Sharemaestro company-news research for Summit Therapeutics Inc. (SMMT), showing current tone, evidence confidence, direct company coverage, sector and industry context, completed price response and the source headlines used on the page. Scores describe published news evidence. Confidence describes the amount, freshness, source breadth and direct company relevance of that evidence. Price context is shown separately.

MEX Mexico Provisional evidence

Company news sentiment

Latest SMMT news and sentiment

Summit Therapeutics Inc.

Company headlines from the last 30 days, weighted by freshness, relevance, publisher quality and the strength of the wording. Price is shown separately.

30-day score53Neutral is 50
Early balanced news score 19/100 evidence confidence 78% direct company focus 14 current stories across 1 publishers
Latest weekly closeMXN 290.12week of 11 Sep 2026
Main news subjectEarnings80/100 share of current news
News data statusPartial14 duplicate stories removed

Current company news

Early balanced news score

14 company-specific stories are available, but there are not yet enough fresh stories from separate publishers for a firm reading.

Observed headline tone77/100 Published 30-day score53/100

Older, less relevant and less reliable stories count for less. Confidence is shown separately.

Latest source headline Updated HARMONi Data Presented at WCLC 2026 Demonstrate Consistent Overall Survival Results with Ivonescimab Plus Chemotherapy in Western and Asian Patients finance.yahoo.com ยท 15 Sep 2026 10:00

What supports the score

Direct evidence

14 current stories are mapped specifically to SMMT.

What limits the score

Source breadth

Only 1 publisher currently contribute to the measured read.

Too little evidence

The stories agree, but freshness-weighted evidence is only 0.101.

Confidence

Confidence is 19/100, below the threshold for a firm score.

53/100
News scoreEarly balanced news score
19/100
Confidencethin evidence
78%/100
Company news14 company stories
92/100
Story agreement8/100 difference

News history

Daily score and story count over 30 days

Daily weighted evidence
25 Aug: 2 stories27 Aug: 4 stories02 Sep: 1 stories03 Sep: 2 stories04 Sep: 1 stories07 Sep: 1 stories09 Sep: 1 stories13 Sep: 1 stories15 Sep: 1 stories 25 Aug: tone 52, 2 stories27 Aug: tone 54, 4 stories02 Sep: tone 50, 1 stories03 Sep: tone 50, 2 stories04 Sep: tone 70, 1 stories07 Sep: tone 83, 1 stories09 Sep: tone 50, 1 stories13 Sep: tone 50, 1 stories15 Sep: tone 50, 1 stories 95505
19 Aug03 Sep17 Sep
News scoreStory count50 baseline

Confidence

How reliable the score is

Separate from direction

Confidence uses the amount of news, separate publishers, direct company relevance, freshness and agreement. A high or low score is not automatically reliable.

Amount of evidence2
0.101 after freshness weighting
Source breadth20
1 independent publishers
Company relevance78
share tied directly to this company
Freshness36
recency-weighted evidence
Agreement92
how closely stories agree
Publisher mix0
less reliance on one publisher

Price and news history

Weekly price and news-score history

Early company-news score

Company-specific news is present, but the evidence has not yet earned enough independent, fresh information weight for price confirmation to be treated as a firm signal.

