Weekly structural research · NASDAQ · Healthcare

IOVA Stage Analysis

Iovance Biotherapeutics Inc

Week ending 9 Oct 2026Close USD 14.62Tenure EstablishedBenchmark QQQ

Screen this regime Supporting research Report data ↗

Executive diagnosis

What the Activity Line geometry says now

Structure, not prediction

Upward Expansion · Established expansion

The weekly architecture is expanding upward.

Trend and Activity show sustained positive alignment with constructive price acceptance. Directional energy remains positive; cooling within this regime can indicate that it is maturing.

The Trend gate is up within the current regime.
Fast Activity versus Slow Activity: improving.
Activity structure: wide and expanding.

Direction 90−100 bearish to +100 bullish

Energy 91/100directional strength

Maturity 58/100lifecycle context

Confidence 75/100evidence agreement

Trend gate Upstructural direction

Activity structure Wideexpanding separation

Price acceptance +100.0%position within the Activity structure

Fair Value context +136.8%USD 6.17 · improving

Trend Architecture map · Historical context

Weekly close, Activity, Trend and Fair Value

Follow price and Trend first, then add Activity Lines to inspect the structure. Subtle bands show the regime recognized at each completed observation; the dashed line marks current Fair Value, not a historical forecast.

CloseTrendCurrent Fair Value

Background stage key

BalanceDirection is contained.
Rotation UpStructure is turning higher.
Upward ExpansionUptrend is established.
DecelerationUptrend is losing energy.
Rotation DownStructure is turning lower.
Downward ExpansionDowntrend is established.

