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NASDAQEquity · Volume & Price

TWST

Twist Bioscience Corp

US Healthcare Diagnostics & Research

52-week price+467.4%
Latest week
9 Oct 2026
Chart Console
Weekly close
159.78 USD
Daily Price
Fair value
49.09 USD
Weekly Trend
Next-week expectancy
Undecided 51.91%
Weekly Report

Sharemaestro · Completed weekly data

Volume & Price

Where trading activity is concentrated, how it has changed, and what volume adds to the price move.

Open Volume & Price screener →

Latest week ·

Price is above the earlier activity area

The latest close is above the activity area established before the last four weeks. 4 of those four closes were above that area. Recent volume balance is positive; the estimated activity centre is higher.

52 weeks2025-10-17 to 2026-10-09Weekly volume estimate

The relationship beneath price · 2026-10-09

Volume-supported advance

These diagnostics use fixed windows through the latest completed week. Chart period controls below change the activity study separately.

Four-week price move25.6%76.3% over thirteen weeks
Latest relative volume3.30×1.85× recent four-week median
Closing pressure12.0%Volume-weighted position within weekly ranges
Up-week volume share65.7%34.3% in declining weeks · last 13 weeks
Rejected range breakoutAt least twice normal volume

Price and pressure through time

Compare four-week returns with four-week closing pressure. Opposite signs reveal disagreement; agreement alone is not predictive.

View weekly evidence values
Week4-week returnPressureRelative volume
2025-10-171.0%-36.3%1.57×
2025-10-2426.8%-0.7%1.77×
2025-10-315.9%-10.5%0.97×
2025-11-07-3.0%-4.4%1.19×
2025-11-14-4.6%14.6%1.98×
2025-11-21-16.3%8.7%2.11×
2025-11-28-2.7%22.4%0.75×
2025-12-056.7%39.7%1.00×
2025-12-1215.1%37.8%0.98×
2025-12-1913.8%21.7%1.14×
2025-12-263.3%-5.6%0.50×
2026-01-020.3%-18.6%0.58×
2026-01-0914.2%8.6%1.14×
2026-01-1627.4%20.0%1.05×
2026-01-2329.9%30.1%0.74×
2026-01-3026.8%18.0%0.81×
2026-02-0639.4%47.0%1.61×
2026-02-1318.6%39.2%0.95×
2026-02-2013.2%14.4%1.19×
2026-02-2714.2%10.1%0.64×
2026-03-06-4.7%-22.8%0.66×
2026-03-13-11.9%-50.7%0.66×
2026-03-20-13.4%-48.5%0.69×
2026-03-27-5.1%-49.9%1.09×
2026-04-037.0%-38.6%0.69×
2026-04-1010.7%-38.2%0.67×
2026-04-1742.2%7.2%1.31×
2026-04-2436.9%21.7%1.20×
2026-05-0120.3%15.6%1.17×
2026-05-0818.7%10.6%1.28×
2026-05-15-17.8%-26.3%1.04×
2026-05-22-0.6%-2.5%1.20×
2026-05-2910.7%-5.8%1.12×
2026-06-0521.8%-1.6%1.24×
2026-06-1254.9%32.9%1.40×
2026-06-1944.6%38.1%1.53×
2026-06-2649.3%48.7%1.92×
2026-07-0343.4%52.2%0.92×
2026-07-1019.0%24.7%1.16×
2026-07-177.2%16.7%0.87×
2026-07-24-9.6%-13.1%0.72×
2026-07-31-7.8%6.9%1.02×
2026-08-0727.6%55.8%1.50×
2026-08-1426.3%32.6%1.01×
2026-08-2161.3%58.2%1.37×
2026-08-2854.4%37.5%1.05×
2026-09-047.8%-6.5%0.96×
2026-09-117.3%2.2%0.82×
2026-09-1814.7%8.5%1.62×
2026-09-2529.3%44.9%1.75×
2026-10-0251.3%54.0%1.89×
2026-10-0925.6%12.0%3.30×

Does support survive a longer view?

