Sharemaestro company-news research for Alto Neuroscience, Inc. (ANRO), showing current tone, evidence confidence, direct company coverage, sector and industry context, completed price response and the source headlines used on the page. Scores describe published news evidence. Confidence describes the amount, freshness, source breadth and direct company relevance of that evidence. Price context is shown separately.

NYSE United States Provisional evidence

Company news sentiment

Latest ANRO news and sentiment

Alto Neuroscience, Inc.

Company headlines from the last 30 days, weighted by freshness, relevance, publisher quality and the strength of the wording. Price is shown separately.

Latest weekly closeUSD 24.80week of 2 Oct 2026
Main news subjectMarket update91/100 share of current news
News data statusPartial17 duplicate stories removed

Current company news

Early balanced news score

11 company-specific stories are available, but there are not yet enough fresh stories from separate publishers for a firm reading.

Observed headline tone41/100 Published 30-day score49/100

Older, less relevant and less reliable stories count for less. Confidence is shown separately.

Latest source headline At $2.32 a share, Alto Neuroscience (ANRO) CFO exercises options for 55,000 shares. Stock Titan ยท 05 Oct 2026 20:59

What supports the score

Direct evidence

11 current stories are mapped specifically to ANRO.

Source breadth

The score uses 5 publishers rather than depending on one outlet.

What limits the score

Too little evidence

The stories agree, but freshness-weighted evidence is only 0.094.

Confidence

Confidence is 20/100, below the threshold for a firm score.

49/100
News scoreEarly balanced news score
20/100
Confidencethin evidence
100%/100
Company news11 company stories
99/100
Story agreement1/100 difference

News history

Daily score and story count over 30 days

Daily weighted evidence ยท gaps mean no reading
14 Sep: 1 stories21 Sep: 1 stories29 Sep: 1 stories02 Oct: 5 stories03 Oct: 1 stories05 Oct: 1 stories 14 Sep: tone 50, 1 stories21 Sep: tone 50, 1 stories29 Sep: tone 50, 1 stories02 Oct: tone 43, 5 stories03 Oct: tone 40, 1 stories05 Oct: tone 50, 1 stories 100500
10 Sep25 Sep09 Oct
News scoreStory count50 baseline

Confidence

How reliable the score is

Separate from direction

Confidence uses the amount of news, separate publishers, direct company relevance, freshness and agreement. A high or low score is not automatically reliable.

Amount of evidence2
0.094 after freshness weighting
Source breadth100
5 independent publishers
Company relevance100
share tied directly to this company
Freshness35
recency-weighted evidence
Agreement99
how closely stories agree
Publisher mix63
less reliance on one publisher

Price and news history

Weekly price and news-score history

Early company-news score

Company-specific news is present, but the evidence has not yet earned enough independent, fresh information weight for price confirmation to be treated as a firm signal.

