Weekly structural research ยท NASDAQ ยท Healthcare

GLUE Stage Analysis

Monte Rosa Therapeutics Inc

Week ending 9 Oct 2026Close USD 10.30Tenure DevelopingBenchmark QQQ
Executive diagnosis

What the Activity Line geometry says now

Structure, not prediction
Downward Expansion ยท Early contraction

The weekly architecture is expanding downward.

Trend and Activity show sustained negative alignment with weak price acceptance. Repair requires persistent improvement across the structure, not merely one strong observation.

  • The Trend gate is down within the current regime.
  • Fast Activity versus Slow Activity: weakening.
  • Activity structure: wide and expanding.
Direction -75โˆ’100 bearish to +100 bullish
Energy 85/100directional strength
Maturity 30/100lifecycle context
Confidence 90/100evidence agreement
Trend gate Downstructural direction
Activity structure Wideexpanding separation
Price acceptance -83.3%position within the Activity structure
Fair Value context +10.1%USD 9.36 ยท weakening
Trend Architecture map ยท Historical context

Weekly close, Activity, Trend and Fair Value

Follow price and Trend first, then add Activity Lines to inspect the structure. Subtle bands show the regime recognized at each completed observation; the dashed line marks current Fair Value, not a historical forecast.

CloseTrendCurrent Fair Value
Background stage key
  • BalanceDirection is contained.
  • Rotation UpStructure is turning higher.
  • Upward ExpansionUptrend is established.
  • DecelerationUptrend is losing energy.
  • Rotation DownStructure is turning lower.
  • Downward ExpansionDowntrend is established.
View chart values ยท 156 observations
WeekCloseTrendRelative StrengthVolumeRegimeDirectionEnergy
2026-10-0910.3017.27-47.527972149Downward Expansion-7585
2026-10-0210.5017.46-46.527314820Downward Expansion-7881
2026-09-2511.7717.70-39.595462984Downward Expansion-7475
2026-09-1812.1317.90-35.537534869Downward Expansion-7573
2026-09-1114.0718.13-24.194581862Downward Expansion-6574
2026-09-0413.8418.26-25.224913696Rotation Down-6978
2026-08-2813.3818.45-26.866061136Rotation Down-4769
2026-08-2114.3018.68-20.905008849Balance-3644
2026-08-1415.5018.97-15.673511646Balance-2935
2026-08-0715.8819.24-11.759232816Balance-1315
2026-07-3116.5219.52-2.4412821651Upward Expansion2118
2026-07-2422.7819.4836.913939995Upward Expansion6374
2026-07-1724.5619.3047.975954756Upward Expansion7480
2026-07-1023.0419.0035.746998242Upward Expansion6672
2026-07-0324.2118.7747.956933903Balance7869
2026-06-2622.2918.5540.3513527867Balance5628
2026-06-1918.3118.3412.325232676Balance-35
2026-06-1218.2418.2116.476231939Balance-15
2026-06-0516.3718.088.504541350Deceleration15
2026-05-2919.7117.9426.323734363Deceleration4423
2026-05-2218.8117.7126.173846416Deceleration4422
2026-05-1518.1517.4625.363762328Deceleration4629
2026-05-0819.3917.1935.793650986Deceleration4436
2026-05-0118.8016.8841.453228009Deceleration3832
2026-04-2419.7916.5153.854849039Deceleration4532
2026-04-1719.7816.1060.204493295Deceleration3920
2026-04-1017.4815.6553.453876102Deceleration319
2026-04-0317.0915.2359.906310314Deceleration317
2026-03-2715.3814.8252.826105675Deceleration-318
2026-03-2015.6314.4752.999698002Deceleration014
2026-03-1316.0214.1156.254066804Deceleration1817