View chart values · 156 observations

Week	Close	Trend	Relative Strength	Volume	Regime	Direction	Energy
2026-10-09	14.62	5.88	191.82	77050682	Upward Expansion	90	91
2026-10-02	14.22	5.53	198.03	147631014	Upward Expansion	96	89
2026-09-25	11.00	5.22	143.28	69665791	Upward Expansion	88	90
2026-09-18	10.25	4.99	142.81	98906557	Upward Expansion	88	91
2026-09-11	8.60	4.74	113.15	44441151	Upward Expansion	74	90
2026-09-04	8.79	4.54	122.80	53996984	Upward Expansion	82	93
2026-08-28	8.01	4.33	109.54	52872019	Upward Expansion	81	92
2026-08-21	8.29	4.15	123.63	121179980	Upward Expansion	91	91
2026-08-14	6.98	3.96	88.38	74332863	Upward Expansion	88	82
2026-08-07	6.34	3.81	76.43	143700799	Upward Expansion	85	69
2026-07-31	4.07	3.68	21.42	71612325	Upward Expansion	56	39
2026-07-24	4.99	3.62	50.31	70039863	Upward Expansion	70	62
2026-07-17	5.00	3.55	49.24	122064045	Upward Expansion	74	54
2026-07-10	4.23	3.47	22.57	58400814	Upward Expansion	55	34
2026-07-03	4.31	3.40	28.42	62850323	Upward Expansion	58	36
2026-06-26	4.25	3.33	29.25	77940810	Upward Expansion	59	44
2026-06-19	3.91	3.27	14.95	56586011	Upward Expansion	54	51
2026-06-12	4.08	3.22	23.93	53919501	Upward Expansion	57	59
2026-06-05	4.23	3.16	32.23	79137567	Upward Expansion	61	50
2026-05-29	4.10	3.10	23.50	53945921	Deceleration	57	33
2026-05-22	4.11	3.03	28.58	61387643	Deceleration	57	27
2026-05-15	3.45	2.97	10.30	68387807	Deceleration	34	16
2026-05-08	3.62	2.92	16.21	119673390	Deceleration	37	20
2026-05-01	3.40	2.87	15.91	56807008	Deceleration	37	21
2026-04-24	3.44	2.84	17.97	69949997	Deceleration	39	22
2026-04-17	3.86	2.79	33.95	65803081	Deceleration	44	26
2026-04-10	3.70	2.73	35.77	106470384	Deceleration	41	25
2026-04-03	3.43	2.68	30.77	37981073	Upward Expansion	54	36
2026-03-27	3.51	2.65	38.40	47405600	Upward Expansion	62	62
2026-03-20	3.69	2.61	39.97	72895490	Upward Expansion	65	79
2026-03-13	3.96	2.58	46.60	113960463	Upward Expansion	66	81
2026-03-06	5.13	2.53	87.33	119930508	Upward Expansion	96	93
2026-02-27	3.86	2.43	39.73	169351283	Upward Expansion	89	77
2026-02-20	2.87	2.39	2.76	31582804	Upward Expansion	66	45
2026-02-13	2.57	2.40	-9.34	34627126	Balance	50	27
2026-02-06	2.53	2.39	-14.03	56020477	Balance	46	22
2026-01-30	2.55	2.37	-17.29	64724455	Balance	48	23
2026-01-23	2.64	2.34	-16.80	51845837	Balance	54	26
2026-01-16	2.36	2.31	-27.53	67474617	Balance	46	35
2026-01-09	2.45	2.30	-27.43	57306228	Balance	48	47
2026-01-02	2.52	2.29	-26.03	44207104	Balance	48	44
2025-12-26	2.85	2.27	-20.73	42040901	Balance	65	44
2025-12-19	2.48	2.24	-32.33	87121428	Balance	42	21
2025-12-12	2.20	2.21	-41.58	52122284	Balance	25	10
2025-12-05	2.20	2.19	-44.64	42786751	Balance	38	21
2025-11-28	2.47	2.18	-39.73	35712580	Balance	44	26
2025-11-21	2.24	2.21	-44.94	55384534	Balance	29	13
2025-11-14	2.47	2.26	-43.25	93128496	Balance	13	7
2025-11-07	2.30	2.28	-48.95	197906094	Balance	-29	16
2025-10-31	1.97	2.31	-59.41	67729255	Balance	-46	32
2025-10-24	2.25	2.34	-54.98	66616408	Balance	-33	15
2025-10-17	2.18	2.39	-57.25	53699481	Balance	-35	18