Advancing-week volume share against price return and closing pressure.

4 weeks61%up-week volume25.6%price return12.0%pressure
13 weeks66%up-week volume76.3%price return17.8%pressure
26 weeks66%up-week volume233.5%price return17.5%pressure
52 weeks61%up-week volume412.3%price return11.7%pressure

A high advancing-volume share alongside weak closing pressure can mean price rose between closes but finished low within its weekly ranges. The two measures answer different questions.

Effort and result

36% price efficiency

Four-week net price movement as a share of the total close-to-close path. Lower readings indicate more back-and-forth movement, regardless of volume.

Latest close: 20% of the way from the weekly low to high.

Volume-weighted return tilt

-0.74 percentage points

The volume-weighted average weekly return minus the ordinary average over thirteen weeks. Positive means more volume coincided with stronger returns; negative means volume leaned toward weaker returns.

An association within this listing, not measured capital flow.

Constructive confirmation

65.0 / 100

Price direction30.0 / 30
Closing pressure3.6 / 30
Up-week volume16.4 / 25
Volume confirmation15.0 / 15

Fixed weights favour supported advances. A low score can still contain useful bearish or reversal research.

Test the volume contribution

Did heavier trading change what followed?

Compare high-volume and ordinary-volume weeks with the same price direction.

High volume is at least 1.5× its preceding 26-week median; ordinary volume is 0.75–1.25×. Returns start at that week’s close. Each group uses non-overlapping completed outcomes.

Starting observationAfterHigh-volume examplesMedian returnOrdinary examplesMedian returnDifference
Advancing weeks4 weeks21-3.0%380.3%-3.3 points
Advancing weeks13 weeks121.1%15-5.2%6.3 points
Declining weeks4 weeks140.6%371.1%-0.5 points
Declining weeks13 weeks8-6.3%18-4.5%-1.8 points

At least eight completed examples in both groups are required. Groups may overlap each other, and differ in volatility, trend and market conditions; their difference is not a causal volume effect or a statistical claim of edge. Up to six years of available history; price returns exclude dividends, costs and execution. Fixed definitions have not been validated out of sample.

Inspect the dated observations

Advancing weeks · 4 weeks

Volume groupObservationOutcome dateReturn
High volume2021-12-102022-01-07-19.7%
High volume2022-02-042022-03-04-19.1%
High volume2022-03-182022-04-15-15.8%
High volume2022-05-062022-06-03-3.0%
High volume2022-06-172022-07-1536.4%
High volume2022-12-162023-01-132.8%
High volume2023-03-172023-04-14-15.4%
High volume2023-05-052023-06-0226.5%
High volume2023-11-172023-12-1544.2%
High volume2023-12-152024-01-124.4%
High volume2024-05-032024-05-311.7%
High volume2024-06-072024-07-05-3.9%
High volume2024-12-202025-01-17-0.8%
High volume2025-03-072025-04-04-8.2%
High volume2025-04-112025-05-09-20.7%
High volume2025-08-152025-09-12-10.0%
High volume2025-09-192025-10-171.0%
High volume2025-10-242025-11-21-16.3%
High volume2025-11-212025-12-1913.8%
High volume2026-02-062026-03-06-4.7%
High volume2026-06-192026-07-177.2%
Ordinary volume2021-05-212021-06-1816.6%
Ordinary volume2021-08-272021-09-240.5%
Ordinary volume2021-10-152021-11-123.3%
Ordinary volume2022-07-082022-08-0524.8%
Ordinary volume2022-08-052022-09-02-26.5%
Ordinary volume2022-09-302022-10-28-5.3%
Ordinary volume2022-10-282022-11-25-23.8%
Ordinary volume2022-12-022022-12-30-16.5%
Ordinary volume2023-01-132023-02-10-8.7%
Ordinary volume2023-03-032023-03-31-22.4%
Ordinary volume2023-04-142023-05-12-14.5%
Ordinary volume2023-05-192023-06-1640.5%
Ordinary volume2023-06-162023-07-1427.3%
Ordinary volume2023-07-142023-08-11-4.3%
Ordinary volume2023-11-032023-12-0132.8%
Ordinary volume2023-12-012023-12-2948.8%
Ordinary volume2023-12-292024-01-26-12.4%
Ordinary volume2024-02-092024-03-08-1.6%
Ordinary volume2024-04-262024-05-2433.9%
Ordinary volume2024-06-212024-07-195.8%
Ordinary volume2024-07-262024-08-23-24.8%
Ordinary volume2024-09-132024-10-11-5.3%
Ordinary volume2024-11-082024-12-0616.1%
Ordinary volume2024-12-062025-01-03-10.2%
Ordinary volume2025-01-172025-02-140.1%
Ordinary volume2025-04-252025-05-23-29.5%
Ordinary volume2025-05-302025-06-2722.6%
Ordinary volume2025-06-272025-07-250.2%
Ordinary volume2025-07-252025-08-22-20.6%
Ordinary volume2025-08-222025-09-19-2.5%
Ordinary volume2025-11-282025-12-263.3%
Ordinary volume2026-01-092026-02-0639.4%
Ordinary volume2026-03-272026-04-2436.9%
Ordinary volume2026-04-242026-05-22-0.6%
Ordinary volume2026-05-222026-06-1944.6%
Ordinary volume2026-07-172026-08-1426.3%
Ordinary volume2026-08-142026-09-117.3%
Ordinary volume2026-09-112026-10-0925.6%