2026-03-0617.8013.7374.564750181Deceleration3023
2026-02-2717.7513.2875.205242673Deceleration3524
2026-02-2018.9812.8590.914139641Upward Expansion4128
2026-02-1317.9212.4186.554585317Upward Expansion4840
2026-02-0619.5512.01105.175646991Upward Expansion6358
2026-01-3020.5211.53116.205481190Upward Expansion6678
2026-01-2322.8411.00146.595225876Upward Expansion7375
2026-01-1623.7110.40165.587606328Upward Expansion8672
2026-01-0924.289.76179.8435041978Upward Expansion9170
2026-01-0215.319.1287.502814635Upward Expansion6357
2025-12-2617.298.77111.473253599Upward Expansion7468
2025-12-1915.548.3496.5011458189Upward Expansion6766
2025-12-1216.317.95111.113763689Upward Expansion7169
2025-12-0517.417.54125.293742798Upward Expansion8875
2025-11-2816.177.09114.653779533Upward Expansion8975
2025-11-2114.226.7299.893629723Upward Expansion8084
2025-11-1414.366.4297.916636305Upward Expansion9092
2025-11-0712.316.0971.604418018Upward Expansion7991
2025-10-3112.855.8274.226849315Upward Expansion9498
2025-10-2411.145.5254.494203617Upward Expansion9096
2025-10-1710.055.3244.345803109Upward Expansion8795
2025-10-1010.045.1849.088740043Upward Expansion9497
2025-10-037.745.0513.663852497Upward Expansion8588
2025-09-267.495.0111.764662908Upward Expansion8579
2025-09-196.334.94-5.6740369769Balance4340
2025-09-124.814.94-27.141564740Balance-229
2025-09-054.945.00-24.401391285Balance-2114
2025-08-294.805.06-26.331540959Balance-3626
2025-08-224.825.13-26.791832318Balance-3527
2025-08-154.585.15-31.642125201Balance-3721
2025-08-084.385.19-34.521884978Rotation Up-3420
2025-08-014.795.23-25.862633526Rotation Up1325
2025-07-255.675.31-14.232094894Balance2741
2025-07-185.945.36-9.342541308Balance1521
2025-07-115.165.39-20.042107054Balance-99
2025-07-044.875.47-24.741210480Downward Expansion-3017
2025-06-274.605.62-27.692597038Downward Expansion-3220
2025-06-204.635.81-24.131798987Downward Expansion-3619
2025-06-134.915.94-19.411874147Downward Expansion-4127
2025-06-065.016.03-18.052610270Downward Expansion-5640
2025-05-304.186.18-30.112421515Downward Expansion-6054
2025-05-233.976.33-32.462162090Downward Expansion-6549
2025-05-163.986.36-34.031870469Downward Expansion-6746
2025-05-094.096.42-28.021913845Downward Expansion-6846
2025-05-024.976.44-13.071601747Downward Expansion-5849
2025-04-255.066.45-8.882917369Downward Expansion-6270
2025-04-184.556.45-13.063615522Downward Expansion-6476
2025-04-114.226.52-21.706609328Downward Expansion-7378
2025-04-043.956.58-22.124161939Downward Expansion-7971
2025-03-285.106.64-10.353453329Downward Expansion-6751
2025-03-215.806.67-1.226873656Balance-3033
2025-03-146.276.696.162286298Balance-2225
2025-03-076.396.645.234061026Balance-2115
2025-02-285.506.55-12.541995702Balance-2516
2025-02-216.226.50-4.961875142Balance-36
2025-02-146.786.451.061928624Deceleration-27
2025-02-076.746.373.181852446Deceleration-1421
2025-01-316.666.292.353772656Deceleration-1727
2025-01-245.526.19-16.132752469Deceleration-2024
2025-01-175.666.13-13.115279073Deceleration015
2025-01-105.706.06-10.086023742Deceleration1117
2025-01-037.176.0010.042841961Deceleration3123
2024-12-277.065.897.493213551Deceleration3720
2024-12-206.935.796.429930733Upward Expansion4432
2024-12-137.565.7013.3611582936Upward Expansion5945