2025-10-10	2.10	2.43	-59.41	68040446	Balance	-47	24
2025-10-03	2.34	2.48	-57.31	40818382	Balance	-33	19
2025-09-26	2.11	2.53	-62.45	43648314	Balance	-37	21
2025-09-19	2.05	2.60	-64.85	58936237	Balance	-38	21
2025-09-12	2.27	2.72	-61.58	48764607	Balance	-26	13
2025-09-05	2.49	2.83	-58.51	38720090	Balance	-20	10
2025-08-29	2.23	2.94	-63.69	48002712	Balance	-17	11
2025-08-22	2.69	3.06	-57.88	77680090	Balance	-5	9
2025-08-15	2.55	3.18	-61.77	67731623	Downward Expansion	-10	17
2025-08-08	2.11	3.29	-69.13	104154412	Downward Expansion	-21	22
2025-08-01	2.68	3.44	-60.50	87222110	Downward Expansion	-26	22
2025-07-25	3.13	3.60	-55.77	250534527	Downward Expansion	-22	17
2025-07-18	2.23	3.74	-68.89	121014714	Downward Expansion	-51	49
2025-07-11	1.87	3.91	-74.09	60767855	Downward Expansion	-63	61
2025-07-04	1.75	4.11	-76.34	28009395	Downward Expansion	-69	63
2025-06-27	1.69	4.36	-77.19	59684652	Downward Expansion	-74	64
2025-06-20	1.98	4.61	-72.71	40096170	Downward Expansion	-67	64
2025-06-13	2.24	4.83	-69.68	78820663	Downward Expansion	-66	74
2025-06-06	2.05	5.03	-72.89	52118656	Downward Expansion	-67	87
2025-05-30	1.75	5.31	-76.78	45670753	Downward Expansion	-71	89
2025-05-23	1.78	5.63	-76.44	57093181	Downward Expansion	-76	72
2025-05-16	1.66	5.92	-79.05	112838350	Downward Expansion	-85	72
2025-05-09	1.75	6.21	-76.96	168623796	Downward Expansion	-89	71
2025-05-02	3.50	6.47	-55.19	40463364	Downward Expansion	-64	62
2025-04-25	3.51	6.71	-54.84	46173227	Downward Expansion	-67	65
2025-04-18	3.06	6.91	-59.05	34249750	Downward Expansion	-74	69
2025-04-11	3.30	7.15	-57.83	62498005	Downward Expansion	-70	78
2025-04-04	3.00	7.38	-59.73	52038059	Downward Expansion	-80	90
2025-03-28	3.56	7.61	-58.02	39225153	Downward Expansion	-70	87
2025-03-21	3.54	7.88	-60.33	39386619	Downward Expansion	-76	90
2025-03-14	3.59	8.16	-60.75	42568702	Downward Expansion	-82	89
2025-03-07	3.75	8.39	-60.98	68513456	Downward Expansion	-86	86
2025-02-28	4.24	8.60	-58.51	87089935	Downward Expansion	-86	87
2025-02-21	5.78	8.72	-46.81	30181900	Downward Expansion	-66	81
2025-02-14	5.57	8.83	-51.05	42180502	Downward Expansion	-73	86
2025-02-07	5.69	8.91	-49.05	32436344	Downward Expansion	-72	84
2025-01-31	5.85	9.01	-48.03	38617191	Downward Expansion	-72	80
2025-01-24	6.25	9.06	-45.60	33742527	Downward Expansion	-69	77
2025-01-17	5.91	9.12	-48.07	57553428	Downward Expansion	-78	79
2025-01-10	6.40	9.19	-42.52	40285243	Downward Expansion	-74	73
2025-01-03	7.65	9.25	-33.36	32405604	Rotation Down	-60	66
2024-12-27	7.37	9.25	-36.66	24412721	Rotation Down	-41	57
2024-12-20	7.38	9.30	-36.31	37382023	Rotation Down	-43	52
2024-12-13	7.83	9.39	-34.30	25229010	Balance	-30	47
2024-12-06	9.03	9.47	-23.94	20412041	Balance	-14	29
2024-11-29	9.32	9.54	-18.87	23955903	Balance	-10	20
2024-11-22	8.55	9.68	-24.86	44639021	Balance	-17	22
2024-11-15	8.18	9.78	-26.65	51726802	Balance	-1	2
2024-11-08	10.58	9.89	-8.07	57235293	Balance	48	35
2024-11-01	11.19	9.95	3.40	22701998	Balance	28	23
2024-10-25	10.67	10.02	-2.01	24249291	Balance	12	9
2024-10-18	10.24	10.16	-4.85	28575245	Balance	2	5
