condition active
Long IDYA / short DNLI
Treat the two legs as one relative trade. The idea works when IDYA outperforms DNLI, not simply when IDYA rises or DNLI falls.
This is the relatively depressed leg. The case needs it to recover or at least hold up better than the other leg.
This is the relatively extended leg. The case needs it to lag or weaken relative to the long leg.
A favourable relative move means IDYA rises more than DNLI, falls less than DNLI, or rises while DNLI falls. If DNLI outperforms IDYA, the pair moves against the case.
The research trigger is active because the completed daily gap is narrowing while IDYA improves relative to DNLI. For a fresh position, require the next completed daily update to continue that move toward normal.
Maintain the case only while IDYA continues to gain on DNLI, relationship quality remains usable and the wider evidence does not reverse.
The case fails if the completed gap widens again while IDYA weakens relative to DNLI, or if the publication moves into a relationship-break state.
The cleaner confirmation is a narrowing spread led by weakness in the extended leg rather than strength in both securities.
Evidence now
- DNLI Market Dynamics is weakening.
What would invalidate it?
A fresh strengthening in the extended leg can prolong the separation and increase short-side risk.
Possible setup paths
How the relative-value idea could be expressed
These are research structures, not recommendations or position-size instructions. The current course above determines whether any structure is ready to study now.
Long IDYA / short DNLI
Treat both legs as one relative position. The setup looks for IDYA to outperform DNLI; IDYA can rise faster, fall less, or rise while DNLI falls. The pair loses ground when DNLI outperforms IDYA.
When it becomes relevantThis is the clearest expression to study now because both the weekly evidence and completed daily timing agree. Look for IDYA to keep gaining relative to DNLI while relationship quality and evidence alignment hold.Principal riskRequires a live review of both legs, borrow availability and cost, event dates, liquidity and the research normalisation.Study IDYA alone if its own evidence confirms
This simpler expression focuses on recovery in IDYA. It avoids short-borrow mechanics, but it no longer isolates relative value: the result is exposed to the broad market, the sector and IDYA-specific news.
When it becomes relevantA stronger case needs improving IDYA price structure and supporting evidence, not just a wide relationship gap.Principal riskCarries full single-security and broad-market direction risk.Study DNLI alone if its support continues to weaken
This expression focuses on weakness in DNLI. It may fit a leader-rollover case, but it also abandons the relative hedge and adds direct market direction, squeeze and company-event risk.
When it becomes relevantWeakening in DNLI must be visible in its own completed evidence; relative extension alone is not enough.Principal riskShort selling can involve unlimited loss, borrow fees, recalls and forced close-outs.Any practical expression needs an independent review of suitability, portfolio risk, liquidity, current news and earnings, borrow availability and cost, transaction costs and tax.
Relationship gap ยท technical name: standardised residual
How far apart are they compared with normal?
Zero is the pair's historical centre. The outer guides show increasingly unusual departures from it.
This is the relationship gap after allowing for the pair's usual co-movement. Zero is its historical centre; the distance is measured in standard deviations, so different pairs can be compared on the same scale.
The latest gap is 0.88 standard deviations from normal. IDYA is the relatively depressed leg and DNLI is the relatively extended leg. That is unusual separation, not proof that either security is cheap or expensive.
A move toward zero means convergence. A move farther from zero means the separation is extending and raises the risk that the old relationship is changing.
Common-base price paths
Which security created the gap?
Both paths begin at 100 so their relative movement is visible without mixing different share prices.
Both securities are reset to 100 at the first date. This removes the distraction of different share prices and shows how their completed weekly price paths diverged. It is not a valuation chart.
Since the common starting point, DNLI is +6.0% and IDYA is +28.3%. The chart shows which price path contributed to the separation; the fitted relationship measure is more precise than the raw visual distance.
For convergence, watch for IDYA to catch up, DNLI to lose ground, or both. The relationship can close even if both securities rise or both fall.
DNLIIDYA
Completed daily timing
Is the gap closing yet?
The daily relationship adds timing context inside the slower weekly case. It does not replace the weekly validity checks.
This applies the same relationship to completed daily bars. It is the timing layer inside the weekly case, not a separate trading signal.
Gap narrowing: The completed daily gap is narrowing. That supports the weekly convergence case, although it still needs to persist.
Further movement toward zero would strengthen confirmation; a turn away from zero would weaken it.
IDYA ยท Ideaya Biosciences Inc
80/100 evidence score- Market Dynamics
- 0.724 ยท change -0.398
- Trend
- Positive
- Stage
- Stage 2 ยท Advancing
- Smart Money
- Neutral
- News sentiment
- Neutral
- Options
- Bullish
DNLI ยท Denali Therapeutics Inc
84/100 evidence score- Market Dynamics
- 0.469 ยท change -0.808
- Trend
- Positive
- Stage
- Stage 2 ยท Advancing
- Smart Money
- Neutral
- Short interest
- Squeeze
- Options
- Volatility
Relationship diagnostics
Why this pair is on the map
How closely completed weekly returns moved together across the measurement window.
How consistent the fitted relationship remained across earlier and later parts of the sample.
An observed mean-reversion clock, not a deadline or a forecast.
How often the residual crossed its historical centre; repeated crossings matter more than a single fit.
The latest residual's location inside its own completed history.
Stored price, volume and size context only. It does not include a live short locate or cost.
1 of 1 non-overlapping historical separations resolved after the relationship was fitted on earlier data.
Median time to return near the earlier fitted centre among the held-out cases that resolved.
The largest further move recorded after a measured held-out separation, before resolution or the observation window ended.
State history
What changed and when
Relationship retired
Removed from the current map because the relationship no longer passed the publication checks.
Daily timing changed
Completed daily timing changed to gap narrowing through 2026-08-20.
Daily timing changed
Completed daily timing changed to gap stable through 2026-08-19.
Daily timing changed
Completed daily timing changed to gap narrowing through 2026-08-17.
Relationship discovered
Published as Leader rollover after the completed 2026-08-14 observation.
Same-industry map