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NASDAQEquity · Volume & Price

QURE

Uniqure NV

US Healthcare Biotechnology

52-week price-61.1%
Latest week
9 Oct 2026
Chart Console
Weekly close
22.59 USD
Daily Price
Fair value
17.53 USD
Weekly Trend
Next-week expectancy
Undecided 53.38%
Weekly Report

Sharemaestro · Completed weekly data

Volume & Price

Where trading activity is concentrated, how it has changed, and what volume adds to the price move.

Open Volume & Price screener →

Latest week ·

Price is within the earlier activity area

The latest close is inside the activity area established before the last four weeks. 2 of those four closes were inside that area. Recent volume balance is negative; the estimated activity centre is higher.

52 weeks2025-10-17 to 2026-10-09Weekly volume estimate

The relationship beneath price · 2026-10-09

Heavy volume, limited progress

These diagnostics use fixed windows through the latest completed week. Chart period controls below change the activity study separately.

Four-week price move-49.3%-47.0% over thirteen weeks
Latest relative volume1.56×1.36× recent four-week median
Closing pressure-61.6%Volume-weighted position within weekly ranges
Up-week volume share26.6%73.4% in declining weeks · last 13 weeks

Price and pressure through time

Compare four-week returns with four-week closing pressure. Opposite signs reveal disagreement; agreement alone is not predictive.

View weekly evidence values
Week4-week returnPressureRelative volume
2025-10-17318.2%55.2%1.75×
2025-10-2412.3%-21.3%1.23×
2025-10-3123.3%2.6%1.47×
2025-11-07-54.9%-27.4%8.60×
2025-11-14-48.5%-5.5%2.55×
2025-11-21-54.4%-8.9%1.72×
2025-11-28-59.4%-15.1%0.82×
2025-12-05-23.3%-23.9%2.51×
2025-12-12-34.7%-66.5%1.60×
2025-12-19-13.7%-24.6%3.40×
2025-12-26-9.8%-18.3%0.61×
2026-01-029.7%-0.7%0.49×
2026-01-0929.8%20.5%1.30×
2026-01-16-4.8%-12.8%1.04×
2026-01-231.1%2.7%0.87×
2026-01-30-2.9%-4.9%0.73×
2026-02-061.3%-1.5%1.36×
2026-02-13-10.3%-17.4%0.81×
2026-02-20-6.6%-26.9%0.73×
2026-02-27-31.2%-56.5%2.96×
2026-03-06-44.4%9.9%5.55×
2026-03-13-24.2%-2.8%2.51×
2026-03-20-31.3%-3.8%1.13×
2026-03-27-5.5%15.6%0.74×
2026-04-0320.3%-42.5%0.49×
2026-04-10-1.0%-6.9%0.73×
2026-04-179.3%3.5%0.77×
2026-04-2422.1%28.9%0.60×
2026-05-0111.5%17.5%1.03×
2026-05-0879.8%40.2%1.59×
2026-05-1553.9%17.2%1.17×
2026-05-2234.2%7.0%0.54×
2026-05-2949.1%13.3%0.65×
2026-06-05-4.4%-42.4%1.06×
2026-06-121.9%-32.6%0.57×
2026-06-1991.4%29.5%3.03×
2026-06-2666.5%20.3%1.96×
2026-07-0358.1%24.5%0.89×
2026-07-1054.6%23.4%0.82×
2026-07-17-13.1%-12.7%0.65×
2026-07-24-18.0%-30.6%0.61×
2026-07-314.4%24.7%1.47×
2026-08-078.9%30.6%0.74×
2026-08-1420.8%51.4%0.60×
2026-08-2124.1%58.1%0.55×
2026-08-2811.7%31.9%0.69×
2026-09-04-4.1%-8.3%0.90×
2026-09-11-8.5%-35.3%0.64×
2026-09-18-9.0%-29.1%0.86×
2026-09-25-21.5%-45.3%1.27×
2026-10-02-47.3%-70.9%6.56×
2026-10-09-49.3%-61.6%1.56×

Does support survive a longer view?

Advancing-week volume share against price return and closing pressure.