2024-10-11	9.74	10.32	-8.38	19442743	Balance	-18	12
2024-10-04	10.46	10.46	0.48	19951023	Balance	-21	12
2024-09-27	9.61	10.64	-6.71	19875750	Balance	-23	15
2024-09-20	10.15	10.87	0.19	26705748	Balance	-5	12
2024-09-13	10.34	11.06	4.29	39461776	Balance	0	21
2024-09-06	10.01	11.02	7.70	20812001	Downward Expansion	0	25
2024-08-30	11.66	10.99	18.87	23738979	Downward Expansion	12	32
2024-08-23	11.87	10.87	20.98	34637972	Downward Expansion	11	23
2024-08-16	10.50	10.73	8.93	36510156	Downward Expansion	-21	21
2024-08-09	9.92	10.64	9.06	54749915	Downward Expansion	-40	24
2024-08-02	7.79	10.61	-13.83	35825662	Downward Expansion	-53	36
2024-07-26	9.25	10.63	-1.03	27077555	Downward Expansion	-48	37
2024-07-19	7.96	10.59	-16.94	29820715	Downward Expansion	-64	51
2024-07-12	8.73	10.60	-12.83	33814982	Rotation Down	-64	56
2024-07-05	7.28	10.57	-27.71	25087845	Rotation Down	-48	71
2024-06-28	8.02	10.54	-17.93	45749314	Rotation Down	-41	71
2024-06-21	8.01	10.48	-18.28	31610852	Rotation Down	-45	73
2024-06-14	8.16	10.41	-17.02	41349979	Rotation Down	-37	68
2024-06-07	7.78	10.31	-18.51	40242075	Rotation Down	-43	68
2024-05-31	8.88	10.18	-4.95	27188646	Deceleration	-36	50
2024-05-24	10.01	10.02	4.93	26121466	Deceleration	-5	18
2024-05-17	10.24	9.81	8.82	32778245	Deceleration	1	11
2024-05-10	10.96	9.58	19.15	37044578	Deceleration	22	18
2024-05-03	13.63	9.33	50.58	23201911	Deceleration	37	25
2024-04-26	11.64	9.01	31.14	15120632	Deceleration	31	26
2024-04-19	11.31	8.78	33.62	23886893	Deceleration	37	24
2024-04-12	12.36	8.56	39.35	22780306	Deceleration	45	39
2024-04-05	13.53	8.32	53.30	21457058	Upward Expansion	59	51
2024-03-29	14.82	8.07	68.50	19974969	Upward Expansion	64	62
2024-03-22	15.02	7.78	72.25	28778048	Upward Expansion	66	84
2024-03-15	13.91	7.49	66.90	46566987	Upward Expansion	68	88
2024-03-08	15.70	7.23	88.22	47029709	Upward Expansion	78	91
2024-03-01	16.79	6.94	101.18	67599639	Upward Expansion	92	96
2024-02-23	15.77	6.62	95.38	170637844	Upward Expansion	92	86
2024-02-16	9.15	6.33	16.45	43025942	Upward Expansion	66	45
2024-02-09	9.18	6.28	14.69	26686725	Upward Expansion	69	43
2024-02-02	7.90	6.24	0.16	25688379	Upward Expansion	48	37
2024-01-26	7.59	6.22	-3.38	28740414	Upward Expansion	61	47
2024-01-19	7.78	6.20	-1.35	26163989	Rotation Up	64	55
2024-01-12	9.01	6.21	17.03	41181298	Rotation Up	50	69
2024-01-05	8.47	6.18	13.48	25551706	Rotation Up	48	75
2023-12-29	8.13	6.16	5.26	66748452	Rotation Up	40	71
2023-12-22	8.34	6.18	7.86	37441115	Rotation Up	50	74
2023-12-15	7.78	6.15	1.31	47631092	Rotation Up	49	53
2023-12-08	6.40	6.14	-14.26	31409297	Downward Expansion	13	33
2023-12-01	6.26	6.18	-16.37	33857134	Downward Expansion	-2	22
2023-11-24	5.79	6.20	-23.14	38295537	Downward Expansion	-25	26
2023-11-17	5.05	6.19	-32.81	33998556	Downward Expansion	-48	41
2023-11-10	3.97	6.21	-46.66	35122925	Downward Expansion	-64	59
2023-11-03	4.21	6.27	-42.94	27182494	Downward Expansion	-67	77
2023-10-27	3.50	6.32	-50.55	27324562	Downward Expansion	-73	88
2023-10-20	3.33	6.41	-55.22	30708880	Downward Expansion	-82	92

