TLPH NASDAQ Week ended 24 Jul 2026

Weekly Investor Report

Talphera Inc. · Healthcare · Drug Manufacturers - Specialty & Generic

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Latest close 1.35 USD
1.9% latest week
Weekly setup

Constructive, but selective

The weekly trend is active. Price is 44.3% above the Trend Line and sits at 81.4% of its 52-week range. The latest completed week returned 1.9%, after a 31.1% four-week move. The latest factor snapshot indicates quality is middle-of-the-pack; growth is moderate; valuation is neither clearly cheap nor expensive. Options positioning is bearish with 41/100 conviction, while the latest news-sentiment score is 52/100. Near-term considerations: volume confirmation is below normal; earnings are due in 14d.

Setup score 51 out of 100
Latest Close 1.35 USD 24 Jul 2026
1W Return 1.9% latest completed week
4W Return 31.1% short-term follow-through
12W Return 47.0% quarterly tape
Trend Breadth 44.2% 23 of 52 weeks active
Volume Ratio 0.6x vs 13-week average
What is working
  • The trend backdrop is active with a 2-week active streak.
  • Price is above the Trend Line, keeping the weekly tape constructive.
  • Price is above Fair Value, showing premium demand versus the model.
  • Activity pressure is positive on the latest completed week.
What could go wrong
  • Next-week expectancy is negative at 38.06% based on similar historical setup states.
  • Activity pressure is weak, so confirmation is not yet broad enough.
  • 2 reversal markers appear in the recent smart-money tape.
What to watch next
  • Trend Line remains the key weekly regime level.
  • Activity pressure is the gauge to monitor for confirmation or fade.
  • A volume ratio above 1.5x would show stronger participation in the next move.
Price follow-through 1.9% Latest completed week; four-week move 31.1%. Indicator stack 31/82 Trend and activity pressure are weighted against the latest 12-week confirmation window. Trend backdrop Active The trend backdrop defines the current weekly regime. Patient Capital Quiet Activity-pressure buy-signal status for institutional accumulation timing. Next-Week Expectancy Negative 38.06% Historical one-week expectancy contributes to the evidence score when direction is confirmed. Options pressure Bearish 41/100 conviction; expected move 103.3%. News sentiment 52/100 45 relevant articles in the latest sentiment read. Event risk 14d Next report is scheduled for 13 Aug 2026; event risk rises as the date approaches.
01 · Price action

Where price is—and whether the trend supports it

The weekly trend is active. Price is 44.3% above the Trend Line and sits at 81.4% of its 52-week range. The latest completed week returned 1.9%, after a 31.1% four-week move.

Study the full chart

52-week price path

Price vs Trend Line and Fair Value
Price Trend Line Fair Value
02 · Volume and demand

Is real participation confirming the move?

Latest weekly volume is 0.6x the 13-week average. Participation is below its recent norm, so price strength is not receiving full volume confirmation.

26-week volume confirmation

Bar height shows volume; colour shows the weekly price direction
30 Jan 6 Feb 13 Feb 20 Feb 27 Feb 6 Mar 13 Mar 20 Mar 27 Mar 3 Apr 10 Apr 17 Apr 24 Apr 1 May 8 May 15 May 22 May 29 May 5 Jun 12 Jun 19 Jun 26 Jun 3 Jul 10 Jul 17 Jul 24 Jul
Up week Down week
Demand beneath price

Activity pressure and institutional-style signals

These indicators assess whether participation is improving beneath the headline price move. They are supporting evidence, not proof of institutional buying.

Activity pressure path

Latest 0.4412-week average 0.16

12-week confirmation

Trend active2/12Active trend-backdrop weeks in the latest 12-week window.
Positive pressure10/12Weeks with constructive activity pressure in the latest 12-week window.
Positive leadership6/12Weeks with positive relative leadership in the latest 12-week window.
Activity pressure0.44Current proprietary activity-pressure read.
Buy signals0Accumulation signal count in the latest 12 weeks.
Reversal markers22 reversal markers

No recent accumulation markers. 2 reversal markers.

03 · Momentum and leadership

Is performance persistent—and is the stock leading?