Advancing weeks · 13 weeks

Volume groupObservationOutcome dateReturn
High volume2021-12-102022-03-11-47.3%
High volume2022-03-182022-06-17-38.4%
High volume2022-06-172022-09-1620.6%
High volume2022-12-162023-03-17-34.6%
High volume2023-03-172023-06-1610.9%
High volume2023-11-172024-02-1670.3%
High volume2024-05-032024-08-024.3%
High volume2024-12-202025-03-21-10.5%
High volume2025-04-112025-07-11-2.1%
High volume2025-08-152025-11-14-4.5%
High volume2025-11-212026-02-2070.1%
High volume2026-06-192026-09-1890.7%
Ordinary volume2021-05-212021-08-205.3%
Ordinary volume2021-08-272021-11-26-14.9%
Ordinary volume2022-07-082022-10-07-22.7%
Ordinary volume2022-10-282023-01-27-12.7%
Ordinary volume2023-01-272023-04-28-57.2%
Ordinary volume2023-05-192023-08-1849.4%
Ordinary volume2023-11-032024-02-0296.1%
Ordinary volume2024-02-092024-05-1011.0%
Ordinary volume2024-05-172024-08-16-7.3%
Ordinary volume2024-09-132024-12-131.2%
Ordinary volume2025-01-172025-04-18-22.6%
Ordinary volume2025-04-252025-07-25-10.3%
Ordinary volume2025-07-252025-10-24-5.2%
Ordinary volume2025-11-282026-02-2746.6%
Ordinary volume2026-03-272026-06-26124.2%