26 completed price weeks15 comparable news-score weeks
One scoring method across the chart.Stored company headlines are recalculated at each weekly point with the current 30-day freshness weighting. Old published snapshots are left unchanged.
10 Apr 2026: close 22.78, indexed 100.017 Apr 2026: close 27.72, indexed 121.724 Apr 2026: close 24.52, indexed 107.601 May 2026: close 24.94, indexed 109.508 May 2026: close 24.26, indexed 106.515 May 2026: close 22.98, indexed 100.922 May 2026: close 21.22, indexed 93.229 May 2026: close 20.07, indexed 88.105 Jun 2026: close 18.26, indexed 80.212 Jun 2026: close 21.47, indexed 94.219 Jun 2026: close 22.74, indexed 99.826 Jun 2026: close 27.04, indexed 118.703 Jul 2026: close 24.78, indexed 108.810 Jul 2026: close 26.48, indexed 116.217 Jul 2026: close 27.54, indexed 120.924 Jul 2026: close 26.78, indexed 117.631 Jul 2026: close 27.07, indexed 118.807 Aug 2026: close 28.67, indexed 125.914 Aug 2026: close 32.14, indexed 141.121 Aug 2026: close 34.28, indexed 150.528 Aug 2026: close 35.13, indexed 154.204 Sep 2026: close 35.55, indexed 156.111 Sep 2026: close 32.0, indexed 140.518 Sep 2026: close 30.27, indexed 132.925 Sep 2026: close 26.49, indexed 116.302 Oct 2026: close 24.8, indexed 108.9 26 Jun 2026: news score 50, close 27.04, 2 stories5003 Jul 2026: news score 50, close 24.78, 3 stories10 Jul 2026: news score 50, close 26.48, 3 stories17 Jul 2026: news score 50, close 27.54, 5 stories5024 Jul 2026: news score 51, close 26.78, 10 stories31 Jul 2026: news score 52, close 27.07, 21 stories07 Aug 2026: news score 47, close 28.67, 25 stories4714 Aug 2026: news score 57, close 32.14, 39 stories21 Aug 2026: news score 56, close 34.28, 43 stories28 Aug 2026: news score 49, close 35.13, 37 stories4904 Sep 2026: news score 50, close 35.55, 30 stories11 Sep 2026: news score 50, close 32.0, 23 stories18 Sep 2026: news score 50, close 30.27, 7 stories5025 Sep 2026: news score 50, close 26.49, 5 stories02 Oct 2026: news score 48, close 24.8, 9 stories48 Price index 165.2 118.1 71.1 News score 100 50 0
10 Apr07 Jul02 Oct
Weekly close, indexedSentiment score
26-week price+8.9%latest close 24.80
News score change-2first to latest comparable week
One-week response-6.4%Price reacting lower
Fair-value position+95.2%Materially above fair value
WeekNews scoreCloseWeekly move
02 Oct 202648USD 24.8-6.4%
25 Sep 202650USD 26.49-12.5%
18 Sep 202650USD 30.27-5.4%
11 Sep 202650USD 32.0-10.0%
04 Sep 202650USD 35.55+1.2%
28 Aug 202649USD 35.13+2.5%
21 Aug 202656USD 34.28+6.7%
14 Aug 202657USD 32.14+12.1%
Provisional evidence

News subjects

What is shaping the score

Market update
Market update4510 stories ยท 91%
Analyst action421 stories ยท 9%

Source mix

Where the evidence comes from

63/100 independence
Stock Titan463 stories ยท 27%
Moomoo432 stories ยท 18%
TradingView401 stories ยท 9%
Investing.com421 stories ยท 9%
Investing.com Nigeria501 stories ยท 9%
www.marketscreener.com501 stories ยท 9%
Investing.com Canada501 stories ยท 9%

Recurring subjects

Subjects appearing most often

Current evidence
Life Sciences10Finance7Financial Markets5Earnings3IPO1

Earlier readings

How the score has changed

40 comparable readings ยท 108 days
Past and present use the same method.Each point recalculates the previous 30 days of stored company headlines with today's scoring rules. The original stored snapshots remain unchanged.
Comparable move-150 to 49 ยท Broadly stable
Observed range46โ€“5850 is the neutral baseline
Evidence depth11stories at latest stored reading ยท +10
Confidence20/100Provisional ยท +20
21 Jun50 neutral07 Oct 21:50
ConstructiveBalanced or withheldCautious

Changes in the stored score

Scores are rebuilt from stored headlines with the current 30-day method. Days with no change are collapsed.

ObservedScoreMoveConfidenceStoriesStatus
07 Oct 21:5049+020/100 (-4)11 (0)Provisional
05 Oct 23:5949+124/100 (-6)11 (+1)Provisional
03 Oct 23:5948+030/100 (-3)10 (+1)Provisional
02 Oct 23:5948-233/100 (+18)9 (+5)Provisional
29 Sep 23:5950+015/100 (-1)4 (-4)Provisional
21 Sep 23:5950+016/100 (-11)8 (-6)Provisional
14 Sep 23:5950+027/100 (+11)14 (-15)Provisional
09 Sep 23:5950+116/100 (-8)29 (-8)Provisional

Evidence behind the direction

What drives this reading?