Performance is 31.1% over four weeks, 47.0% over 12 weeks, and 219.1% over one year. The current trend has remained active for 2 consecutive weeks.

Performance by holding period

1W1.9%
4W31.1%
12W47.0%
26W35.0%
52W219.1%
Active trend streak2 weeks
Active weeks in one year23
Trend breadth44.2%

Activity pressure vs relative leadership

Activity pressureRelative leadership
Pressure1.42Latest activity-pressure read.
Pressure change81.0%Four-week change in activity pressure.
Leadership31.68Latest relative-leadership reading.
RS change1040.5%Four-week change in relative leadership.
04 · Fundamentals and valuation

What investors are paying for—and the quality behind it

The latest factor snapshot indicates quality is middle-of-the-pack; growth is moderate; valuation is neither clearly cheap nor expensive.

Open full factor analysis
Factor week 26 Jul 2026 Financial statements through 31 Dec 2025 Field coverage 82% Model confidence 78%

Relative factor standing

Higher display scores are better. Each score is converted from the underlying universe rank, where rank 1 is best.

Overall factor strength34/100Blend of value, momentum, and quality. Underlying universe rank 67; rank 1 is best.
Value43/100Relative valuation strength. Underlying universe rank 58; rank 1 is best.
Quality41/100Profitability and accounting quality. Underlying universe rank 60; rank 1 is best.
Momentum43/100Medium-term price momentum. Underlying universe rank 58; rank 1 is best.
Growth43/100Revenue and earnings growth. Underlying universe rank 58; rank 1 is best.
How to read this

Quality and valuation are separate questions

A strong company can still carry a demanding valuation. This report shows profitability, growth, balance-sheet strength, and the price paid for those characteristics separately.

Valuation

How much investors are paying for earnings, sales, and cash flow.

P/E
-
Price divided by trailing earnings.
Price / sales
-
Market value relative to trailing revenue.
EV / EBITDA
-
Enterprise value relative to operating cash earnings.
Free-cash-flow yield
-15.5%
Free cash flow as a share of enterprise value.

Business quality

Margins and the return generated on invested capital.

Gross margin
2800.0%
Gross profit retained from each unit of revenue.
Operating margin
-1451600.0%
Operating profit retained from revenue.
Free-cash-flow margin
-1129400.0%
Free cash flow generated from revenue.
Return on invested capital
-51.5%
Operating return generated on invested capital.

Growth and financial strength

Recent business growth and accounting strength.

Revenue growth
-100.0%
Latest one-year revenue growth.
EPS growth
-
Latest one-year earnings-per-share growth.
Free-cash-flow growth
-
Latest one-year free-cash-flow growth.
Piotroski F-score
3/9
Nine-point accounting-strength checklist.

Shareholder return and balance sheet

Cash returned to owners and financial leverage.

Dividend yield
-
Cash dividends relative to market value.
Buyback yield
0.0%
Net share repurchases relative to market value.
Shareholder yield
0.0%
Dividend yield plus net buyback yield.
Net debt / EBITDA
-0.2x
Balance-sheet debt relative to operating cash earnings.
05 · Ownership, options, and sentiment

What other market participants are doing

Options, insider transactions, market sentiment, and activity-pressure signals can confirm or challenge the price story. None should be used alone.

Options positioningBearish

TLPH shows bearish options pressure with a 41/100 conviction score, put-call volume ratio of 3.00, expected move of 103.3%, and Sharemaestro trend signal active.

Conviction41/100
Expected move103.3%
Put/call volume3.00
Pressure-42
Speculation0
Volatility96
Trend agreement53
Open options detail
Insider activity-

No recent insider transactions are stored for this company.

News sentiment52/100

Weighted news tone is neutral across 45 relevant articles.

8 positive · 35 neutral · 2 negative
Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal
06 · Catalysts and risk

What can move the shares—and how volatile the path has been

Event timing, options-implied movement, drawdown, and weekly return distribution frame the risk around the current setup.

Next earnings14dNext report is scheduled for 13 Aug 2026; event risk rises as the date approaches.
Options expected move103.3%Nearest-chain priced movement where available.
52-week drawdown-14.0%Distance below the 52-week high.
13-week volatility13.4%Standard deviation of weekly returns.