2024-12-069.415.6242.5911325458Upward Expansion6666
2024-11-2910.365.4763.843233666Upward Expansion7982
2024-11-228.495.3137.944504147Upward Expansion6476
2024-11-157.745.2129.965394247Upward Expansion5669
2024-11-089.265.1551.838132473Upward Expansion7774
2024-11-018.905.0856.33104656287Deceleration7349
2024-10-254.895.02-14.28545182Deceleration-411
2024-10-185.525.09-2.791021728Deceleration412
2024-10-114.935.16-12.496799294Rotation Up57
2024-10-045.095.21-9.031206255Rotation Up1516
2024-09-275.175.25-8.041819724Rotation Up2928
2024-09-206.485.2915.903555231Rotation Up3355
2024-09-136.085.269.751455537Rotation Up2756
2024-09-065.695.268.18652537Rotation Up1943
2024-08-306.175.239.891301073Rotation Up3339
2024-08-236.335.1811.211484696Rotation Up1420
2024-08-164.685.15-17.38719631Downward Expansion-3519
2024-08-093.945.17-27.56949768Downward Expansion-4526
2024-08-024.015.23-27.12850174Downward Expansion-4223
2024-07-264.675.28-18.97949357Downward Expansion-4226
2024-07-194.265.32-28.921387595Downward Expansion-4837
2024-07-124.325.37-31.801040444Downward Expansion-6252
2024-07-053.645.39-43.521187692Downward Expansion-6770
2024-06-283.745.41-40.871391998Downward Expansion-6774
2024-06-213.635.39-43.541548773Rotation Down-7174
2024-06-143.835.37-41.26878899Rotation Down-4362
2024-06-073.985.35-37.941512283Rotation Down-4360
2024-05-314.125.33-34.93651564Rotation Down-3554
2024-05-244.165.31-36.411282443Deceleration-3442
2024-05-175.205.26-20.371913848Deceleration-1726
2024-05-104.855.18-24.65772934Deceleration-319
2024-05-035.655.18-11.66595044Deceleration2419
2024-04-265.335.16-16.15500363Upward Expansion2815
2024-04-195.855.14-4.56652264Upward Expansion5534
2024-04-127.215.1510.70648639Upward Expansion6460
2024-04-057.075.117.29721111Upward Expansion6258
2024-03-297.055.074.82787065Upward Expansion6463
2024-03-227.715.0412.80878862Upward Expansion7972
2024-03-156.414.99-3.95848025Upward Expansion6157
2024-03-086.294.98-7.88456446Upward Expansion6153
2024-03-016.305.00-9.84756951Balance3431
2024-02-235.725.02-17.20290479Balance2516
2024-02-165.965.06-13.321008981Balance2113
2024-02-094.875.10-30.99474638Balance-27
2024-02-024.725.17-32.82486888Rotation Up49
2024-01-265.435.23-23.21487896Rotation Up1923
2024-01-195.055.28-29.16727200Rotation Up2239
2024-01-126.005.34-14.861225577Rotation Up3037
2024-01-055.525.39-20.20920429Rotation Up2337
2023-12-295.655.43-22.30725657Downward Expansion729
2023-12-225.745.49-22.061511589Downward Expansion-519
2023-12-155.005.51-32.601940591Downward Expansion-3422
2023-12-084.335.53-40.991604905Downward Expansion-4840
2023-12-013.125.58-58.081506339Downward Expansion-6557
2023-11-242.975.64-61.05382906Downward Expansion-7061
2023-11-173.355.70-56.62846536Downward Expansion-6573
2023-11-103.215.78-58.541007602Downward Expansion-6987
2023-11-033.585.90-53.431280665Downward Expansion-6887
2023-10-272.786.05-62.241538282Downward Expansion-8995
2023-10-202.746.22-64.505157139Downward Expansion-9593
Price vs TrendBelow-40.3%
Trend directionFalling-11.6%
Price vs current Fair ValuePremium+10.1%
Fair Value directionMoving away-157.5%
Relative Strength vs benchmarkLagging-47.5%
Relative strength directionWeakening-83.3%
Price momentumNegative-41.1%
Volume balanceSupply-led0.22ร—
Beyond the current label