26 completed price weeks12 comparable news-score weeks
One scoring method across the chart.Stored company headlines are recalculated at each weekly point with the current 30-day freshness weighting. Old published snapshots are left unchanged.
20 Mar 2026: close 281.0, indexed 100.027 Mar 2026: close 281.0, indexed 100.003 Apr 2026: close 281.0, indexed 100.010 Apr 2026: close 281.0, indexed 100.017 Apr 2026: close 358.640015, indexed 127.624 Apr 2026: close 407.579987, indexed 145.001 May 2026: close 407.579987, indexed 145.008 May 2026: close 407.579987, indexed 145.015 May 2026: close 407.579987, indexed 145.022 May 2026: close 407.579987, indexed 145.029 May 2026: close 290.119995, indexed 103.205 Jun 2026: close 290.119995, indexed 103.212 Jun 2026: close 290.119995, indexed 103.219 Jun 2026: close 290.119995, indexed 103.226 Jun 2026: close 290.119995, indexed 103.203 Jul 2026: close 290.119995, indexed 103.210 Jul 2026: close 290.119995, indexed 103.217 Jul 2026: close 290.119995, indexed 103.224 Jul 2026: close 290.119995, indexed 103.231 Jul 2026: close 290.119995, indexed 103.207 Aug 2026: close 290.119995, indexed 103.214 Aug 2026: close 290.119995, indexed 103.221 Aug 2026: close 290.119995, indexed 103.228 Aug 2026: close 290.119995, indexed 103.204 Sep 2026: close 290.119995, indexed 103.211 Sep 2026: close 290.119995, indexed 103.2 26 Jun 2026: news score 49, close 290.119995, 5 stories4903 Jul 2026: news score 50, close 290.119995, 7 stories10 Jul 2026: news score 50, close 290.119995, 11 stories5017 Jul 2026: news score 50, close 290.119995, 13 stories24 Jul 2026: news score 51, close 290.119995, 23 stories5131 Jul 2026: news score 50, close 290.119995, 22 stories07 Aug 2026: news score 51, close 290.119995, 24 stories5114 Aug 2026: news score 54, close 290.119995, 25 stories21 Aug 2026: news score 52, close 290.119995, 21 stories5228 Aug 2026: news score 52, close 290.119995, 16 stories04 Sep 2026: news score 53, close 290.119995, 16 stories5311 Sep 2026: news score 54, close 290.119995, 14 stories54 Price index 150.5 122.5 94.6 News score 100 50 0
20 Mar16 Jun11 Sep
Weekly close, indexedSentiment score
26-week price+3.2%latest close 290.12
News score change+5first to latest comparable week
One-week response+0.0%Price digesting
Fair-value position-21.4%Below fair value
WeekNews scoreCloseWeekly move
11 Sep 202654MXN 290.119995+0.0%
04 Sep 202653MXN 290.119995+0.0%
28 Aug 202652MXN 290.119995+0.0%
21 Aug 202652MXN 290.119995+0.0%
14 Aug 202654MXN 290.119995+0.0%
07 Aug 202651MXN 290.119995+0.0%
31 Jul 202650MXN 290.119995+0.0%
24 Jul 202651MXN 290.119995+0.0%
Provisional evidence

News subjects

What is shaping the score

Earnings
Earnings708 stories ยท 57%
Regulatory and legal503 stories ยท 21%
Market update502 stories ยท 14%
Analyst action631 stories ยท 7%

Source mix

Where the evidence comes from

0/100 independence
finance.yahoo.com6312 stories ยท 86%
seekingalpha.com502 stories ยท 14%

Recurring subjects

Subjects appearing most often

Current evidence
Clinical Trials14Biotech12Lung Cancer6Fda Approval5Pharma3Oncology3Share Price2Nsclc2Intrinsic Value2Fourth Quarter2

Earlier readings

How the score has changed

34 comparable readings ยท 86 days
Past and present use the same method.Each point recalculates the previous 30 days of stored company headlines with today's scoring rules. The original stored snapshots remain unchanged.
Comparable move+350 to 53 ยท Broadly stable
Observed range49โ€“5750 is the neutral baseline
Evidence depth14stories at latest stored reading ยท +13
Confidence19/100Provisional ยท +19
21 Jun50 neutral15 Sep 18:18
ConstructiveBalanced or withheldCautious

Changes in the stored score

Scores are rebuilt from stored headlines with the current 30-day method. Days with no change are collapsed.

ObservedScoreMoveConfidenceStoriesStatus
15 Sep 18:1853+019/100 (-1)14 (+1)Provisional
13 Sep 23:5953-320/100 (-5)13 (-3)Provisional
09 Sep 23:5956-125/100 (-4)16 (+1)Provisional
07 Sep 23:5957+429/100 (+2)15 (-1)Provisional
04 Sep 23:5953+227/100 (+10)16 (-1)Provisional
03 Sep 23:5951+017/100 (-1)17 (+2)Provisional
02 Sep 23:5951-118/100 (-7)15 (-1)Provisional
27 Aug 23:5952+025/100 (+1)16 (+2)Provisional

Source headlines

The news behind the score

Showing 1-14 of 14

Only company-specific stories enter this score. The latest 30 days are shown newest first, with newer stories weighted more heavily and duplicate coverage combined.

