Sharemaestro · Weekly directional research
Trend Persistence
Find the direction. Test its staying power.
Follow the Core Trend, the agreement behind it and the room remaining before its direction changes. Explore durable trends, fresh turns and signs of internal tension across stocks and ETFs.
The shape of your selection
Direction is only half the picture
879 matching securities, with equal weight. Agreement shows whether faster and slower Trend views support the Core Trend.
All Trend views agree
27.8% of all matchesSome Trend disagreement
23.4% of all matchesAll Trend views agree
25.7% of all matchesSome Trend disagreement
23.1% of all matchesThe four cells separate positive and negative directions by full alignment. 0 neutral readings sit at the boundary and are shown separately above.
Fresh direction changes ↗30
Core Trend changed at the latest completed observation.
Faster Trend disagreement ↗266The responsive view is opposing the established direction.
Near the boundary ↗28A small margin relative to recent weekly variability.
Frequent direction changes ↗385Repeated flips suggest a less stable directional path.
Research lenses can overlap. Counts reflect the current selection.
Research universe
Weekly persistence screener
Ranked for structural coherence and durability. Research priority is not an expected return or probability.
| Market | Current weekly state | Core momentum | Trend agreement | Persistence | Boundary margin | Volatility | Turnover |
|---|---|---|---|---|---|---|---|
| ADPTAdaptive Biotechnologies Corp · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +114.1% |
|
Extendeddirectional lifecycle | +114.1%13.36 | +58.7%annualised | Lowrecent direction changes |
| AMLXAmylyx Pharmaceuticals Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +143.5% |
|
Extendeddirectional lifecycle | +143.5%13.31 | +95.2%annualised | Lowrecent direction changes |
| AMRXAmneal Pharmaceuticals, Inc. Class A Common Stock · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +90.7% |
|
Extendeddirectional lifecycle | +90.7%9.81 | +39.7%annualised | Lowrecent direction changes |
| ARAYAccuray Incorporated · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -86.0% |
|
Maturedirectional lifecycle | -86.0%1.67 | +85.3%annualised | Lowrecent direction changes |
| AUPHAurinia Pharmaceuticals Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +30.0% |
|
Extendeddirectional lifecycle | +30.0%13.00 | +28.1%annualised | Lowrecent direction changes |
| AVAHAveanna Healthcare Holdings Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +68.8% |
|
Maturedirectional lifecycle | +68.8%8.10 | +49.5%annualised | Lowrecent direction changes |
| BDMDBaird Medical Investment Holdings Limited · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -60.2% |
|
Maturedirectional lifecycle | -60.2%2.64 | +47.4%annualised | Lowrecent direction changes |
| BLTEBelite Bio Inc ADR · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +143.5% |
|
Extendeddirectional lifecycle | +143.5%70.20 | +46.9%annualised | Lowrecent direction changes |
| CAHCardinal Health Inc · NYSE | Positive across all Trend viewsHealthcare · weekly chart | +51.9% |
|
Extendeddirectional lifecycle | +51.9%148.39 | +28.1%annualised | Lowrecent direction changes |
| CRONCronos Group Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +27.9% |
|
Maturedirectional lifecycle | +27.9%2.62 | +24.4%annualised | Lowrecent direction changes |
| CTSOCytosorbents Crp · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -69.5% |
|
Maturedirectional lifecycle | -69.5%18.82 | +58.9%annualised | Lowrecent direction changes |
| DFTXDefinium Therapeutics, Inc. · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +329.3% |
|
Maturedirectional lifecycle | +329.3%9.04 | +92.4%annualised | Lowrecent direction changes |
| DGXQuest Diagnostics Incorporated · NYSE | Positive across all Trend viewsHealthcare · weekly chart | +36.0% |
|
Extendeddirectional lifecycle | +36.0%181.19 | +22.1%annualised | Lowrecent direction changes |
| DNTHDianthus Therapeutics Inc. · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +163.4% |
|
Maturedirectional lifecycle | +163.4%36.75 | +41.2%annualised | Lowrecent direction changes |