Price vs TrendAbove+148.5%

Trend directionRising+60.0%

Price vs current Fair ValuePremium+136.8%

Fair Value directionClosing upward+165.7%

Relative Strength vs benchmarkLeading+191.8%

Relative strength directionImproving+169.2%

Price momentumPositive+295.1%

Volume balanceDemand-led3.80×

Beyond the current label

Is the structure strengthening or losing force?

Direction and energy measure different things

Direction shows the upward or downward lean. Energy shows the force behind the structural move: high energy can accompany a strong decline as well as an advance.

Direction

90 / ±100

+16.2 points since 2026-09-11

Energy

91 /100

+1.9 points since 2026-09-11

Recent change compares the latest reading with four observations earlier. Missing readings remain unavailable. Use the chart values above to inspect individual observations.

IOVA Directional State ↗ IOVA Momentum Intelligence ↗

Comparative structural evidence

Why this architecture regime won

Every regime is evaluated

Balance1

Rotation Up89

Upward Expansion98

Deceleration41

Rotation Down8

Downward Expansion20

The winning regime is the state most consistent with the complete SM evidence set. Direction, energy, maturity and confidence describe different aspects of the current structure, while contradictory evidence remains visible rather than being averaged into false certainty.

Time spent in each state

The context behind today’s regime

2023-10-20 to 2026-10-09 · 156 classified observations out of 156 shown.

Balance 26%Rotation Up 4%Upward Expansion 24%Deceleration 10%Rotation Down 6%Downward Expansion 31%

Recent Trend Architecture ledger

Regime	Recognized	Last observation	Tenure	Move inside regime
Upward Expansion	2026-06-05	2026-10-09	Established	+245.6%
Deceleration	2026-04-10	2026-05-29	Developing	+10.8%
Upward Expansion	2026-02-20	2026-04-03	Developing	+19.5%
Balance	2025-08-22	2026-02-13	Established	-4.5%
Downward Expansion	2025-01-10	2025-08-15	Extended	-60.2%
Rotation Down	2024-12-20	2025-01-03	New	+3.7%
Balance	2024-09-13	2024-12-13	Established	-24.3%
Downward Expansion	2024-07-19	2024-09-06	Developing	+25.8%
Rotation Down	2024-06-07	2024-07-12	Developing	+12.2%
Deceleration	2024-04-12	2024-05-31	Developing	-28.2%
Upward Expansion	2024-01-26	2024-04-05	Developing	+78.3%
Rotation Up	2023-12-15	2024-01-19	Developing	+0.0%
Downward Expansion	2023-09-29	2023-12-08	Developing	+40.7%
Rotation Down	2023-09-01	2023-09-22	New	-20.8%

Classic Stage Analysis comparison

Stage 1 · Basing19

Stage 2 · Advancing100

Stage 3 · Distribution51

Stage 4 · Declining0

Legacy result: Stage 2 · Stage 2C · Late advance. It remains visible while the experimental architecture is validated rather than being silently discarded.

Leadership versus QQQ

Is relative performance confirming the geometry?

Confirmation, not classification

Relative Strength

The security is compared with its market benchmark on the SM scale. Above zero indicates relative leadership; direction shows whether that leadership is improving or weakening.

Confirmation evidence

Leading benchmark

Architecture confirmation: 99/100
Current Relative Strength: 191.82
Relative Strength direction: Improving
Price momentum: +295.1%
Excess performance vs benchmark: +272.2%
Healthcare regime cohort: 84th percentile135 in cohort

Test IOVA trend persistence

Participation and structure

Is demand confirming the architecture?

Volume cannot overrule geometry

Relative volume0.97×

Latest completed volume relative to typical participation.

Up/down volume3.80×

Participation balance between advancing and declining observations.

Accumulation / distribution5 / 0

Recent participation evidence classified by demand and supply.

Activity alignment+100.0%

Current positive alignment across Activity and Trend.

Fast/slow rotationImproving

Current relationship between Fast Activity and Slow Activity.

Structure stability+0.0%

Whether recent Activity evidence is stable or remains in balance.

Weekly volume with architecture context

Bars show completed weekly volume; the dashed line provides typical-volume context. Both measures use the same scale.