#1Not directional
finance.yahoo.comDirect company coverageStored article

Updated HARMONi Data Presented at WCLC 2026 Demonstrate Consistent Overall Survival Results with Ivonescimab Plus Chemotherapy in Western and Asian Patients

Sustained OS Improvement Seen with Longer Follow-Up in Western Patients, Consistent across Geographic Regions; No New Safety Signals Observed Akeso-Sponsored HARMONi-2 OS Data Also Presented at WCLC 2026; Additional Data from Landmark China-Only Study Included Herein MIAMI, September 15, 2026--(BUSINESS WIRE)--Summit Therapeutics Inc. (Nasdaq: SMMT) announced that updated overall survival (OS) results from the global Phase III HARMONi clinical trial featuring the novel, potential first-in-class investigational bispecific antibody ivonescimab were presented today at the International Associatio

BiotechClinical TrialsFdaFourth QuarterLung CancerOncology
Published
15 Sep 2026 10:00
News subject
Regulatory and legal
Why this score
The headline reports news without a clear direction
Company focus
Company discussed ยท 86%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 1.7d old
Duplicates
1 consolidated
#2Not directional
seekingalpha.comDirect company coverageStored article

Summitโ€™s ivonescimab cuts death risk by 27% versus Keytruda in lung cancer trial

[Human Respiratory System] nopparit/iStock via Getty Images Summit Therapeutics (SMMT [https://seekingalpha.com/symbol/SMMT]) on Sunday said ivonescimab significantly extended survival compared with Merckโ€™s (MRK [https://seekingalpha.com/symbol/MRK]) Keytruda in a late-stage lung cancer trial conducted by its partner Akeso (AKESF [https://seekingalpha.com/symbol/AKESF]) in China. Ivonescimab reduced the risk of death by 27% compared with Keytruda, also known as pembrolizumab, among previously untreated patients with advanced non-small cell lung cancer whose tumors expressed PD-L1. Median overa

Clinical TrialsFda ApprovalLung CancerPharma
Published
13 Sep 2026 17:23
News subject
Regulatory and legal
Why this score
The headline reports news without a clear direction
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 3.4d old
Duplicates
1 consolidated
#3Not directional
finance.yahoo.comDirect company coverageStored article

Summit (SMMT) Says Akeso Reported a HARMONi-2 Overall-Survival Benefit Against Pembrolizumab

Summit Therapeutics Inc. (NASDAQ:SMMT) said partner Akeso reported a statistically significant overall survival benefit for ivonescimab monotherapy over pembrolizumab in a prespecified interim analysis of Phase 3 HARMONi-2. The randomized, double-blind study enrolled 398 patients at 55 hospitals in China with previously untreated, PD-L1-positive advanced non-small cell lung cancer without sensitizing EGFR mutations or ALK translocations. Overall survival was a prespecified secondary endpoint. Earlier analysis showed median progression-free survival of 11.1 months with ivonescimab and 5.8 month

BiotechClinical TrialsEarnings
Published
09 Sep 2026 01:32
News subject
Earnings
Why this score
The headline reports news without a clear direction
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 8.0d old
Duplicates
1 consolidated
#483Tone
finance.yahoo.comDirect company coverageStored article

Summit Therapeutics (SMMT) Soars 28% on Ivonescimab Progress

Summit Therapeutics (NASDAQ:SMMT) has seen its share price surge by 28.19 percent week-on-week, primarily driven by the positive results of an ongoing clinical trial for its bispecific antibody, ivonescimab. In an updated report during the week, the listed biopharmaceutical firm said that its China-based partner, Akeso Inc., saw positive overall survival results from the randomized double-blind Phase 3 Harmoni-2 study evaluating ivonescimab monotherapy in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors have positive PD-L1 expression. It also reporte

BiotechCancer TreatmentClinical TrialsLung CancerShare Price
Published
07 Sep 2026 05:53
News subject
Earnings
Why this score
Large positive market reaction, Positive market reaction
Company focus
Shared story ยท 78%
How it is used
Direct company coverage
Story strength
High ยท 65/100
30-day weight
61.9% of the score ยท 9.8d old
Duplicates
1 consolidated
#570Tone
finance.yahoo.comDirect company coverageStored article

SMMT Stock Soars on NSCLC Drug Survival Data Beating Keytruda in China

Summit Therapeutics SMMT stock climbed 17.3% on Thursday after its Chinese partner Akeso reported positive overall survival (OS) results for ivonescimab in a head-to-head phase III study against Merck's MRK blockbuster oncology drug, Keytruda (pembrolizumab), in certain patients with non-small cell lung cancer (NSCLC). The data provided fresh clinical validation for SMMT's lead oncology candidate and increased investor focus on the drug's potential in the United States and other licensed markets. Summit Therapeutics is developing ivonescimab in collaboration with Akeso. The company acquired an

BiotechClinical TrialsNsclcOncologyRegulation
Published
04 Sep 2026 14:37
News subject
Earnings
Why this score
Positive market reaction, Large positive market reaction
Company focus
Shared story ยท 78%
How it is used
Direct company coverage
Story strength
Medium ยท 50/100
30-day weight
30.7% of the score ยท 12.5d old
Duplicates
1 consolidated
#6Not directional
finance.yahoo.comDirect company coverageStored article