| DRMADermata Therapeutics Inc · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -78.6% |
|
Extendeddirectional lifecycle | -78.6%5.43 | +67.0%annualised | Lowrecent direction changes |
| DRTSAlpha Tau Medical Ltd · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +272.6% |
|
Maturedirectional lifecycle | +272.6%4.09 | +55.6%annualised | Lowrecent direction changes |
| EXELExelixis Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +45.5% |
|
Extendeddirectional lifecycle | +45.5%40.10 | +26.6%annualised | Lowrecent direction changes |
| GHGuardant Health Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +203.3% |
|
Extendeddirectional lifecycle | +203.3%59.15 | +61.5%annualised | Lowrecent direction changes |
| GHRSGH Research PLC · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +112.0% |
|
Maturedirectional lifecycle | +112.0%13.33 | +52.8%annualised | Lowrecent direction changes |
| GILDGilead Sciences Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +34.1% |
|
Extendeddirectional lifecycle | +34.1%111.97 | +21.9%annualised | Lowrecent direction changes |
| GRDNGuardian Pharmacy Services, Inc. · NYSE | Positive across all Trend viewsHealthcare · weekly chart | +76.9% |
|
Maturedirectional lifecycle | +76.9%25.43 | +37.0%annualised | Lowrecent direction changes |
| ICCCImmuCell Corporation · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +66.9% |
|
Maturedirectional lifecycle | +66.9%5.96 | +39.3%annualised | Lowrecent direction changes |
| IMMXImmix Biopharma Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +470.8% |
|
Maturedirectional lifecycle | +470.8%2.19 | +70.5%annualised | Lowrecent direction changes |
| IMNNImunon Inc · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -72.7% |
|
Maturedirectional lifecycle | -72.7%4.98 | +53.4%annualised | Lowrecent direction changes |
| INBXInhibrx Biosciences, Inc. · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +296.2% |
|
Maturedirectional lifecycle | +296.2%27.60 | +85.7%annualised | Lowrecent direction changes |
| INCYIncyte Corporation · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +44.8% |
|
Extendeddirectional lifecycle | +44.8%86.53 | +31.7%annualised | Lowrecent direction changes |
| IRDOpus Genetics, Inc. · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +240.8% |
|
Maturedirectional lifecycle | +240.8%1.52 | +79.2%annualised | Lowrecent direction changes |
| JAZZJazz Pharmaceuticals PLC · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +87.6% |
|
Maturedirectional lifecycle | +87.6%128.30 | +24.4%annualised | Lowrecent direction changes |
| JNJJohnson & Johnson · NYSE | Positive across all Trend viewsHealthcare · weekly chart | +55.9% |
|
Extendeddirectional lifecycle | +55.9%173.16 | +24.2%annualised | Lowrecent direction changes |
| KNSAKiniksa Pharmaceuticals Ltd · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +118.1% |
|
Extendeddirectional lifecycle | +118.1%35.42 | +52.0%annualised | Lowrecent direction changes |
| LGNDLigand Pharmaceuticals Incorporated · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +70.3% |
|
Extendeddirectional lifecycle | +70.3%166.51 | +32.3%annualised | Lowrecent direction changes |
| MBIOMustang Bio Inc · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -67.7% |
|
Extendeddirectional lifecycle | -67.7%1.67 | +54.6%annualised | Lowrecent direction changes |
| MDMednax Inc · NYSE | Positive across all Trend viewsHealthcare · weekly chart | +59.4% |
|
Extendeddirectional lifecycle | +59.4%16.27 | +25.0%annualised | Lowrecent direction changes |
| MREOMereo BioPharma Group PLC ADR · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -82.6% |
|
Extendeddirectional lifecycle | -82.6%1.74 | +70.3%annualised | Lowrecent direction changes |
| NTRANatera Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +104.0% |
|
Extendeddirectional lifecycle | +104.0%181.11 | +50.2%annualised | Lowrecent direction changes |
| NVNOenVVeno Medical Corp · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -72.5% |
|
Extendeddirectional lifecycle | -72.5%32.67 | +54.9%annualised | Lowrecent direction changes |
| OVIDOvid Therapeutics Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +122.3% |