4 directional stories ยท 4 publisher groups

Shares of weighted directional evidence in 11 retained current headlines. These weights already account for freshness, relevance and publisher limits; they are not additive points of the published score.

Which subjects lean each way

A subject can carry both supportive and cautious news.

SubjectCautious โ† 0 โ†’ Constructive
Analyst action1 story
56.6%0.0%
Market update3 stories
43.4%0.0%

Each side uses the same scale: 0โ€“56.6% of the retained directional evidence.

Where the influence comes from

56.6%largest publisher share

A concentrated reading can depend heavily on one publisher.

Investing.com1 story56.6%
Moomoo1 story18.4%
Stock Titan1 story12.5%
TradingView1 story12.5%

Publisher groups follow the scoring rules. Company disclosures share one group; syndicated stories are consolidated before weighting.

Source headlines

The news behind the score

Showing 1-11 of 11

Only company-specific stories enter this score. The latest 30 days are shown newest first, with newer stories weighted more heavily and duplicate coverage combined.

Alto Neuroscience's President and CFO, Nicholas Conrad Smith, exercised options for 55,000 common shares at $2.32 per share on October 2, 2026. This transaction increased his direct holdings to 79,060 common shares, while he still holds 57,405 options. The options had a vesting schedule tโ€ฆ

Company news retained for context; no directional weight.
Scoring detailsDirect company coverage

Alto Neuroscience's President and CFO, Nicholas Conrad Smith, exercised options for 55,000 common shares at $2.32 per share on October 2, 2026. This transaction increased his direct holdings to 79,060 common shares, while he still holds 57,405 options. The options had a vesting schedule that began in September 2022, with monthly installments thereafter, contingent on continuous service.

Published
05 Oct 2026 20:59
News subject
Market update
Why this score
No clear directional signal in the available text
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 3.4d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
FinanceLife Sciences

An insider at Alto Neuroscience recently sold shares totaling $3,567,247. This transaction was disclosed in a recent SEC filing. The sale indicates a significant divestment by a company insider.

18.4% of directional evidence Medium story strength
Scoring detailsDirect company coverage

An insider at Alto Neuroscience recently sold shares totaling $3,567,247. This transaction was disclosed in a recent SEC filing. The sale indicates a significant divestment by a company insider.

Published
03 Oct 2026 03:58
News subject
Market update
Why this score
Institutional or insider selling
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 39/100
30-day weight
18.4% of directional evidence ยท 6.1d old
Text assessed
Available headline and article text
Duplicates
2 consolidated
FinanceLife Sciences

Nicholas Conrad Smith, President and CFO of Alto Neuroscience (NASDAQ:ANRO), sold approximately $3.57 million in common stock while simultaneously acquiring shares worth $316,982 through exercising employee stock options. These transactions, executed under a 10b5-1 trading plan, occurred โ€ฆ

56.6% of directional evidence Medium story strength
Scoring detailsDirect company coverage

Nicholas Conrad Smith, President and CFO of Alto Neuroscience (NASDAQ:ANRO), sold approximately $3.57 million in common stock while simultaneously acquiring shares worth $316,982 through exercising employee stock options. These transactions, executed under a 10b5-1 trading plan, occurred after ANRO shares surged significantly over the past year, though the stock is currently considered overvalued. The company also recently announced a $100 million stock offering and received a raised price target from H.C. Wainwright following positive development plan updates.

Published
02 Oct 2026 23:59
News subject
Analyst action
Why this score
Institutional or insider selling, Dilution risk, Negative valuation view
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 39/100
30-day weight
56.6% of directional evidence ยท 6.2d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
Financial MarketsLife SciencesFinanceIPO

An officer at Alto Neuroscience (ANRO.US) has sold common stock valued at $3.57 million. This transaction indicates a significant insider sale at the company.