Declining weeks · 4 weeks

Volume groupObservationOutcome dateReturn
High volume2021-11-262021-12-24-11.0%
High volume2022-01-072022-02-04-10.9%
High volume2022-02-112022-03-11-21.8%
High volume2022-11-182022-12-161.8%
High volume2023-02-032023-03-03-23.2%
High volume2024-08-022024-08-300.6%
High volume2024-11-152024-12-1328.8%
High volume2025-02-072025-03-07-24.6%
High volume2025-04-042025-05-028.4%
High volume2025-05-092025-06-062.4%
High volume2025-08-082025-09-050.5%
High volume2025-09-122025-10-1023.2%
High volume2025-10-172025-11-14-4.6%
High volume2025-11-142025-12-1215.1%
Ordinary volume2021-05-142021-06-1123.7%
Ordinary volume2021-08-062021-09-033.6%
Ordinary volume2021-10-012021-10-2912.6%
Ordinary volume2021-11-122021-12-10-28.7%
Ordinary volume2021-12-242022-01-21-37.4%
Ordinary volume2022-03-042022-04-019.9%
Ordinary volume2022-04-082022-05-06-31.7%
Ordinary volume2022-07-012022-07-2918.0%
Ordinary volume2022-10-072022-11-04-0.5%
Ordinary volume2022-11-042022-12-02-12.3%
Ordinary volume2022-12-092023-01-064.0%
Ordinary volume2023-02-242023-03-24-15.6%
Ordinary volume2023-03-242023-04-21-15.0%
Ordinary volume2023-04-212023-05-19-5.2%
Ordinary volume2023-06-232023-07-2145.3%
Ordinary volume2023-08-112023-09-080.5%
Ordinary volume2023-09-152023-10-13-19.0%
Ordinary volume2023-11-102023-12-0859.9%
Ordinary volume2024-01-052024-02-027.7%
Ordinary volume2024-03-082024-04-05-13.2%
Ordinary volume2024-04-052024-05-0326.4%
Ordinary volume2024-05-242024-06-2120.7%
Ordinary volume2024-08-162024-09-137.8%
Ordinary volume2024-09-202024-10-181.1%
Ordinary volume2024-12-132025-01-10-8.2%
Ordinary volume2025-01-102025-02-0720.0%
Ordinary volume2025-03-282025-04-25-0.6%
Ordinary volume2025-05-022025-05-30-25.3%
Ordinary volume2025-07-112025-08-08-32.6%
Ordinary volume2025-08-292025-09-26-0.2%
Ordinary volume2025-09-262025-10-2426.8%
Ordinary volume2025-10-312025-11-28-2.7%
Ordinary volume2025-12-122026-01-0914.2%
Ordinary volume2026-01-302026-02-2714.2%
Ordinary volume2026-05-012026-05-2910.7%
Ordinary volume2026-07-032026-07-31-7.8%
Ordinary volume2026-08-282026-09-2529.3%

Declining weeks · 13 weeks

Volume groupObservationOutcome dateReturn
High volume2021-11-262022-02-25-42.1%
High volume2022-11-182023-02-17-9.2%
High volume2023-02-172023-05-19-42.1%
High volume2024-08-022024-11-01-3.3%
High volume2024-11-152025-02-1429.0%
High volume2025-02-142025-05-16-35.0%
High volume2025-08-082025-11-0718.1%
High volume2025-11-142026-02-1382.8%
Ordinary volume2021-05-142021-08-138.5%
Ordinary volume2021-08-202021-11-1910.1%
Ordinary volume2021-11-192022-02-18-51.9%
Ordinary volume2022-03-042022-06-03-36.7%
Ordinary volume2022-07-012022-09-30-5.0%
Ordinary volume2022-10-072023-01-06-22.2%
Ordinary volume2023-02-242023-05-26-24.9%
Ordinary volume2023-06-232023-09-2217.7%
Ordinary volume2023-09-292023-12-2981.9%
Ordinary volume2024-01-052024-04-05-4.0%
Ordinary volume2024-04-052024-07-0548.6%
Ordinary volume2024-08-162024-11-15-15.3%
Ordinary volume2024-12-132025-03-14-15.9%
Ordinary volume2025-03-282025-06-27-11.0%
Ordinary volume2025-07-112025-10-10-18.0%
Ordinary volume2025-10-312026-01-3024.9%
Ordinary volume2026-01-302026-05-0147.1%
Ordinary volume2026-05-012026-07-3151.6%

Price, activity and volume balance

Where volume is concentrated

2026-10-09Close 159.78
Weekly priceEstimated volume at priceMost active priceEarlier activity areaEstimated volume balance

Move over the chart, tap a week, or use the arrow keys to inspect it. The profile estimates where volume sits within weekly price ranges. The lower chart accumulates volume weighted by where each week closed in its range; its starting point changes with the selected period. This is not trade-based CVD.