4 weeks0%up-week volume-49.3%price return-61.6%pressure
13 weeks27%up-week volume-47.0%price return-29.8%pressure
26 weeks51%up-week volume46.9%price return-7.9%pressure
52 weeks43%up-week volume-63.3%price return-10.8%pressure

A high advancing-volume share alongside weak closing pressure can mean price rose between closes but finished low within its weekly ranges. The two measures answer different questions.

Effort and result

100% price efficiency

Four-week net price movement as a share of the total close-to-close path. Lower readings indicate more back-and-forth movement, regardless of volume.

Latest close: 53% of the way from the weekly low to high.

Volume-weighted return tilt

-10.09 percentage points

The volume-weighted average weekly return minus the ordinary average over thirteen weeks. Positive means more volume coincided with stronger returns; negative means volume leaned toward weaker returns.

An association within this listing, not measured capital flow.

Constructive confirmation

6.6 / 100

Price direction0.0 / 30
Closing pressure0.0 / 30
Up-week volume6.6 / 25
Volume confirmation0.0 / 15

Fixed weights favour supported advances. A low score can still contain useful bearish or reversal research.

Test the volume contribution

Did heavier trading change what followed?

Compare high-volume and ordinary-volume weeks with the same price direction.

High volume is at least 1.5× its preceding 26-week median; ordinary volume is 0.75–1.25×. Returns start at that week’s close. Each group uses non-overlapping completed outcomes.

Starting observationAfterHigh-volume examplesMedian returnOrdinary examplesMedian returnDifference
Advancing weeks4 weeks19-4.4%35-5.9%1.5 points
Advancing weeks13 weeks12-11.1%17-7.3%-3.8 points
Declining weeks4 weeks23-5.5%36-4.1%-1.4 points
Declining weeks13 weeks133.8%172.3%1.5 points

At least eight completed examples in both groups are required. Groups may overlap each other, and differ in volatility, trend and market conditions; their difference is not a causal volume effect or a statistical claim of edge. Up to six years of available history; price returns exclude dividends, costs and execution. Fixed definitions have not been validated out of sample.

Inspect the dated observations

Advancing weeks · 4 weeks

Volume groupObservationOutcome dateReturn
High volume2021-09-032021-10-013.0%
High volume2021-12-242022-01-21-19.0%
High volume2022-06-242022-07-2228.7%
High volume2022-11-252022-12-23-13.4%
High volume2023-06-302023-07-28-14.0%
High volume2023-10-062023-11-03-12.1%
High volume2023-11-032023-12-0116.8%
High volume2023-12-012023-12-29-5.2%
High volume2024-07-122024-08-09-18.0%
High volume2024-10-042024-11-013.7%
High volume2024-11-082024-12-06-4.4%
High volume2024-12-062025-01-03140.8%
High volume2025-04-182025-05-165.4%
High volume2025-09-262025-10-2412.3%
High volume2025-11-142025-12-12-34.7%
High volume2025-12-192026-01-16-4.8%
High volume2026-03-132026-04-10-1.0%
High volume2026-05-082026-06-05-4.4%
High volume2026-06-192026-07-17-13.1%
Ordinary volume2021-05-072021-06-048.5%
Ordinary volume2021-06-042021-07-02-13.7%
Ordinary volume2021-08-272021-09-2415.0%
Ordinary volume2021-10-292021-11-26-5.4%
Ordinary volume2021-12-102022-01-07-31.0%
Ordinary volume2022-01-142022-02-11-16.7%
Ordinary volume2022-02-252022-03-25-0.7%
Ordinary volume2022-04-012022-04-29-23.2%
Ordinary volume2022-05-272022-06-2428.3%
Ordinary volume2022-07-082022-08-0512.2%
Ordinary volume2022-08-052022-09-02-19.1%
Ordinary volume2022-09-022022-09-30-9.2%
Ordinary volume2022-09-302022-10-281.5%
Ordinary volume2022-11-042022-12-0235.3%
Ordinary volume2022-12-232023-01-20-6.0%
Ordinary volume2023-02-032023-03-03-5.9%
Ordinary volume2023-03-032023-03-31-5.0%
Ordinary volume2023-03-312023-04-28-3.6%
Ordinary volume2023-05-052023-06-02-6.0%
Ordinary volume2023-06-022023-06-30-42.8%
Ordinary volume2023-08-182023-09-15-8.7%
Ordinary volume2023-12-082024-01-05-8.4%
Ordinary volume2024-01-262024-02-238.4%
Ordinary volume2024-06-072024-07-05-28.0%
Ordinary volume2024-10-252024-11-22-11.6%
Ordinary volume2025-01-242025-02-21-18.1%
Ordinary volume2025-03-142025-04-11-37.1%
Ordinary volume2025-05-022025-05-30-2.0%
Ordinary volume2025-07-252025-08-223.9%
Ordinary volume2025-09-052025-10-03206.0%
Ordinary volume2025-10-242025-11-21-54.4%
Ordinary volume2026-01-232026-02-20-6.6%
Ordinary volume2026-03-202026-04-179.3%
Ordinary volume2026-04-172026-05-1553.9%
Ordinary volume2026-07-102026-08-078.9%