Explore IOVA Volume & Price ↗

Decision architecture

References that would change the structural read

Evidence levels, not orders

Fast Activity USD 12.80rising

Slow Activity USD 7.36rising

Trend Reference USD 5.88+148.5% close margin

Current Fair Value USD 6.17+136.8% close margin

Structural low USD 3.27shock / repair context

What changes the read?

Sustained fan recompression, a fast-line rollover or repeated closes inside/below the fan move the read toward Deceleration or Rotation Down.

Range context +12.3%

Annualized volatility +90.4%

From structural high -4.4%

From structural low +730.7%

Point-in-time evidence

What followed this architecture in this market?

Descriptive history, never a forecast

Historical comparisons use only the structural read that would have been available at each completed observation. Independent observations are used where possible, with benchmark comparison beginning after each recognized state.

Outcome horizon	Samples	Median move	Positive periods	Directional follow-through	Median excess vs QQQ	Regime survived	Read
Near term	11	+1.9%-24.7% to +107.8%	+54.5%	+54.5%	-2.1%	+72.7%	Usable descriptive sample
Intermediate	4	+48.3%-35.1% to +107.8%	+75.0%	+75.0%	+38.4%	+25.0%	Too little matched history
Extended	3	+21.9%-4.2% to +188.9%	+66.7%	+66.7%	+12.3%	+33.3%	Too little matched history
Full cycle	1	+0.5%+0.5% to +0.5%	+100.0%	+100.0%	-30.6%	+0.0%	Too little matched history

Evidence framework

What the analysis measures and where its limits lie

Trend Architecture

Trend Architecture brings Price, Fast Activity, Slow Activity and Trend into one structural read. It identifies balance, rotation, expansion, deceleration and contraction while requiring persistent evidence for confirmed regime changes.

Evidence roles

Trend, Activity, relative strength, volume and Fair Value each have a defined role in the SM evidence framework. No single reading is treated as sufficient on its own, and conflicting evidence remains visible.

Fair Value and RS

Current Fair Value provides a long-term price anchor and shows whether price is trading above, below or repairing toward that reference. Relative Strength compares the security with its benchmark and shows whether leadership is improving or weakening.

Known limitations

Weekly structure recognizes conditions after they develop. Event gaps can bypass smooth transitions, sideways markets can rotate repeatedly, and historical samples for a particular regime can be thin.

Independent market research for education. Not investment advice, a recommendation, a forecast, a target, or an execution instruction. Historical regime behaviour does not establish what happens next.

IOVA Stage Analysis

What the Activity Line geometry says now

The weekly architecture is expanding upward.

Weekly close, Activity, Trend and Fair Value

Is the structure strengthening or losing force?

Direction

Energy

Why this architecture regime won

The context behind today’s regime

Is relative performance confirming the geometry?

Relative Strength

Leading benchmark

Is demand confirming the architecture?

Weekly volume with architecture context

References that would change the structural read

What followed this architecture in this market?

What the analysis measures and where its limits lie

Trend Architecture

Evidence roles

Fair Value and RS

Known limitations

Send a message

Evidence context

What the Activity Line geometry says now

The weekly architecture is expanding upward.

Weekly close, Activity, Trend and Fair Value

Is the structure strengthening or losing force?

Direction

Energy

Why this architecture regime won

The context behind today’s regime

Is relative performance confirming the geometry?

Relative Strength ?

Leading benchmark

Is demand confirming the architecture?

Weekly volume with architecture context

References that would change the structural read

What followed this architecture in this market?

Test the structure from another angle

Trend Persistence ↗

Directional State ↗

Momentum Intelligence ↗

Volume & Price ↗

Similar Charts ↗

RMI Reversal Map ↗

What the analysis measures and where its limits lie

Trend Architecture

Evidence roles

Fair Value and RS

Known limitations

Relative Strength

Trend Persistence

Directional State

Momentum Intelligence

Volume & Price

Similar Charts

RMI Reversal Map