|
Maturedirectional lifecycle | +122.3%1.21 | +61.3%annualised | Lowrecent direction changes |
| PAVMPAVmed Inc · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -70.0% |
|
Extendeddirectional lifecycle | -70.0%13.20 | +66.3%annualised | Lowrecent direction changes |
| PBYIPuma Biotechnology Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +117.2% |
|
Maturedirectional lifecycle | +117.2%4.42 | +38.2%annualised | Lowrecent direction changes |
| PGENPrecigen Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +107.5% |
|
Maturedirectional lifecycle | +107.5%3.75 | +72.9%annualised | Lowrecent direction changes |
| PLURPluri Inc. · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -76.5% |
|
Maturedirectional lifecycle | -76.5%4.60 | +75.8%annualised | Lowrecent direction changes |
| PMCBPharmaCyte Biotech Inc · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -53.1% |
|
Extendeddirectional lifecycle | -53.1%0.98 | +44.8%annualised | Lowrecent direction changes |
| PREPrenetics Global Ltd · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +101.6% |
|
Maturedirectional lifecycle | +101.6%12.00 | +61.8%annualised | Lowrecent direction changes |
| PSNLPersonalis Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +168.9% |
|
Maturedirectional lifecycle | +168.9%6.10 | +95.3%annualised | Lowrecent direction changes |
| PTGXProtagonist Therapeutics Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +129.9% |
|
Extendeddirectional lifecycle | +129.9%62.20 | +33.9%annualised | Lowrecent direction changes |
| PVLAPalvella Therapeutics, Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +158.5% |
|
Maturedirectional lifecycle | +158.5%58.24 | +55.8%annualised | Lowrecent direction changes |
| ROIVRoivant Sciences Ltd · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +164.4% |
|
Maturedirectional lifecycle | +164.4%15.04 | +35.5%annualised | Lowrecent direction changes |
| RPRXRoyalty Pharma Plc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +63.6% |
|
Extendeddirectional lifecycle | +63.6%35.69 | +23.9%annualised | Lowrecent direction changes |
| SILOSilo Pharma Inc · NASDAQ | Negative across all Trend viewsHealthcare · weekly chart | -82.1% |
|
Extendeddirectional lifecycle | -82.1%10.26 | +71.9%annualised | Lowrecent direction changes |
| SLSSellas Life Sciences Group Inc · NASDAQ | Positive across all Trend viewsHealthcare · weekly chart | +604.9% |
|
Maturedirectional lifecycle | +604.9%1.63 | +113.5%annualised | Lowrecent direction changes |
Participation beneath the trend
Where direction has broad support
879 matches in identified sectors. Bars show each sector’s direction mix; alignment includes both positive and negative trends.
51%positive54%fully aligned
PositiveNegativeAt boundary
Ordered by positive share. Small groups can move sharply when a few securities change direction. Unclassified securities remain in overall calculations.
Reading the framework
Direction, agreement, durability and sensitivity
Four complementary questions, each with a distinct role in the research.
Direction
The Core Trend sets the primary positive, negative or neutral state.
Agreement
Faster and slower Trend views show whether directional pressure is broad or divided.
Durability
Trend age and recent flips distinguish established direction from frequent reversals.
Boundary
The Direction Boundary is the current price reference separating positive and negative Core Trend.
Core Trend
The primary state describes the established weekly price direction using continuous completed market history.
Sharemaestro context
Faster and slower Trend views, persistence, turnover, boundary distance and volatility show whether that state is broad, established, divided or fragile. They do not rewrite it.
Research priority
The ordering brings the most coherent and durable Trend states forward for research. It is not confidence, expected return or a promise of continuation.
Honest limitations
Trend effects can reverse, gap through boundaries and suffer repeated false turns. Historical outcome panels use only information available at each past observation and show their sample size rather than hiding uncertainty.
Published 20 Sep 2026 · 10:32 BST · tp-1.0.0.