Advancing weeks · 13 weeks

Volume groupObservationOutcome dateReturn
High volume2021-09-032021-12-03-12.8%
High volume2021-12-242022-03-25-24.7%
High volume2022-06-242022-09-23-9.5%
High volume2022-11-252023-02-24-25.8%
High volume2023-06-302023-09-29-41.5%
High volume2023-10-062024-01-05-5.8%
High volume2024-07-122024-10-11-35.2%
High volume2024-11-082025-02-0787.8%
High volume2025-04-182025-07-1815.3%
High volume2025-09-262025-12-26-54.3%
High volume2026-03-132026-06-1277.5%
High volume2026-06-192026-09-18-5.0%
Ordinary volume2021-05-072021-08-06-6.2%
Ordinary volume2021-08-272021-11-26-1.9%
Ordinary volume2021-12-102022-03-11-46.9%
Ordinary volume2022-04-012022-07-01-1.4%
Ordinary volume2022-07-082022-10-07-15.3%
Ordinary volume2022-10-072023-01-0619.1%
Ordinary volume2023-01-062023-04-07-14.9%
Ordinary volume2023-05-052023-08-04-55.8%
Ordinary volume2023-08-182023-11-17-20.5%
Ordinary volume2023-12-082024-03-08-27.2%
Ordinary volume2024-06-072024-09-061.7%
Ordinary volume2024-10-252025-01-24139.8%
Ordinary volume2025-01-242025-04-25-9.5%
Ordinary volume2025-05-022025-08-01-7.3%
Ordinary volume2025-08-152025-11-1484.7%
Ordinary volume2026-01-232026-04-24-28.1%
Ordinary volume2026-05-012026-07-31128.1%