Company news retained for context; no directional weight.
Scoring detailsDirect company coverage

An officer at Alto Neuroscience (ANRO.US) has sold common stock valued at $3.57 million. This transaction indicates a significant insider sale at the company.

Published
02 Oct 2026 12:35
News subject
Market update
Why this score
No clear directional signal in the available text
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 6.7d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
FinanceLife Sciences
—Unscored

This article reports on a Form 4 filing for Alto Neuroscience Inc. for October 1st, published by Investing.com. The piece is brief, primarily serving as an announcement of the filing without providing additional details on its content or implications. It is dated October 2, 2026, at 03:36.

Company news retained for context; no directional weight.
Scoring detailsDirect company coverage

This article reports on a Form 4 filing for Alto Neuroscience Inc. for October 1st, published by Investing.com. The piece is brief, primarily serving as an announcement of the filing without providing additional details on its content or implications. It is dated October 2, 2026, at 03:36.

Published
02 Oct 2026 03:25
News subject
Market update
Why this score
No clear directional signal in the available text
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 7.1d old
Text assessed
Available headline and article text
Duplicates
3 consolidated
EarningsFinanceFinancial MarketsLife Sciences

Nicholas Conrad Smith, President and CFO of Alto Neuroscience (ANRO), sold shares worth over $3.5 million under a Rule 10b5-1 plan. The sales occurred at weighted average prices between $25.7786 and $26.87 per share. Following these transactions, Smith directly owns 24,060 shares of Alto โ€ฆ

12.5% of directional evidence Medium story strength
Scoring detailsDirect company coverage

Nicholas Conrad Smith, President and CFO of Alto Neuroscience (ANRO), sold shares worth over $3.5 million under a Rule 10b5-1 plan. The sales occurred at weighted average prices between $25.7786 and $26.87 per share. Following these transactions, Smith directly owns 24,060 shares of Alto Neuroscience common stock.

Published
02 Oct 2026 01:25
News subject
Market update
Why this score
Institutional or insider selling
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 37/100
30-day weight
12.5% of directional evidence ยท 7.2d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
Financial MarketsLife Sciences

Alto Neuroscience's President and CFO, Nicholas Conrad Smith, exercised options to acquire 134,886 common shares at $2.35 per share on September 29 and 30, 2026, and subsequently sold all of these shares across the same dates. The sales, totaling approximately $3.57 million gross proceedsโ€ฆ

12.5% of directional evidence Medium story strength
Scoring detailsDirect company coverage

Alto Neuroscience's President and CFO, Nicholas Conrad Smith, exercised options to acquire 134,886 common shares at $2.35 per share on September 29 and 30, 2026, and subsequently sold all of these shares across the same dates. The sales, totaling approximately $3.57 million gross proceeds, were executed under a Rule 10b5-1 trading plan adopted on June 30, 2026. This transaction resulted in a pre-tax spread of approximately $3.25 million for Smith.

Published
02 Oct 2026 01:25
News subject
Market update
Why this score
Institutional or insider selling
Company focus
Main company ยท 100%
How it is used
Direct company coverage
Story strength
Medium ยท 37/100
30-day weight
12.5% of directional evidence ยท 7.2d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
EarningsFinanceFinancial MarketsLife Sciences

Nicholas Smith, an officer at Alto Neuroscience (ANRO), has filed a Form 144 notice proposing to sell 134,886 common shares with an aggregate market value of over $3.59 million. The proposed sale, scheduled for September 29, 2026, is tied to the exercise of stock options over the next thrโ€ฆ

Company news retained for context; no directional weight.
Scoring detailsDirect company coverage

Nicholas Smith, an officer at Alto Neuroscience (ANRO), has filed a Form 144 notice proposing to sell 134,886 common shares with an aggregate market value of over $3.59 million. The proposed sale, scheduled for September 29, 2026, is tied to the exercise of stock options over the next three months. This filing indicates that the shares will be acquired and paid for on the dates of their exercise and subsequent sale on the NYSE.