Most active price31.48
Earlier activity area23.30 – 83.86
Recent volume balance12.0%
Recent weekly volume1.90×
View chart values
Completed weekly observations
Week endingCloseVolume
2025-10-1728.168786872
2025-10-2434.1110159371
2025-10-3132.895772967
2025-11-0730.277050727
2025-11-1426.8711748548
2025-11-2128.5612500350
2025-11-2832.014734951
2025-12-0532.306295284
2025-12-1230.936025423
2025-12-1932.517059659
2025-12-2633.053201301
2026-01-0232.393758924
2026-01-0935.327308155
2026-01-1641.417160091
2026-01-2342.945198768
2026-01-3041.075692346
2026-02-0649.2411351370
2026-02-1349.116697190
2026-02-2048.598174119
2026-02-2746.924495765
2026-03-0646.944666662
2026-03-1343.284667936
2026-03-2042.074719391
2026-03-2744.537237827
2026-04-0350.214768798
2026-04-1047.914378638
2026-04-1759.818045295
2026-04-2460.947400736
2026-05-0160.407196847
2026-05-0856.858301717
2026-05-1549.176768309
2026-05-2260.577770118
2026-05-2966.877303669
2026-06-0569.228331102
2026-06-1276.179693101
2026-06-1987.5610887580
2026-06-2699.8413786633
2026-07-0399.246674146
2026-07-1090.648390165
2026-07-1793.856253786
2026-07-2490.275191937
2026-07-3191.557368074
2026-08-07115.6710875153
2026-08-14118.577357029
2026-08-21145.5910019794
2026-08-28141.387731188
2026-09-04124.727036206
2026-09-11127.226034900
2026-09-18166.9911948580
2026-09-25182.8312929711
2026-10-02188.6714336039
2026-10-09159.7825582671

Earlier and recent activity

What has changed?

The recent comparison uses the last four completed weeks.

Activity centre

Higher

The recent centre moved +174.28% against the earlier part of this period.

Price and volume

No clear disagreement

Price changed +25.59% over four weeks. Volume balance is +12.0% on a scale from −100% to +100%.

Volume and price movement

More volume, clear price movement

Recent median weekly volume is 1.90× the earlier median. This describes price response, not the identity of buyers or sellers.

Recent closes

4 of 4 closes above

Price was above the earlier area before these four weeks. The earlier boundaries stay fixed for this comparison.

Activity over time

Darker cells show more estimated volume at that price. Use the chart to see where activity has moved. For longer periods, a column combines several weeks.

Volume and price movement

Each dot is a week. Compare weekly volume with the move from open to close.

What to check next

Holding outside the area

Further closes above the earlier area would show that price is staying outside it. Compare them with the direction of recent volume balance.

Returning inside

A close back inside the earlier area would weaken the move outside it. Check whether the return lasts more than one week.

Price and volume disagreeing

There is no clear disagreement at present. Check whether volume balance continues to support any further price move.

Same stock · Earlier observations

Previous examples

Descriptive history, not a forecast.

Comparisons use the same period length, position relative to the earlier activity area and direction of recent volume balance. Outcomes do not overlap for each following period. At least five examples are needed to show a matched median. The median is the middle result; the all-period median includes earlier periods regardless of their volume reading.

Subsequent price changes
AfterExamplesMedian changeSample
4 weeks125.05Available
13 weeks629.7Available

Returns are close-to-close price changes. Interim lows show the lowest price reached during the period. Dividends, fees and trade execution are not included. The available history contains up to six years of weekly observations.

Connected research

Test the same listing from another angle

How to read this report

Choose the period

The selected period sets the profile and volume balance starting point. “Start from a date” uses the first available week on or after that date. At least 13 consecutive weeks are required.

Compare earlier activity

The earlier activity area contains most of the estimated volume before the last four weeks. The activity centre is the average estimated price, weighted by volume. Compare subsequent closes with its boundaries, then read the volume balance alongside the price move.

Check the data

Volume is reported for the whole week. The distribution within the range and the direction of pressure are estimates. They cannot identify individual trades, investor holdings or institutional buying.

Reports use saved weekly data and refresh when those records change. Missing or invalid weeks restrict the available periods.

TWST · Volume & Price

Evidence context