Declining weeks · 4 weeks

Volume groupObservationOutcome dateReturn
High volume2021-06-252021-07-23-15.9%
High volume2021-09-242021-10-22-15.7%
High volume2021-12-172022-01-14-4.8%
High volume2022-02-182022-03-1812.2%
High volume2022-06-172022-07-1567.8%
High volume2022-08-122022-09-090.6%
High volume2022-09-162022-10-14-3.0%
High volume2022-12-022022-12-30-12.9%
High volume2023-06-162023-07-14-44.0%
High volume2023-07-142023-08-11-21.6%
High volume2023-09-082023-10-06-12.2%
High volume2023-10-272023-11-2422.2%
High volume2023-12-222024-01-19-12.2%
High volume2024-03-012024-03-29-7.0%
High volume2024-07-192024-08-16-14.6%
High volume2025-01-102025-02-075.6%
High volume2025-04-042025-05-0264.8%
High volume2025-05-092025-06-0635.0%
High volume2025-08-012025-08-2919.2%
High volume2025-09-192025-10-17318.2%
High volume2025-10-172025-11-14-48.5%
High volume2025-11-212025-12-19-13.7%
High volume2026-02-272026-03-27-5.5%
Ordinary volume2021-04-232021-05-215.2%
Ordinary volume2021-08-202021-09-1737.4%
Ordinary volume2021-10-012021-10-29-4.9%
Ordinary volume2021-12-032021-12-31-23.6%
Ordinary volume2022-01-212022-02-18-11.2%
Ordinary volume2022-04-082022-05-06-20.3%
Ordinary volume2022-05-132022-06-10-0.5%
Ordinary volume2022-06-102022-07-0859.9%
Ordinary volume2022-08-192022-09-161.8%
Ordinary volume2022-09-232022-10-2111.3%
Ordinary volume2022-10-282022-11-2541.3%
Ordinary volume2022-12-092023-01-063.0%
Ordinary volume2023-01-202023-02-17-5.4%
Ordinary volume2023-02-172023-03-17-6.6%
Ordinary volume2023-04-072023-05-059.1%
Ordinary volume2023-06-092023-07-07-42.1%
Ordinary volume2023-07-072023-08-04-17.0%
Ordinary volume2023-08-252023-09-22-17.3%
Ordinary volume2023-09-292023-10-27-16.1%
Ordinary volume2024-01-122024-02-09-4.1%
Ordinary volume2024-02-162024-03-15-11.6%
Ordinary volume2024-07-052024-08-0290.4%
Ordinary volume2024-08-092024-09-06-24.2%
Ordinary volume2024-09-202024-10-1819.8%
Ordinary volume2024-11-012024-11-291.9%
Ordinary volume2025-02-072025-03-07-16.4%
Ordinary volume2025-03-282025-04-2513.7%
Ordinary volume2025-05-302025-06-27-4.2%
Ordinary volume2025-06-272025-07-259.0%
Ordinary volume2025-09-122025-10-10273.4%
Ordinary volume2025-11-282025-12-26-9.8%
Ordinary volume2026-01-162026-02-13-10.3%
Ordinary volume2026-02-132026-03-13-24.2%
Ordinary volume2026-05-152026-06-121.9%
Ordinary volume2026-07-032026-07-314.4%
Ordinary volume2026-09-042026-10-02-47.3%

Declining weeks · 13 weeks

Volume groupObservationOutcome dateReturn
High volume2021-06-252021-09-249.2%
High volume2021-09-242021-12-24-34.1%
High volume2021-12-312022-04-01-6.2%
High volume2022-06-172022-09-1637.4%
High volume2022-09-162022-12-1619.2%
High volume2023-06-162023-09-15-59.3%
High volume2023-09-152023-12-154.4%
High volume2023-12-222024-03-22-16.5%
High volume2024-07-192024-10-18-17.1%
High volume2025-01-102025-04-11-35.5%
High volume2025-05-092025-08-083.8%
High volume2025-09-192025-12-1973.0%
High volume2026-02-272026-05-2982.5%
Ordinary volume2021-04-232021-07-23-19.4%
Ordinary volume2021-08-202021-11-1910.6%
Ordinary volume2021-12-032022-03-04-41.9%
Ordinary volume2022-04-082022-07-0824.0%
Ordinary volume2022-08-192022-11-1816.4%
Ordinary volume2022-12-092023-03-10-14.0%
Ordinary volume2023-03-102023-06-092.3%
Ordinary volume2023-06-092023-09-08-59.6%
Ordinary volume2023-09-292023-12-290.9%
Ordinary volume2024-01-122024-04-12-22.7%
Ordinary volume2024-07-052024-10-0447.1%
Ordinary volume2024-11-012025-01-31168.6%
Ordinary volume2025-02-072025-05-09-12.6%
Ordinary volume2025-05-302025-08-2912.9%
Ordinary volume2025-09-122025-12-1218.4%
Ordinary volume2026-01-162026-04-17-23.0%
Ordinary volume2026-05-152026-08-1479.7%

Price, activity and volume balance

Where volume is concentrated

2026-10-09Close 22.59
Weekly priceEstimated volume at priceMost active priceEarlier activity areaEstimated volume balance

Move over the chart, tap a week, or use the arrow keys to inspect it. The profile estimates where volume sits within weekly price ranges. The lower chart accumulates volume weighted by where each week closed in its range; its starting point changes with the selected period. This is not trade-based CVD.