Summit Packs A Punch For Merck's Keytruda โ€” But Not Everyone Is Sold

Summit Therapeutics stock rocketed Thursday after its experimental cancer drug outperformed Merck's blockbuster, Keytruda. Continue Reading

BiotechClinical Trials
Published
03 Sep 2026 17:29
News subject
Market update
Why this score
The headline reports news without a clear direction
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 13.4d old
Duplicates
1 consolidated
#7Not directional
finance.yahoo.comDirect company coverageStored article

Summit Therapeutics Says It Is Beating Merck With Its Cancer Drug

Summit says its ivonescimab is keeping lung-cancer patients alive longer than Keytruda does. The stock is up. Continue Reading

BiotechClinical TrialsLung Cancer
Published
03 Sep 2026 16:00
News subject
Market update
Why this score
The headline reports news without a clear direction
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 13.4d old
Duplicates
1 consolidated
#8Not directional
seekingalpha.comDirect company coverageStored article

Summit Therapeutics in focus as its lung cancer drug shows survival benefit

* Summit Therapeutics (SMMT [https://seekingalpha.com/symbol/SMMT]) said on Wednesday that partner Akeso (AKESF [https://seekingalpha.com/symbol/AKESF]) reported positive overall survival results [https://seekingalpha.com/pr/20639170-ivonescimab-monotherapy-demonstrates-statistically-significant-overall-survival-benefit] for ivonescimab in the Phase III HARMONi-2 study. * Ivonescimab delivered a statistically significant improvement in overall survival benefit compared with pembrolizumab in patients with PD-L1-positive advanced or metastatic non-small cell lung cancer. * The drug had previousl

BiotechClinical TrialsLung Cancer
Published
02 Sep 2026 22:09
News subject
Earnings
Why this score
Positive financial language
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 14.2d old
Duplicates
1 consolidated
#9Not directional
finance.yahoo.comDirect company coverageStored article

SMMT Rises on Akeso's Win in Phase III Biliary Tract Cancer Study

Shares of Summit Therapeutics SMMT rose 6.5% on Wednesday after the company's partner Akeso announced positive top-line results from the phase III HARMONi-GI1 study conducted in China in certain patients with biliary tract cancer (BTC). The study evaluated ivonescimab plus chemotherapy versus AstraZeneca AZN's blockbuster cancer drug Imfinzi (durvalumab) plus chemotherapy as a first-line treatment in patients with advanced BTC, a rare group of cancers affecting the bile ducts and gallbladder. Imfinzi, a PD-L1 monoclonal antibody, holds approvals across multiple cancer indications and is a key

BiotechClinical TrialsNsclcOncologyPhase Iii
Published
27 Aug 2026 16:11
News subject
Earnings
Why this score
Positive financial language
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 20.4d old
Duplicates
1 consolidated
#1062Tone
finance.yahoo.comDirect company coverageStored article

Summit Therapeutics (SMMT) Stock Climbed, So What Is Behind The Move?

Summit Therapeutics (SMMT) drew fresh attention after partner Akeso reported positive topline results from the Phase III HARMONi-GI1 trial of ivonescimab plus chemotherapy in advanced biliary tract cancer, highlighting another late stage data point around the drug. The HARMONi-GI1 update arrived alongside a series of recent ivonescimab milestones for Summit Therapeutics, and traders reacted quickly. The 1-day share price return was 6.51%, and the 7-day and 30-day share price returns were 8.54% and 8.58% respectively. However, the year-to-date share price return is down 18.78% and the 1-year to

BiotechClinical TrialsIntrinsic ValuePharmaRevenue GrowthShare Price
Published
27 Aug 2026 11:06
News subject
Earnings
Why this score
Positive market reaction
Company focus
Shared story ยท 78%
How it is used
Direct company coverage
Story strength
Medium ยท 36/100
30-day weight
6.9% of the score ยท 20.6d old
Duplicates
1 consolidated
#11Not directional
finance.yahoo.comDirect company coverageStored article

Summit Therapeutics (SMMT) Published Phase III HARMONi Results In The Lancet Oncology

Summit Therapeutics (NasdaqGM:SMMT) reported that Phase III HARMONi trial results for ivonescimab in EGFR-mutated NSCLC have been published in The Lancet Oncology. The pivotal data show significant clinical benefit for patients in the HARMONi study, according to the published results. The company highlighted that ivonescimab for EGFR-mutated NSCLC is currently under ongoing FDA regulatory review. The growing flow of late stage oncology and immunotherapy data makes it worth looking at companies applying similar approaches in AI driven drug discovery and clinical development through 74 profitabl