Published
29 Sep 2026 20:34
News subject
Market update
Why this score
Institutional or insider selling
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 9.4d old
Text assessed
Available headline and article text
Duplicates
2 consolidated
FinanceLife Sciences
—Unscored

Alto Neuroscience, Inc. (NYSE: ANRO) has been added to the S&P Global BMI Index. This announcement follows several other recent updates for the company, including executive promotions and price target adjustments from analysts. Alto Neuroscience is a clinical-stage biopharmaceutical compaโ€ฆ

Company news retained for context; no directional weight.
Scoring detailsDirect company coverage

Alto Neuroscience, Inc. (NYSE: ANRO) has been added to the S&P Global BMI Index. This announcement follows several other recent updates for the company, including executive promotions and price target adjustments from analysts. Alto Neuroscience is a clinical-stage biopharmaceutical company focused on developing personalized treatments for mental health conditions using its Precision Psychiatry Platform.

Published
21 Sep 2026 21:49
News subject
Market update
Why this score
No clear directional signal in the available text
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 17.3d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
EarningsFinancial MarketsLife Sciences

Alto Neuroscience presented its broad clinical-stage strategy in psychiatry at the H.C. Wainwright 28th Annual Global Investment Conference, highlighting its lead program ALTO-207 for treatment-resistant depression and two other Phase 2B programs, ALTO-300 and ALTO-100. The company emphasโ€ฆ

Company news retained for context; no directional weight.
Scoring detailsDirect company coverage

Alto Neuroscience presented its broad clinical-stage strategy in psychiatry at the H.C. Wainwright 28th Annual Global Investment Conference, highlighting its lead program ALTO-207 for treatment-resistant depression and two other Phase 2B programs, ALTO-300 and ALTO-100. The company emphasizes a precision psychiatry approach using biomarkers to identify responsive patients and improve trial efficiency. Management also discussed a strong financial position, upcoming data readouts in 2027, and efforts to enhance trial quality by addressing "professional patient" risks.

Published
14 Sep 2026 13:57
News subject
Market update
Why this score
Positive financial language
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 24.7d old
Text assessed
Available headline and article text
Duplicates
1 consolidated
Life Sciences
Company news retained for context; no directional weight.
Scoring detailsDirect company coverage
Published
09 Sep 2026 12:03
News subject
Market update
Why this score
No clear directional signal in the available text
Company focus
Main company ยท 100%
How it is used
Shown as company news ยท not used in the score
Story strength
Not directional
30-day weight
None ยท 29.7d old
Text assessed
Available headline and article text
Duplicates
1 consolidated

Earlier company news

ANRO news archive

66 older headlines

Stored newest first for historical research. It starts after the newest three pages above and then continues through older news. Each archive page is loaded only when it is opened.

Older news is kept in the archive

There are 66 older ANRO headlines. Open one page at a time when you need them.

Open older archive

Provider matches checked

Provider mentions not used in the score

9 not scored

A news provider linked these stories to ANRO, but the headline and available text are not mainly about Alto Neuroscience, Inc.. They are kept here for transparency and do not affect the score, confidence, history or wider market totals.

Provider mentions are kept separate

Open the list to see which provider matches were checked and left out of ANRO sentiment.

Open provider mentions

How the page works

How to read the score

The score shows direction

It describes the weighted balance of qualifying headlines. A score of 50 can mean balanced news or that there is not enough evidence; the status label explains which.

Confidence is separate

Confidence measures depth, source breadth, direct relevance, freshness and agreement. It does not rise merely because the tone is extreme. This is a rule-based evidence measure, not a calibrated probability.

Price is confirmation

Weekly price response, trend and fair-value position test whether the market is accepting or rejecting the news. They never rewrite the news score.

What the page does

It measures news already published. It is not a forecast, recommendation or price target.

Evidence context