Most active price23.55
Earlier activity area11.35 – 32.27
Recent volume balance-61.6%
Recent weekly volume1.19×
View chart values
Completed weekly observations
Week endingCloseVolume
2025-10-1758.0010785502
2025-10-2461.017545627
2025-10-3167.699060961
2025-11-0727.7957801413
2025-11-1429.8817133011
2025-11-2127.8111564306
2025-11-2827.515892559
2025-12-0521.3317973945
2025-12-1219.5111536182
2025-12-1923.9925871813
2025-12-2624.815058306
2026-01-0223.394103900
2026-01-0925.3210783297
2026-01-1622.849918266
2026-01-2325.088629201
2026-01-3022.727294829
2026-02-0625.6512893586
2026-02-1320.508079094
2026-02-2023.437269541
2026-02-2715.6329372371
2026-03-0614.2757490065
2026-03-1315.5327112034
2026-03-2016.0912666571
2026-03-2714.778558449
2026-04-0317.165451178
2026-04-1015.387919073
2026-04-1717.587997095
2026-04-2418.035675365
2026-05-0119.139772522
2026-05-0827.6615672219
2026-05-1527.0511563446
2026-05-2224.195360999
2026-05-2928.535938679
2026-06-0526.459772597
2026-06-1227.575210089
2026-06-1946.2926040695
2026-06-2647.5116885754
2026-07-0341.818234705
2026-07-1042.637528178
2026-07-1740.255565133
2026-07-2438.975157209
2026-07-3143.6312003273
2026-08-0746.426239375
2026-08-1448.624906748
2026-08-2148.374496603
2026-08-2848.725634599
2026-09-0444.507191194
2026-09-1144.514917296
2026-09-1844.006293347
2026-09-2538.238534106
2026-10-0223.4644249558
2026-10-0922.5911511802

Earlier and recent activity

What has changed?

The recent comparison uses the last four completed weeks.

Activity centre

Higher

The recent centre moved +14.11% against the earlier part of this period.

Price and volume

No clear disagreement

Price changed -49.25% over four weeks. Volume balance is -61.6% on a scale from −100% to +100%.

Volume and price movement

Recent volume is close to its earlier norm

Recent median weekly volume is 1.19× the earlier median. This describes price response, not the identity of buyers or sellers.

Recent closes

2 of 4 closes inside

Price was above the earlier area before these four weeks. The earlier boundaries stay fixed for this comparison.

Activity over time

Darker cells show more estimated volume at that price. Use the chart to see where activity has moved. For longer periods, a column combines several weeks.

Volume and price movement

Each dot is a week. Compare weekly volume with the move from open to close.

What to check next

Holding outside the area

Watch which boundary price moves beyond and whether later closes remain outside it.

Returning inside

Price is currently inside the earlier area. Repeated closes here would show that activity remains in the same price range.

Price and volume disagreeing

There is no clear disagreement at present. Check whether volume balance continues to support any further price move.

Same stock · Earlier observations

Previous examples

Descriptive history, not a forecast.

Comparisons use the same period length, position relative to the earlier activity area and direction of recent volume balance. Outcomes do not overlap for each following period. At least five examples are needed to show a matched median. The median is the middle result; the all-period median includes earlier periods regardless of their volume reading.

Subsequent price changes
AfterExamplesMedian changeSample
4 weeks243.58Available
13 weeks1414.07Available

Returns are close-to-close price changes. Interim lows show the lowest price reached during the period. Dividends, fees and trade execution are not included. The available history contains up to six years of weekly observations.

Connected research

Test the same listing from another angle

How to read this report

Choose the period

The selected period sets the profile and volume balance starting point. “Start from a date” uses the first available week on or after that date. At least 13 consecutive weeks are required.

Compare earlier activity

The earlier activity area contains most of the estimated volume before the last four weeks. The activity centre is the average estimated price, weighted by volume. Compare subsequent closes with its boundaries, then read the volume balance alongside the price move.

Check the data

Volume is reported for the whole week. The distribution within the range and the direction of pressure are estimates. They cannot identify individual trades, investor holdings or institutional buying.

Reports use saved weekly data and refresh when those records change. Missing or invalid weeks restrict the available periods.

QURE · Volume & Price

Evidence context