Is the structure strengthening or losing force?

Direction and energy measure different things

Direction shows the upward or downward lean. Energy shows the force behind the structural move: high energy can accompany a strong decline as well as an advance.

Direction

-75 / ยฑ100

-10.2 points since 2026-09-11

Energy

85 /100

+11.3 points since 2026-09-11

Recent change compares the latest reading with four observations earlier. Missing readings remain unavailable. Use the chart values above to inspect individual observations.

Comparative structural evidence

Why this architecture regime won

Every regime is evaluated
Balance13
Rotation Up12
Upward Expansion20
Deceleration37
Rotation Down77
Downward Expansion96

The winning regime is the state most consistent with the complete SM evidence set. Direction, energy, maturity and confidence describe different aspects of the current structure, while contradictory evidence remains visible rather than being averaged into false certainty.

Time spent in each state

The context behind todayโ€™s regime

2023-10-20 to 2026-10-09 ยท 156 classified observations out of 156 shown.

Balance 16%Rotation Up 10%Upward Expansion 26%Deceleration 19%Rotation Down 4%Downward Expansion 25%
Recent Trend Architecture ledger
RegimeRecognizedLast observationTenureMove inside regime
Downward Expansion2026-09-112026-10-09Developing-26.8%
Rotation Down2026-08-282026-09-04New+3.4%
Balance2026-08-072026-08-21New-9.9%
Upward Expansion2026-07-102026-07-31New-28.3%
Balance2026-06-122026-07-03New+32.8%
Deceleration2026-02-272026-06-05Established-7.8%
Upward Expansion2025-09-262026-02-20Established+153.4%
Balance2025-08-152025-09-19Developing+38.2%
Rotation Up2025-08-012025-08-08New-8.6%
Balance2025-07-112025-07-25New+9.9%
Downward Expansion2025-03-282025-07-04Established-4.5%
Balance2025-02-212025-03-21Developing-6.8%
Deceleration2024-12-272025-02-14Developing-4.0%
Upward Expansion2024-11-082024-12-20Developing-25.2%
Classic Stage Analysis comparison
Stage 1 ยท Basing34
Stage 2 ยท Advancing0
Stage 3 ยท Distribution36
Stage 4 ยท Declining100

Legacy result: Stage 4 ยท Stage 4B ยท Declining. It remains visible while the experimental architecture is validated rather than being silently discarded.

Leadership versus QQQ

Is relative performance confirming the geometry?

Confirmation, not classification

Relative Strength

The security is compared with its market benchmark on the SM scale. Above zero indicates relative leadership; direction shows whether that leadership is improving or weakening.

Confirmation evidence

Lagging benchmark

Architecture confirmation
100/100
Current Relative Strength
-47.52
Relative Strength direction
Weakening
Price momentum
-41.1%
Excess performance vs benchmark
-64.0%
Healthcare regime cohort
90th percentile286 in cohort
Participation and structure

Is demand confirming the architecture?

Volume cannot overrule geometry
Relative volume1.21ร—

Latest completed volume relative to typical participation.

Up/down volume0.22ร—

Participation balance between advancing and declining observations.

Accumulation / distribution0 / 5

Recent participation evidence classified by demand and supply.

Activity alignment+0.0%

Current positive alignment across Activity and Trend.

Fast/slow rotationWeakening

Current relationship between Fast Activity and Slow Activity.

Structure stability+25.0%

Whether recent Activity evidence is stable or remains in balance.

Weekly volume with architecture context

Bars show completed weekly volume; the dashed line provides typical-volume context. Both measures use the same scale.

Decision architecture

References that would change the structural read

Evidence levels, not orders
Fast Activity USD 11.14falling
Slow Activity USD 16.25falling
Trend Reference USD 17.27-40.3% close margin
Current Fair Value USD 9.36+10.1% close margin
Structural low USD 9.68shock / repair context
What changes the read?

Fan contraction and a persistent upward fast/slow rotation are required before the declining structure is considered repaired.

Range context +23.8%
Annualized volatility +74.0%
From structural high -60.0%
From structural low +15.2%
Point-in-time evidence

What followed this architecture in this market?

Descriptive history, never a forecast

Historical comparisons use only the structural read that would have been available at each completed observation. Independent observations are used where possible, with benchmark comparison beginning after each recognized state.

Outcome horizon Samples Median movePositive periodsDirectional follow-through Median excess vs QQQ Regime survived Read
Near term16+3.0%-42.0% to +93.3%+50.0%+50.0%-3.8%+75.0%Usable descriptive sample
Intermediate7+24.8%-39.1% to +62.8%+71.4%+28.6%+16.2%+42.9%Usable descriptive sample
Extended4+47.0%-5.0% to +88.8%+75.0%+25.0%+21.1%+0.0%Too little matched history
Full cycle3+23.0%-27.1% to +384.6%+66.7%+33.3%+8.0%+33.3%Too little matched history
Evidence framework

What the analysis measures and where its limits lie

Trend Architecture

Trend Architecture brings Price, Fast Activity, Slow Activity and Trend into one structural read. It identifies balance, rotation, expansion, deceleration and contraction while requiring persistent evidence for confirmed regime changes.

Evidence roles

Trend, Activity, relative strength, volume and Fair Value each have a defined role in the SM evidence framework. No single reading is treated as sufficient on its own, and conflicting evidence remains visible.

Fair Value and RS

Current Fair Value provides a long-term price anchor and shows whether price is trading above, below or repairing toward that reference. Relative Strength compares the security with its benchmark and shows whether leadership is improving or weakening.

Known limitations

Weekly structure recognizes conditions after they develop. Event gaps can bypass smooth transitions, sideways markets can rotate repeatedly, and historical samples for a particular regime can be thin.

Independent market research for education. Not investment advice, a recommendation, a forecast, a target, or an execution instruction. Historical regime behaviour does not establish what happens next.

Evidence context