BiotechClinical TrialsFda Approval
Published
27 Aug 2026 06:13
News subject
Earnings
Why this score
The headline reports news without a clear direction
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 20.8d old
Duplicates
1 consolidated
#12Not directional
finance.yahoo.comDirect company coverageStored article

Summit Therapeutics (SMMT) Is Up 8.5% After New Phase III Biliary Cancer Data For Ivonescimab

Summit Therapeutics reported that partner Akeso recently delivered positive topline Phase III HARMONi-GI1 data from China, where ivonescimab plus chemotherapy achieved statistically significant and clinically meaningful overall survival, progression-free survival, and response rate benefits over durvalumab plus chemotherapy in first-line advanced biliary tract cancer. This adds a second late-stage success for ivonescimab alongside the previously published HARMONi non-small cell lung cancer results and ongoing FDA review, reinforcing its potential as a bispecific PD-1/VEGF antibody across multi

BiotechClinical TrialsFda ApprovalPharma
Published
27 Aug 2026 03:14
News subject
Regulatory and legal
Why this score
Positive financial language
Company focus
Shared story ยท 78%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 20.9d old
Duplicates
1 consolidated
#13Not directional
finance.yahoo.comDirect company coverageStored article

Ivonescimab Plus Chemotherapy Global Phase III HARMONi Primary Analysis Results Published in The Lancet Oncology

First Immunotherapy-Based Regimen to Show Statistically Significant and Clinically Meaningful PFS Benefit in a Global Phase III Study of EGFR-Mutated NSCLC after Third-Generation EGFR TKI Progression Updated OS Data to Be Presented at WCLC 2026 MIAMI, August 25, 2026--(BUSINESS WIRE)--Summit Therapeutics Inc. (NASDAQ: SMMT) today announced the publication of primary analysis results from the global Phase III HARMONi clinical trial in The Lancet Oncology. In HARMONi, ivonescimab in combination with platinum-doublet chemotherapy demonstrated a statistically significant and clinically meaningful

Clinical TrialsFda ApprovalFourth QuarterImmunotherapyLung Cancer
Published
25 Aug 2026 11:00
News subject
Earnings
Why this score
The headline reports news without a clear direction
Company focus
Company discussed ยท 86%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 22.6d old
Duplicates
1 consolidated
#1463Tone
finance.yahoo.comDirect company coverageStored article

Summit Therapeutics Shares Rise After Bernstein SocGen Upgrade

Researcher looking through microscope ยฉAdobe Stock Images Summit Therapeutics (NASDAQ:SMMT) shares gained 1.1% in pre-market trading after Bernstein SocGen upgraded the biotechnology company to Market Perform from Underperform and raised its price target to $11.90 from $9.80. The broker said Summit's current valuation now provides a more appropriate reflection of the risk-adjusted intrinsic value of ivonescimab, the company's only late-stage drug candidate. However, Bernstein stopped short of adopting a bullish position, arguing that the treatment is unlikely to emerge as a broad replacement f

BiotechClinical TrialsFda ApprovalIntrinsic ValuePrice Target
Published
25 Aug 2026 10:51
News subject
Analyst action
Why this score
Analyst upgrade
Company focus
Shared story ยท 78%
How it is used
Direct company coverage
Story strength
Low ยท 33/100
30-day weight
0.5% of the score ยท 22.6d old
Duplicates
1 consolidated

Earlier company news

SMMT news archive

37 older headlines

Stored newest first for historical research. It starts after the newest three pages above and then continues through older news. Each archive page is loaded only when it is opened.

Older news is kept in the archive

There are 37 older SMMT headlines. Open one page at a time when you need them.

Open older archive

Provider matches checked

Provider mentions not used in the score

3 not scored

A news provider linked these stories to SMMT, but the headline and available text are not mainly about Summit Therapeutics Inc.. They are kept here for transparency and do not affect the score, confidence, history or wider market totals.

Provider mentions are kept separate

Open the list to see which provider matches were checked and left out of SMMT sentiment.

Open provider mentions

How the page works

How to read the score

The score shows direction

It describes the weighted balance of qualifying headlines. A score of 50 can mean balanced news or that there is not enough evidence; the status label explains which.

Confidence is separate

Confidence measures depth, source breadth, direct relevance, freshness and agreement. It does not rise merely because the tone is extreme.

Price is confirmation

Weekly price response, trend and fair-value position test whether the market is accepting or rejecting the news. They never rewrite the news score.

What the page does

It measures news already published. It is not a forecast, recommendation or price target.

Evidence context