Weekly gains and losses

Latest 26 completed weeks

Each bar is one week. Gains rise above the zero line; losses fall below it. Taller bars mean a larger weekly move.

Weeks higher11 of 2615 weeks finished lower.
Best week+36.4%Week of 10 Jul.
Worst week-14.8%Week of 6 Feb.
Latest week+1.9%Week of 24 Jul.

Shape of recent returns

Strong gains8
Modest gains3
Flat weeks0
Modest losses5
Sharp losses10
Recent vol13.4%13-week weekly-return volatility.
Base vol14.1%52-week weekly-return volatility.
Up/down split25/26Count of positive and negative weeks in the 52-week window.
Average skew12.5% / -5.9%Average positive week versus average negative week.
07 · Sector and peer context

Is this stock leading—or simply moving with its group?

Sector and industry breadth distinguish company-specific strength from a broad group move.

08 · Evidence and weekly data

The underlying research record

Every top-level statement above should be traceable to a stored market, fundamental, event, or positioning observation.

Weekly tape45/100

Trend, activity pressure, participation, and risk combine to a 45/100 tape read.

 Indicator analysis43/100

Latest 12-week confirmation: trend 2/12, activity pressure 10/12, relative leadership 6/12.

Activity pressure 0.44; 2 reversal markers Next-Week ExpectancyNegative 38.06%

Next-week expectancy is negative with a 38.06% historical one-week setup read.

Adds short-term historical context without overriding trend, activity, or relative leadership. Factors39/100

O'Shaughnessy factor stack blends value, quality, momentum, and confidence.

Buyback Yield rank 52; Small Cap Core rank 59 Patient CapitalQuiet

Activity-pressure buy-signal evidence highlights potential institutional accumulation windows.

No recent buy signal Options45/100

TLPH shows bearish options pressure with a 41/100 conviction score, put-call volume ratio of 3.00, expected move of 103.3%, and Sharemaestro trend signal active.

Bearish · Put-side pressure · Expected move 103.3% Sentiment52/100

Weighted news tone is neutral across 45 relevant articles.

Talphera Inc (TLPH) Technical Analysis: Support, Resistance, Indicators & Moving Averages Insiders50/100

No recent insider transaction evidence is stored.

 Earnings14d

Next report is scheduled for 13 Aug 2026; event risk rises as the date approaches.
WeekCloseReturnTrend LineFair ValuePressureLeadershipVolumeTrend
24 Jul 20261.35 USD1.9%0.94 USD0.84 USD1.4231.68819.4KOn
17 Jul 20261.32 USD-9.2%0.93 USD0.84 USD1.4229.211.8MOn
10 Jul 20261.46 USD36.4%0.92 USD0.83 USD1.3838.574.8MOff
3 Jul 20261.07 USD3.9%0.91 USD0.83 USD1.164.881.2MOff
26 Jun 20261.03 USD-5.5%0.92 USD0.83 USD0.782.781.6MOff
19 Jun 20261.09 USD24.8%0.93 USD0.83 USD0.474.721.5MOff
12 Jun 20260.87 USD12.7%0.93 USD0.83 USD0.18-13.131.0MOff
5 Jun 20260.78 USD-5.0%0.95 USD0.84 USD0.09-20.83657.4KOff
29 May 20260.82 USD0.1%0.96 USD0.84 USD0.16-20.25466.3KOff
22 May 20260.82 USD-3.9%0.98 USD0.84 USD0.20-17.85735.9KOff
15 May 20260.85 USD-6.2%0.99 USD0.84 USD-0.01-13.33884.1KOff
8 May 20260.90 USD-1.6%1.00 USD0.84 USD-0.29-7.65487.7KOff
1 May 20260.92 USD18.5%1.01 USD0.84 USD-0.60-0.74954.1KOff
24 Apr 20260.78 USD-3.4%1.01 USD0.84 USD-0.92-14.64583.8KOff
How to use this report

This is a completed-week research summary. It explains the available evidence and its conflicts; it does not predict a guaranteed outcome or replace your own risk assessment. Fundamental figures may refer to an earlier financial reporting period, which is shown above.